1H-Indazole-5-carboxylicacid,3-forMyl-
- CAS No.
- 885519-98-2
- Chemical Name:
- 1H-Indazole-5-carboxylicacid,3-forMyl-
- Synonyms
- 3-ForMyl-1H-indazole-5-carboxylic;3-Formyl-5-indazole carbocylic acid;3-formyl-2H-indazole-5-carboxylic acid;1H-Indazole-5-carboxylicacid,3-forMyl-
- CBNumber:
- CB52594656
- Molecular Formula:
- C9H6N2O3
- Molecular Weight:
- 190.16
- MDL Number:
- MFCD06656900
- MOL File:
- 885519-98-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Formyl-1H-indazole-5-carboxylicAcid | F449605 | 50mg | $150 |
| 3-FORMYL-1H-INDAZOLE-5-CARBOXYLIC ACID 95.00% | CHM0078799 | 250MG | $633.06 |
| 3-Formyl-1H-indazole-5-carboxylicacid | 4338AC | 1g | $809 |
| 3-FORMYL-1H-INDAZOLE-5-CARBOXYLIC ACID 95.00% | CHM0078799 | 1G | $916.84 |
| 3-formyl-1H-indazole-5-carboxylicacid 97% | CM132881 | 1g | $316 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H319-H315 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| HS Code | 2933998090 |
1H-Indazole-5-carboxylicacid,3-forMyl- price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | F449605 | 3-Formyl-1H-indazole-5-carboxylicAcid | 885519-98-2 | 50mg | $150 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0078799 | 3-FORMYL-1H-INDAZOLE-5-CARBOXYLIC ACID 95.00% | 885519-98-2 | 250MG | $633.06 | 2021-12-16 | Buy |
| AK Scientific | 4338AC | 3-Formyl-1H-indazole-5-carboxylicacid | 885519-98-2 | 1g | $809 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0078799 | 3-FORMYL-1H-INDAZOLE-5-CARBOXYLIC ACID 95.00% | 885519-98-2 | 1G | $916.84 | 2021-12-16 | Buy |
| Chemenu | CM132881 | 3-formyl-1H-indazole-5-carboxylicacid 97% | 885519-98-2 | 1g | $316 | 2021-12-16 | Buy |
1H-Indazole-5-carboxylicacid,3-forMyl- Chemical Properties,Uses,Production
Uses
3-Formyl-1H-indazole-5-carboxylic Acid was prepared by nitrosation of indoles. Indazole derivatives are useful as kinase inhibitors.
Synthesis
1670-81-1
885519-98-2
The general procedure for the synthesis of 3-formyl-5-carboxyindazole from indole-5-carboxylic acid was as follows: i) Preparation of 3-formyl-1H-indazole-5-carboxylic acid: indole-5-carboxylic acid (5.5 g, 0.0338 mol) was dissolved in water (250 ml), followed by the addition of sodium nitrite (NaNO2, 23.5 g, 0.338 mol) and a hydrochloric acid solution (6 N 42 ml, 0.293 mol). The reaction mixture was stirred at room temperature for 12 hours. Upon completion of the reaction, the precipitate was collected by filtration, washed with water (270 ml) and dried at 50 °C to afford 3-formyl-1H-indazole-5-carboxylic acid (5.36 g, 0.028 mol, 83% yield), which could be used in the subsequent steps without further purification.
References
[1] Patent: US2006/142247, 2006, A1. Location in patent: Page/Page column 39
[2] RSC Advances, 2018, vol. 8, # 24, p. 13121 - 13128
[3] Patent: WO2007/107346, 2007, A1. Location in patent: Page/Page column 35
1H-Indazole-5-carboxylicacid,3-forMyl- Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 3993 | 55 |
| Shanghai Devinchem Ltd | 027-65318838 13646286950 | sales@devinchem.com | China | 2975 | 58 |
| Bide Pharmatech Ltd. | 400-400-164-7117 18317119277 | product02@bidepharm.com | China | 39999 | 60 |
| Shanghai XR Chemical Technology Co., Ltd. | 021-31007982 18019432809 | info@xrpharma.com | China | 690 | 55 |
| Shanghai Haozhixiang Biotechnology Co., Ltd | 526763801 13301653310 | 526763801@qq.com | China | 9445 | 55 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6355 | 58 |
