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1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE

1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE structure

CAS No.: 52099-72-6

Chemical Name:: 1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE

Synonyms: IFLAB-BB F0451-0304;TIMTEC-BB SBB006406;ISOPROPENYL-BENZIMID;Flibanserin Impurity 10;Domperidone Impurity 22;Domperidone Impurity 33;N-Isopropenyl-2-benzimidazolone;1-Isopropenyl-2-benzimidazolone;ISOPROPENYL-BENZIMIDAZOLIDINONE-2;2-BENZIMIDAZOLINONE,1-ISOPROPENYL

CBNumber:: CB5432958

Molecular Formula:: C10H10N2O

Molecular Weight:: 174.2

MDL Number:: MFCD00218253

MOL File:: 52099-72-6.mol

MSDS File:: SDS

Last updated:2025-09-25 17:15:13

Product description	Number	Pack Size	Price
1-Isopropenyl-2-benzimidazolidinone 97%	679402	5g	$84.48
1-Isopropenyl-2-benzimidazolidinone 97%	679402	1g	$41.1
1-Isopropenyl-2-benzimidazolidinone min. 98.0 %	I1127	5G	$73
1-Isopropenyl-2-benzimidazolidinone min. 98.0 %	I1127	25G	$218
1-Isopropenyl-2-benzimidazolidinone	7318AB	10g	$158
More product size

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1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE Properties

Melting point	120-124 °C
Boiling point	305.17°C (rough estimate)
Density	1.1455 (rough estimate)
refractive index	1.6300 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	11.72±0.30(Predicted)
form	Crystalline Powder
color	White to slightly cream
BRN	140587
InChI	InChI=1S/C10H10N2O/c1-7(2)12-9-6-4-3-5-8(9)11-10(12)13/h3-6H,1H2,2H3,(H,11,13)
InChIKey	XFASJWLBXHWUMW-UHFFFAOYSA-N
SMILES	C1(=O)N(C(C)=C)C2=CC=CC=C2N1
CAS DataBase Reference	52099-72-6(CAS DataBase Reference)
FDA UNII	ZD63KF82QK
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

Hazard statements

H301

Precautionary statements

Hazard Codes

Risk Statements

Safety Statements

RIDADR

UN 2810 6.1/PG 3

WGK Germany

HazardClass

6.1

HS Code

29339980

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	1
2		0

1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE price More Price(19)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	679402	1-Isopropenyl-2-benzimidazolidinone 97%	52099-72-6	5g	$84.48	2025-07-31	Buy
Sigma-Aldrich	679402	1-Isopropenyl-2-benzimidazolidinone 97%	52099-72-6	1g	$41.1	2023-06-20	Buy
TCI Chemical	I1127	1-Isopropenyl-2-benzimidazolidinone min. 98.0 %	52099-72-6	5G	$73	2025-07-31	Buy
TCI Chemical	I1127	1-Isopropenyl-2-benzimidazolidinone min. 98.0 %	52099-72-6	25G	$218	2025-07-31	Buy
AK Scientific	7318AB	1-Isopropenyl-2-benzimidazolidinone	52099-72-6	10g	$158	2021-12-16	Buy

Product number	Packaging	Price	Buy
679402	5g	$84.48	Buy
679402	1g	$41.1	Buy
I1127	5G	$73	Buy
I1127	25G	$218	Buy
7318AB	10g	$158	Buy

1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE Chemical Properties,Uses,Production

Chemical Properties

Off-White Crystalline Solid

Synthesis

141-97-9

95-54-5

52099-72-6

General procedure for the synthesis of 1,3-dihydro-1-(1-methylethynyl)-2H-benzimidazol-2-one from ethyl acetoacetate and o-phenylenediamine: 50 grams of o-phenylenediamine, 90 grams of ethyl acetoacetate, and 5 grams of sodium hydroxide were dissolved in 300 ml of o-xylene. The reaction was refluxed at 130°C for about 7 hours, during which time the water generated was removed by means of a water separator. Upon completion of the reaction, the reaction mixture was cooled to 80 °C and washed twice with 100 ml of water to remove water-soluble impurities. Subsequently, the mixture was cooled to 0 °C to allow the target product to precipitate as a white solid. The solid product was collected by filtration and dried to give 65 g of 1,3-dihydro-1-(1-methylethynyl)-2H-benzimidazol-2-one (DOM-2) in 94% yield.

References

[1] Patent: CN108129396, 2018, A. Location in patent: Paragraph 0022; 0023; 0033; 0034
[2] Bulletin des Societes Chimiques Belges, 1987, vol. 96, # 10, p. 787 - 792
[3] Patent: CN102816121, 2016, B. Location in patent: Paragraph 0022-0024
[4] Journal of Chemical Research - Part S, 1996, # 2, p. 92 - 93
[5] Russian Journal of Physical Chemistry A, 2015, vol. 89, # 5, p. 807 - 811

1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE Preparation Products And Raw materials

Raw materials

Ethyl acetoacetate o-Phenylenediamine o-Xylene Sodium hydroxide

Preparation Products

5,6-Dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione 2-Oxo-1-benzimidazolinebutyric Acid Imidazo[4,5,1-jk][1]benzazepin-2(1H)-one, 6-amino-4,5,6,7-tetrahydro-7-hydroxy- (hydrochloride) Flibanserin Hydrochloride 3-Isopropenyl-2-oxo-1-benzimidazolinebutyric Acid Ethyl Ester

