Ancarolol
- CAS No.
- 75748-50-4
- Chemical Name:
- Ancarolol
- Synonyms
- Ancarolol;N-[2-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl]furan-2-carboxamide;N-[2-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-2-furancarboxamide;2-Furancarboxamide, N-[2-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-
- CBNumber:
- CB61117659
- Molecular Formula:
- C18H24N2O4
- Molecular Weight:
- 332.39
- MDL Number:
- MFCD00868358
- MOL File:
- 75748-50-4.mol
| Boiling point | 433.7±45.0 °C(Predicted) |
|---|---|
| Density | 1.183±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| pka | 12.26±0.70(Predicted) |
| FDA UNII | 00EED65INL |
Ancarolol Chemical Properties,Uses,Production
Originator
Ancarolol,ZYF Pharm Chemical
Manufacturing Process
A mixture of 23 g of 2'-(2,3-epoxypropoxy)-furan-2-carboxylic acid anilide, 7.3 g of t-butylamine and 50 ml of isopropanol is boiled under reflux for 10 hours. On cooling, 2'-(2-hydroxy-3-t-butylaminopropoxy)-furan-2-carboxylic acid anilide (ancarolol) crystallizes out from the solution. The chromatographically pure base is obtained in the form of a white solid of melting point 112°-113°C by recrystallization from ethyl acetate. The yield is 12 g. The colorless, crystalline base is dissolved in alcohol, alcoholic HCl is added and the hydrochloride is induced to crystallize by adding ether dropwise. After isolation, the salt is recrystallized again from ethanol. This gives 10 g of the hydrochloride, melting point 189°-191°C.
Therapeutic Function
Beta-adrenergic blocker
Ancarolol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3238 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 9946 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223 | psaitong@jm-bio.com | China | 29834 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |