5-Chlorosalicylaldehyde
- CAS No.
- 635-93-8
- Chemical Name:
- 5-Chlorosalicylaldehyde
- Synonyms
- 5-CHLORO-2-HYDROXYBENZALDEHYDE;orosaL;AKOS 90774;5-Cl-salicylal;5-chloro-salicylal;TIMTEC-BB SBB004013;5-Chlorosalicylaldeh;5-Chlorosalicyldehyde;5-Chlorosalicyladehyde;5-chorosalicylaldehyde
- CBNumber:
- CB5465327
- Molecular Formula:
- C7H5ClO2
- Molecular Weight:
- 156.57
- MDL Number:
- MFCD00003331
- MOL File:
- 635-93-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 100-102 °C(lit.) |
|---|---|
| Boiling point | 217.69°C (rough estimate) |
| Density | 1.2683 (rough estimate) |
| refractive index | 1.5812 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 7.73±0.18(Predicted) |
| form | Crystalline Powder |
| color | White to very slightly yellow |
| Sensitive | Air Sensitive |
| BRN | 636632 |
| InChI | InChI=1S/C7H5ClO2/c8-6-1-2-7(10)5(3-6)4-9/h1-4,10H |
| InChIKey | FUGKCSRLAQKUHG-UHFFFAOYSA-N |
| SMILES | C(=O)C1=CC(Cl)=CC=C1O |
| LogP | 2.570 (est) |
| CAS DataBase Reference | 635-93-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 4GCC8ZKM3O |
| NIST Chemistry Reference | 5-Chloro-2-hydroxy benzaldehyde(635-93-8) |
| EPA Substance Registry System | Benzaldehyde, 5-chloro-2-hydroxy- (635-93-8) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335-H400 | |||||||||
| Precautionary statements | P273-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-24/25-36/37/39 | |||||||||
| RIDADR | UN2811/6.1/PG III | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VN5450000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 9 | |||||||||
| HS Code | 29130000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Aquatic Acute 1 Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| Limited Quantities | 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
5-Chlorosalicylaldehyde price More Price(93)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 447706 | 5-Chlorosalicylaldehyde 98% | 635-93-8 | 5g | $63.9 | 2026-04-30 | Buy |
| Sigma-Aldrich | 447706 | 5-Chlorosalicylaldehyde 98% | 635-93-8 | 25g | $81.5 | 2026-04-30 | Buy |
| TCI Chemical | C0738 | 5-Chlorosalicylaldehyde >98.0%(GC)(T) | 635-93-8 | 5g | $17 | 2026-04-30 | Buy |
| TCI Chemical | C0738 | 5-Chlorosalicylaldehyde >98.0%(GC)(T) | 635-93-8 | 25g | $52 | 2026-04-30 | Buy |
| Usbiological | 436253 | 5-Chlorosalicyaldehyde | 635-93-8 | 2.5g | $368 | 2026-06-03 | Buy |
5-Chlorosalicylaldehyde Chemical Properties, Uses, Production
Chemical Properties
white to very slightly yellow crystalline powder
Uses
5-Chlorosalicyaldehyde is a useful synthetic intermediate and a key precursor to a variety chelating agents.5-Chlorosalicyaldehyde is used to synthesize imine resveratrol (R150000) derivatives as multi-targeted agents against Alzheimer's disease.
Synthesis Reference(s)
Synthetic Communications, 20, p. 609, 1990 DOI: 10.1080/00397919008244911
Tetrahedron Letters, 15, p. 3463, 1974
Purification Methods
Steam distil it, then crystallise it from aqueous EtOH or *C6H6 (m 100o). It forms complexes with Cu2+ and Fe2+ . [Beilstein 8 H 53, 8 II 45, 8 III 181, 8 IV 224.]
5-Chlorosalicylaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhangjiagang Free Trade Zone Kailite Chemical Co., Ltd. | 18606289633 15862625988 | sales@clentchem.com | China | 244 | 60 |
| Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. | 13396369453 18678026865 | sdfantai@163.com | China | 904 | 58 |
| Hubei Chenghai Chemical Co., Ltd | 027-59220433 18327245847 | 1400838877@qq.com | China | 9507 | 58 |
| Shaanxi Renheng Yide Biotechnology Co., Ltd | 15319940549 15319940549 | 241757027@qq.com | China | 150 | 58 |
| Shandong Xinying Shun New Materials Co., Ltd | 0531-13220555910 15168808500 | lijinbo112@163.com | China | 510 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44852 | 61 |
View Latest Price from 5-Chlorosalicylaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-28 | 5-Chlorosalicylaldehyde
635-93-8
|
$20.60 | 1KG | 99% | 5000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
![]() |
2026-02-02 | 5-Chlorosalicylaldehyde
635-93-8
|
10mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd | ||
![]() |
2025-06-27 | 5-Chlorosalicylaldehyde
635-93-8
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd |
-

- 5-Chlorosalicylaldehyde
635-93-8
- $20.60
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-

- 5-Chlorosalicylaldehyde
635-93-8
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
-

- 5-Chlorosalicylaldehyde
635-93-8
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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