2-CHLOROMETHYL-6-FLUOROPYRIDINE
- CAS No.
- 315180-16-6
- Chemical Name:
- 2-CHLOROMETHYL-6-FLUOROPYRIDINE
- Synonyms
- CHEMPACIFIC 38174;2-CHLOROMETHYL-6-FLUOROPYRIDINE;Pyridine, 2-(chloromethyl)-6-fluoro-;Pyridine, 2-(chloromethyl)-6-fluoro- (9CI)
- CBNumber:
- CB5306574
- Molecular Formula:
- C6H5ClFN
- Molecular Weight:
- 145.56
- MDL Number:
- MFCD07774124
- MOL File:
- 315180-16-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-(Chloromethyl)-6-fluoropyridine | 8139BB | 1g | $663 |
| 2-CHLOROMETHYL-6-FLUOROPYRIDINE 95.00% | HCH0003231 | 1G | $945.95 |
| 2-CHLOROMETHYL-6-FLUOROPYRIDINE 95.00% | HCH0003231 | 5G | $1855.51 |
| 2-(Chloromethyl)-6-fluoropyridine 97% | A123935 | 250mg | $181 |
| 2-(chloromethyl)-6-fluoropyridine 97% | CM171581 | 1g | $405 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
2-CHLOROMETHYL-6-FLUOROPYRIDINE price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | 8139BB | 2-(Chloromethyl)-6-fluoropyridine | 315180-16-6 | 1g | $663 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0003231 | 2-CHLOROMETHYL-6-FLUOROPYRIDINE 95.00% | 315180-16-6 | 1G | $945.95 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0003231 | 2-CHLOROMETHYL-6-FLUOROPYRIDINE 95.00% | 315180-16-6 | 5G | $1855.51 | 2021-12-16 | Buy |
| Ambeed | A123935 | 2-(Chloromethyl)-6-fluoropyridine 97% | 315180-16-6 | 250mg | $181 | 2021-12-16 | Buy |
| Chemenu | CM171581 | 2-(chloromethyl)-6-fluoropyridine 97% | 315180-16-6 | 1g | $405 | 2021-12-16 | Buy |
2-CHLOROMETHYL-6-FLUOROPYRIDINE Chemical Properties,Uses,Production
Synthesis
407-22-7
315180-16-6
Step A: Preparation of 2-chloromethyl-6-fluoropyridine To a solution of 2-fluoro-6-methylpyridine (0.23 mL, 2.2 mmol) in acetonitrile (5 mL) was sequentially added N-chlorosuccinimide (440 mg, 3.3 mmol), benzoyl peroxide (14 mg, 0.044 mmol) and glacial acetic acid (10 μL). The reaction mixture was heated at 85 °C with stirring for 4 h, followed by continued stirring for 18 h at room temperature. Upon completion of the reaction, the mixture was partitioned between ethyl acetate and water. The organic phase was washed sequentially with water and saturated saline and dried over anhydrous magnesium sulfate. The desiccant was removed by filtration and the filtrate was concentrated under reduced pressure to give the crude product. Purification of the crude product by normal phase column chromatography (eluent: ethyl acetate/heptane) afforded 2-chloromethyl-6-fluoropyridine as a colorless oil (240 mg, 75% yield).
References
[1] Patent: US2013/143906, 2013, A1. Location in patent: Paragraph 0309
[2] Patent: US2009/82403, 2009, A1. Location in patent: Page/Page column 94
[3] Patent: US2007/105904, 2007, A1. Location in patent: Page/Page column 93
2-CHLOROMETHYL-6-FLUOROPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
2-CHLOROMETHYL-6-FLUOROPYRIDINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5661 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Qingdao Dexin Chemical Co., Ltd | +86-15553333686 | 15553333686@qq.com | China | 3113 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Suzhou JingTong Pharmaceutical Co., Ltd. | 13675155016 | tongtf110@sina.com | China | 963 | 55 |
| ChengDu TongChuangYuan Pharmaceutical Co.Ltd | 028-83379370 13880556291 | tcy@tcypharm.com | China | 7218 | 58 |
| Nanijing m&m biotechnology Co. ,Ltd. | 025-87782433 18021532344 | 1345332203@qq.com | China | 4137 | 58 |
| Aikon International Limited | 025-58859352 18068836627 | sales01@aikonchem.com | China | 15083 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 52687 | 58 |
| Cool Pharm, Ltd | 021-58581007 18019463053 | sales@coolpharm.com | China | 5666 | 58 |
