ChemicalBook >> CAS DataBase List >>OXYMORPHONE HCL NARCOTIC ANALGESIC
OXYMORPHONE HCL NARCOTIC ANALGESIC
- CAS No.
- 357-07-3
- Chemical Name:
- OXYMORPHONE HCL NARCOTIC ANALGESIC
- Synonyms
- OxyMorphone HCl;numorphanhydrochloride;oxymorphone hydrochloride;oxymorphinonehydrochloride;OXYMORPHONE HCL NARCOTIC ANALGESIC;4,5-alpha-epoxy-3,14-dihydroxy-17-methylmorphinan-6-onehydrochloride;3,14-dihydroxy-4,5-alpha-epoxy-17-methyl-morphinan-6-onhydrochloride;(5alpha)-4,5-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride;morphinan-6-one,4,5-epoxy-3,14-dihydroxy-17-methyl-,hydrochloride,(5-alpha;Morphinan-6-one,4,5-epoxy-3,14-dihydroxy-17-Methyl-, hydrochloride (1:1), (5a)-
- CBNumber:
- CB5504053
- Molecular Formula:
- C17H21ClNO4
- Molecular Weight:
- 338.80594
- MDL Number:
- MOL File:
- 357-07-3.mol
Last updated:2023-06-08 09:03:01
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml |
|---|---|
| form | A crystalline solid |
| color | Yellowish-tan powder |
| Stability | Hygroscopic |
| NCI Dictionary of Cancer Terms | oxymorphone hydrochloride |
| FDA UNII | 5Y2EI94NBC |
| NCI Drug Dictionary | oxymorphone hydrochloride |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H310-H302-H330 | |||||||||
| Precautionary statements | P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501-P264-P270-P301+P312-P330-P501 | |||||||||
| RIDADR | 3249 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| Toxicity | LD50 orl-mus: 402 mg/kg THERAP15,1208,60 | |||||||||
| NFPA 704 |
|
OXYMORPHONE HCL NARCOTIC ANALGESIC Chemical Properties,Uses,Production
Uses
Analgesic (narcotic).
Definition
ChEBI: Oxymorphone hydrochloride is a member of phenanthrenes.
brand name
Numorphan (Endo); Opana (Endo).
Clinical Use
Oxymorphone is a potent μ agonist (10 times greater than morphine) that is used to treat severe pain. It is used by intramuscular, subcutaneous, intravenous, and rectal routes of administration. The intramuscular dose of oxymorphone (1 mg) has a half-life of 3 to 4 hours. It is a Schedule II drug. Oxymorphone, because of its 14-hydroxy group, has low antitussive activity.
Safety Profile
Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx and HCl.
OXYMORPHONE HCL NARCOTIC ANALGESIC Preparation Products And Raw materials
Raw materials
Preparation Products
357-07-3(OXYMORPHONE HCL NARCOTIC ANALGESIC)Related Search:
OXYMORPHONE HCL NARCOTIC ANALGESIC
3,14-dihydroxy-4,5-alpha-epoxy-17-methyl-morphinan-6-onhydrochloride
4,5-alpha-epoxy-3,14-dihydroxy-17-methylmorphinan-6-onehydrochloride
morphinan-6-one,4,5-epoxy-3,14-dihydroxy-17-methyl-,hydrochloride,(5-alpha
numorphanhydrochloride
oxymorphinonehydrochloride
(5alpha)-4,5-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride
OxyMorphone HCl
Morphinan-6-one,4,5-epoxy-3,14-dihydroxy-17-Methyl-, hydrochloride (1:1), (5a)-
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one hydrochloride
oxymorphone hydrochloride
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one:hydrochloride
357-07-3