ChemicalBook >> CAS DataBase List >>1-BENZOYL-3-PHENYL-2-THIOUREA
1-BENZOYL-3-PHENYL-2-THIOUREA
- CAS No.
- 4921-82-8
- Chemical Name:
- 1-BENZOYL-3-PHENYL-2-THIOUREA
- Synonyms
- usafk-1473;phenylbenzoylthiourea;1-Benzoyl-3-phenylthiourea;N-Phenyl-N'-benzoylthiourea;N-Benzoyl-N'-phenylthiourea;1-Benzoyl-3-phenyl(thiourea);1-BENZOYL-3-PHENYL-2-THIOUREA;1-benzoyl-3-phenyl-2-thio-ure;n-phenylthiocarbamoyl-benzamid;N-(Phenylthiocarbamoyl)benzamide
- CBNumber:
- CB5380011
- Molecular Formula:
- C14H12N2OS
- Molecular Weight:
- 256.32
- MDL Number:
- MFCD00022118
- MOL File:
- 4921-82-8.mol
Last updated:2023-05-04 15:16:43
| Melting point | 159 °C |
|---|---|
| Density | 1.290±0.06 g/cm3(Predicted) |
| storage temp. | -20° |
| solubility | Soluble in DMSO (greater than 50 mg/ml) or in Ethanol (up to 8 mg/ml). |
| form | solid |
| pka | 9.49±0.70(Predicted) |
| color | Off-white |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
| CAS DataBase Reference | 4921-82-8(CAS DataBase Reference) |
| FDA UNII | UAE2W88H3G |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H411-H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| HazardClass | IRRITANT |
| HS Code | 2930909899 |
1-BENZOYL-3-PHENYL-2-THIOUREA price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S505528 | 1-BENZOYL-3-PHENYL-2-THIOUREA Aldrich | 4921-82-8 | 1g | $179 | 2024-03-01 | Buy |
| Matrix Scientific | 056642 | 1-Benzoyl-3-phenyl-2-thiourea 98% | 4921-82-8 | 25g | $330 | 2021-12-16 | Buy |
| Oakwood | 018201 | 1-Benzoyl-3-phenyl-2-thiourea 98% | 4921-82-8 | 25g | $335 | 2021-12-16 | Buy |
| Matrix Scientific | 056642 | 1-Benzoyl-3-phenyl-2-thiourea 98% | 4921-82-8 | 1mg | $27 | 2021-12-16 | Buy |
| Oakwood | 018201 | 1-Benzoyl-3-phenyl-2-thiourea 98% | 4921-82-8 | 1g | $28 | 2021-12-16 | Buy |
1-BENZOYL-3-PHENYL-2-THIOUREA Chemical Properties,Uses,Production
Description
TM-2-51 (4921-82-8) is a highly potent and isozyme selective activator of recombinant HDAC8. Increases the activity of HDAC8 by a factor of 12 at 10 μM. No activation of other HDACs is observed. TM-2-51 rescues the activity of catalytically compromised HDAC8 mutants?in vitro.2
References
1) Singh?et al. (2011), Histone deacetylase activators: N-acetylthioureas as highly potent and isozyme selective activators for human histone deacetylase-8 on a fluorescent substrate; Bioorg. Med. Chem. Lett.,?21?5920 2) Decross?et al. (2014), Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders; ACS Chem. Biol.,?9?2157 3) Singh?et al. (2015),?Mechanism of N-acylthiourea Mediated Activation of Human Histone Deacetylase 8 (HDAC8) at Molecular and Cellular Levels; J. Biol. Chem.,?290?6607
1-BENZOYL-3-PHENYL-2-THIOUREA Preparation Products And Raw materials
1-BENZOYL-3-PHENYL-2-THIOUREA Suppliers
Global( 44)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11605 | 64 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35906 | 56 |
| Beijing FYF Chemicals Co., Ltd | 15318973357 | 1460285141@qq.com | China | 2947 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Wuhan Chemwish Technology Co.， Ltd | 027-67849912 | sales@chemwish.com | China | 9150 | 60 |
4921-82-8(1-BENZOYL-3-PHENYL-2-THIOUREA)Related Search:
N-BENZOYL-N'-(4-[(E)-2-PHENYLDIAZENYL]PHENYL)THIOUREA
1-BENZOYL-3-PHENYL-2-THIOUREA
SALOR-INT L308269-1EA
AURORA 3570
N-BENZOYL-N'-(4-NITROPHENYL)THIOUREA
AURORA 48
5-(([(4-CHLOROANILINO)CARBOTHIOYL]AMINO)CARBONYL)-2,1,3-BENZOXADIAZOL-1-IUM-1-OLATE
AURORA 2108
AURORA 7338
5-([(ANILINOCARBOTHIOYL)AMINO]CARBONYL)-2,1,3-BENZOXADIAZOL-1-IUM-1-OLATE
1of4
1-benzoyl-3-phenyl-2-thio-ure
n-phenylthiocarbamoyl-benzamid
phenylbenzoylthiourea
usafk-1473
1-Benzoyl-3-phenyl(thiourea)
1-Benzoyl-3-phenylthiourea
N-(Phenylthiocarbamoyl)benzamide
N-Benzoyl-N'-phenylthiourea
N-Phenyl-N'-benzoylthiourea
1-BENZOYL-3-PHENYL-2-THIOUREA
N-[(PHENYLAMINO)THIOXOMETHYL]-BENZAMIDE
N-[anilino(sulfanylidene)methyl]benzamide
Benzamide, N-[(phenylamino)thioxomethyl]-
N-(Phenylcarbamothioyl)benzamide
4921-82-8
C14H12N2OS