1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE Suppliers

Global( 219)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13502	58
Nanjing Finetech Chemical Co., Ltd.	025-85710122 17714198479	sales@fine-chemtech.com	CHINA	885	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29850	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Shochem(Shanghai) Co.,Ltd	86-21-50800795	info@shochem.com	CHINA	288	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
Changzhou Carman Chemical Co., Ltd.	15061933924		CHINA	514	58
Shanghai Longyu Biotechnology Co., Ltd.	+8619521488211	info@longyupharma.com	China	2541	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Shanghai Yingrui Biopharma Co.,Ltd	21-33585366	export01@shyrchem.com	CHINA	1319	58

Supplier	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	58
Nanjing Finetech Chemical Co., Ltd.	55
career henan chemical co	58
Hubei xin bonus chemical co. LTD	58
Shochem(Shanghai) Co.,Ltd	58
Standardpharm Co. Ltd.	58
Changzhou Carman Chemical Co., Ltd.	58
Shanghai Longyu Biotechnology Co., Ltd.	58
Alchem Pharmtech,Inc.	58
Shanghai Yingrui Biopharma Co.,Ltd	58

View Lastest Price from 1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE 52099-72-6	US $1.00 / KG	1KG	99%	Customized	Career Henan Chemical Co

1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE
52099-72-6
US $1.00 / KG
99%
Career Henan Chemical Co

1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE Spectrum

1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE(52099-72-6)¹HNMR

52099-72-6(1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE)Related Search:

1,3-dihydro-4-methyl-2H-1,5-benzodiazepin-2-one Flibanserin-d4 Flibanserin 1-ACETYL-2-METHYLBENZIMIDAZOLE 1-(3-Trifluoromethylphenyl)piperazine hydrochloride

1-(prop-1-en-2-yl)-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1H-benzo[d]imidazol-2(3H)-one 3,3'-(ethane-1,2-diyl)bis(1-(2-chloroethyl)-1H-benzo[d]imidazol-2(3H)-one) 1,2-bis(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethane Flibanserin Hydrochloride 4-methyl-1H-benzo[b][1,4]diazepin-2(3H)-one

1,3-bis(2-chloroethyl)benzimidazolin-2-one DROPERIDOL 1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE 1,3-DIHYDRO-1-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-2H-BENZIMIDAZOLE-2-ONE 1-[1-(CYCLOOCTYLMETHYL)-1,2,3,6-TETRAHYDRO-5-(HYDROXYMETHYL)-4-PYRIDINYL]-3-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE HYDROCHLORIDE

2H-BENZIMIDAZOL-2-ONE, 1,3-DIHYDRO-1-(2-HYDROXYETHYL)-3-(1-METHYLETHENYL)- 4-(3-ISOPROPENYL-2-OXO-2,3-DIHYDRO-1H-1,3-BENZIMIDAZOL-1-YL)BUTANOIC ACID 1-(1-BENZYL-1,2,3,6-TETRAHYDRO-PYRIDIN-4-YL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE

1of4

3-Isopropenyl-1H-benzimidazole-2(3H)-one 1-(prop-1-en-2-yl)-1H-benzo(d)imidazol-2(3H)-one 1-Isopropyl-2-benzimidazolidinone,99% N-Isopropenyl-2-benzimidazolone 1-Isopropyl-2-benzimidazolidinone, 99% 2H-BenziMidazol-2-one, 1,3-dihydro-1-(1-Methylethenyl)- 1-(2-Propenyl)-1,3-dihydro-benziMidazol-2H-one 1-lsopropenyl-2-benziMidazolidinone -(2-PROPENYL)-2-BENZIMIDAZOLIDINONE 1-(2-PROPENYL)-2-BENZIMIDAZOLIDINONE 1,3-DIHYDRO-1-(1-METHYLETHENYL)-2H-BENZIMIDAZOLE-2-ONE 1-ISOPROPENYL-1,3-DIHYDRO-2H-1,3-BENZIMIDAZOL-2-ONE 1-ISOPROPENYL-2-BENZIMIDAZOLIDINONE ISOPROPENYL-BENZIMIDAZOLIDINONE-2 IFLAB-BB F0451-0304 TIMTEC-BB SBB006406 1-(methylvinyl)-1H-benzimidazol-2(3H)-one 1-Isopropenyl-1H-benzimidazol-2(3H)-one 1,3-dihydro-1-(1-methylvinyl)-2H-benzimidazol-2-one 1,3-Dihydro-1-(1-Methylethenyl)-2H-Benzimidazol-2-One 1,3-Dihydro-1-(1-methylvinyl)-2H-benzimidazol-2-on 1,3-DIHYDRO-1-(1-METHYLETHENYL)-2H-BENZIMIDAZOLE-2-ONE 99% 2-BENZIMIDAZOLINONE,1-ISOPROPENYL 2H-Benzimidazol-2-one,1,3-dihydro-1-(1-methylethenyl)-(9CI) 1-Isopropenyl-2-benzimidazolidinone, 98+% 1,3-Dihydro-1-(1-methylethenyl)-2H-benzimidazole-2-one, 1-(2-Propenyl)-2-benzimidazolidinone 1,3-dihydro-1 - (1-methylethynyl) - 2h-benzimidazole-2-one 1-(prop-1-en-2-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one Flibanserin Impurity 10 1,3- dihydro-1-(1-methylacetylene)-2H-benzimidazole-2-ketone ISOPROPENYL-BENZIMID 1-(2-Propen-2-yl)-2-benzimidazolidinone 1-Isopropenyl-2-benzimidazolone Domperidone Impurity 22 1-(porp-1-en-2-yl)-1H-benzo{d}-imidazol-2-(3H)-one Domperidone Impurity 33 52099-72-6 52099-72-9 72798-66-8 Aromatics Aromatics Compounds Imidaxoles BENZIMIDAZOLE