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Cinnamonitrile

Flavors Chemical properties Antibacterial effects Application Preparation
Cinnamonitrile
Cinnamonitrile
CAS No.
1885-38-7
Chemical Name:
Cinnamonitrile
Synonyms
CINNAMALVA;naMonitrile;Rou Guijing;AKOS B004065;Ciamonitrile;Cinnamonitril;CINNAMONITRILE;STYRYL CYANIDE;CINNAMYL NITRILE;Cinnamonitrile c&t
CBNumber:
CB5729719
Molecular Formula:
C9H7N
Formula Weight:
129.16
MOL File:
1885-38-7.mol

Cinnamonitrile Properties

Melting point:
18-20 °C(lit.)
Boiling point:
254-255 °C(lit.)
Density 
1.028 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.601(lit.)
Flash point:
>230 °F
storage temp. 
Store at <= 20°C.
form 
Liquid
color 
Clear colorless to yellow
Water Solubility 
insoluble
Sensitive 
Air & Light Sensitive
CAS DataBase Reference
1885-38-7(CAS DataBase Reference)
NIST Chemistry Reference
2-Propenenitrile, 3-phenyl-, (E)-(1885-38-7)
EPA Substance Registry System
2-Propenenitrile, 3-phenyl-, (2E)-(1885-38-7)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
RIDADR  3276
WGK Germany  3
RTECS  UD1440000
9
TSCA  Yes
HS Code  29269095
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P501 Dispose of contents/container to..…

Cinnamonitrile price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.20349 Cinnamonitrile 1885-38-7 1EA $62.5 2017-11-08 Buy
Sigma-Aldrich 8.20349 Cinnamonitrile 1885-38-7 2EA $190 2017-11-08 Buy
TCI Chemical C0361 Cinnamonitrile >95.0%(GC) 1885-38-7 25g $88 2017-11-08 Buy
Alfa Aesar B25503 Cinnamonitrile, 97%, predominantly trans 1885-38-7 25g $43.6 2017-11-08 Buy
Alfa Aesar B25503 Cinnamonitrile, 97%, predominantly trans 1885-38-7 100g $137 2017-11-08 Buy

Cinnamonitrile Chemical Properties,Uses,Production

Flavors

Cinnamonitrile is also  known as styrene cyanide, is an excellent synthetic spice,it has a strong spicy aroma like cinnamon and floral nuances, colorless or pale yellow viscous liquid, it is chemically stable, light, heat or acid, alkaline etching can not make it change. There are no toxic side effects on the human body, there is no stimulation in contact with skin ,there are no allergic reactions, compared with cinnamic aldehyde, cinnamonitrile has the stronger ability through the hair, the aroma is strong and lasts for a long time, potential   skin irritation and toxicity are smaller than  cinnamic aldehyde,it is the ideal substitute for cinnamon oil and cinnamic aldehyde,it can be used in daily chemical flavor formula,it is mainly used for soap flavor and fragrance detergent formulations, the amount is less than 2%. IFRA has no restrictions. Since cinnamonitrile has a unique chemical structure,it can occur Friedel, addition, reduction, hydrolysis reactions,it is also widely be used  in the pharmaceutical, fine chemical industry  . According to the information provided by RIFM, acute toxicity data of cinnamonitrile: oral LD504.15g/kg (rat), skin test LD50> 5g/kg (rabbit). Cinnamonitrile can be made by condensation of acetonitrile with benzaldehyde in the presence of potassium hydroxide solution  ; or it can be made by the  first transformation of cinnamaldehyde  into oxime, then  by the dehydration following.

Chemical properties

Light transparent pale yellow liquid with a strong, warm spicy fragrance.

Antibacterial effects

Nanjing University Department of Biology and the Institute of Hydrobiology of the Chinese Academy of Sciences teachers measured the inhibitory effects of   plant pathogens Altornaria tenuis Nees and Rhizopus nigricans on their own separate identification , skin addiction germs Epidermophyton floccosum, Trichophytoa gypsoum, Trichophyton rubrum, Microsporum gypseum, as well as 22 kinds of mold (  18 kinds of common food, fruits and other mold rot fungus, four kinds of human shallow filamentous fungus), the results show that  cinnamonitrile has a high nitrile  antimicrobial effect,it has the role of antibiotics, but  it is not an antibiotic,its mold inhibition effect is good, it has broad  antibacterial spectrum , and anthelmintic effect. Experiments show that the breeding of bacteria in the production process needs folic acid to participate in  , cinnamonitrile  structure is similar to PABA, they are competitive in binding with dihydrofolate synthase, which inhibits the activity of  dihydrofolate synthase, impeding dihydrofolate synthesis, thus affecting the synthesis of folic acid, inhibiting bacterial growth propagation; and it can interfere with the synthesis of some bacteria, and the synthesis of the enzyme needed for cell division to inhibit and impact the synthesis of bacterial RNA , which reduces the permeability of the cell membrane thus affects the normal metabolism of bacteria, resulting in death, so bactericidal effect  are more thorough . What is more amazing  is that the human body does not produce Cinnamonitrile  dependence, it can eliminate bacteria tribes, but it will not break the constraints  relationship between bacteria and thus does not produce resistance. Cinnamonitrile  itself is a spice, there are no toxic side effects on the human body, in contact with skin no stimulation, no allergic reactions. Experts said excitedly,that with deepening study of the cinnamonitrile  antibacterial  aspect  , cinnamonitrile is expected to completely replace antibiotics, and become the "Terminator"of antibiotics.

Application

Preparation

Cinnamic aldehyde reacts with hydroxylamine hydrochloride in the presence of pyridine by the addition-elimination reaction to produce aldehyde oxime, then it boils with toluene azeotropic and after dehydration to generate  cinnamonitrile.

Chemical Properties

clear colourless to yellow liquid

Uses

The parent compound whose derivatives can be applied as corrosion inhibitors for API J55 steel.

Cinnamonitrile Preparation Products And Raw materials

Raw materials

Preparation Products


Cinnamonitrile Suppliers

Global( 143)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19954 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3218 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32765 55
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 saleschina@alfa-asia.com China 30308 84
Wuhan lenmaike Industrial Co., Ltd. 13396062449
027-83916065 279115899@qq.com China 278 58
Shanghai Boyle Chemical Co., Ltd. Mr Qiu:021-50182298(Demestic market) Miss Xu:021-50180596(Abroad market)
+86-21-57758967 sales@boylechem.com China 2221 55
MedicalChem(Yancheng)Manuf.Co.,Ltd +86-515-84383180
+86-515-84383182 sales@medicalchem.com China 80 69
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40399 62
future industrial shanghai co., ltd 400-0066-400;021-60496031
021-55660885 sales@jonln.com China 2042 65

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