ChemicalBook >> CAS DataBase List >>Trimethylamine N-oxide

Trimethylamine N-oxide

Trimethylamine N-oxide structure

CAS No.: 1184-78-7

Chemical Name:: Trimethylamine N-oxide

Synonyms: TMAO;Trimethylamine oxide;N,N-dimethylmethanamine oxide;trimethyloxamine;Trimetlylamine Oxide;Triox;TMANO Anhydrous;TRIMETHYLAMINOXIDE;rimethylamineN-oxide;TRIMETHYLAMINE N-OXIDE

CBNumber:: CB6140124

Molecular Formula:: C3H9NO

Molecular Weight:: 75.11

MDL Number:: MFCD00082441

MOL File:: 1184-78-7.mol

MSDS File:: SDS

Last updated:2023-12-26 17:34:35

Request For Quotation

Trimethylamine N-oxide Properties

Melting point	220-222 °C (lit.)
Boiling point	133.8°C (rough estimate)
Density	0.9301 (rough estimate)
vapor pressure	23.5Pa at 20℃
refractive index	1.4698 (estimate)
FEMA	4245 \| TRIMETHYLAMINE OXIDE
storage temp.	Hygroscopic, Room Temperature, under inert atmosphere
solubility	Chloroform, DMSO, Methanol (Slightly)
pka	4.65(at 25℃)
form	Solid
color	Pale Yellow
Odor	odorless
Water Solubility	793g/L at 24.5℃
Merck	14,9711
JECFA Number	1614
Stability	Hygroscopic
LogP	-2.79
Substances Added to Food (formerly EAFUS)	TRIMETHYLAMINE OXIDE
EWG's Food Scores	1
FDA UNII	FLD0K1SJ1A
EPA Substance Registry System	Methanamine, N,N-dimethyl-, N-oxide (1184-78-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H332

Precautionary statements

P261-P264-P270-P271-P301+P312-P304+P340+P312

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-37/39

WGK Germany

HS Code

2904.20.5000

NFPA 704

	0
2		0

Trimethylamine N-oxide price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	317594	Trimethylamine N-oxide 95%	1184-78-7	1g	$76.9	2024-03-01	Buy
Sigma-Aldrich	317594	Trimethylamine N-oxide 95%	1184-78-7	5g	$163	2024-03-01	Buy
TCI Chemical	T1362	Trimethylamine N-Oxide Anhydrous >95.0%(T)	1184-78-7	1g	$43	2024-03-01	Buy
TCI Chemical	T1362	Trimethylamine N-Oxide Anhydrous >95.0%(T)	1184-78-7	5g	$143	2024-03-01	Buy
Cayman Chemical	17354	Trimethylamine N-oxide ≥95%	1184-78-7	500mg	$32	2024-03-01	Buy

Product number	Packaging	Price	Buy
317594	1g	$76.9	Buy
317594	5g	$163	Buy
T1362	1g	$43	Buy
T1362	5g	$143	Buy
17354	500mg	$32	Buy

Trimethylamine N-oxide Chemical Properties,Uses,Production

Description

Trimethylamine N-oxide (TMAO) is a metabolite of choline, phosphatidylcholine, and L-carnitine . It is formed by gut microbiota-mediated metabolism of choline, phosphatidylcholine, and L-carnitine to TMA followed by oxidation of TMA by flavin-containing monooxygenase 3 (FMO3) in the liver. Dietary administration of TMAO (0.12% w/w) increases renal tubulointerstitial fibrosis, collagen deposition, and Smad3 phosphorylation in mice and increases aortic lesion area in atherosclerosis-prone ApoE^-/- mice. Plasma levels of TMAO are elevated in patients with chronic kidney disease and decreased in patients with active, compared with inactive, ulcerative colitis. Elevated plasma levels of TMAO are associated with increased risk of cardiovascular disease.

Chemical Properties

Colorless to yellow solid; odorless.

Chemical Properties

White crystalline powder

Uses

Trimethylamine?N-oxide can be used:

As a demetallation?and decarbonylation?reagent for organometallic compounds.
To prepare azomethine ylide by reaction with lithium di-isopropylamide. This, in turn, may be reacted with simple alkenes to obtain corresponding pyrrolidines.
To mediate the conversion of thiols to disulfides.

Definition

ChEBI: An N-oxide derived from triethylamine.

General Description

Trimethylamine?N-oxide is an organic compound that belongs to the class of amine oxides. It is generally found in the tissues of marine organisms, wherein it helps protect them from harsh conditions like salinity, hydrostatic pressure, temperature, and high urea.

Flammability and Explosibility

Not classified

Trimethylamine N-oxide synthesis

Synthesis of Trimethylamine N-oxide from Trimethylamine N-oxide dihydrate

Trimethylamine N-oxide Preparation Products And Raw materials

Raw materials

Hydrogen peroxide Toluene Trimethylamine

Preparation Products

N,N'-Dimethylpiperazine 2-DIMETHYLAMINOMETHYLPHENOL (CONTAINS PHENOL) (1-methylpyrrolidin-3-yl)methanol

Trimethylamine N-oxide Suppliers

Global( 161)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58

View Lastest Price from Trimethylamine N-oxide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-12-26	Trimethylamine N-oxide 1184-78-7	US $0.00-0.00 / kg	1kg	99%	500000kg	Hebei Kingfiner Technology Development Co.Ltd
2022-08-18	Trimethylamine N-oxide 1184-78-7	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2019-07-06	TRIMETHYLAMINE N-OXIDE HYDROCHLORIDE 1184-78-7	US $8.80 / KG	1KG	97%-99%	100kg	Career Henan Chemical Co

Trimethylamine N-oxide
1184-78-7
US $0.00-0.00 / kg
99%
Hebei Kingfiner Technology Development Co.Ltd

Trimethylamine N-oxide
1184-78-7
US $1.10 / g
99.00%
Dideu Industries Group Limited

TRIMETHYLAMINE N-OXIDE HYDROCHLORIDE
1184-78-7
US $8.80 / KG
97%-99%
Career Henan Chemical Co

Trimethylamine N-oxide Spectrum

Trimethylamine N-oxide(1184-78-7)MS Trimethylamine N-oxide(1184-78-7)¹HNMR Trimethylamine N-oxide(1184-78-7)¹³CNMR Trimethylamine N-oxide(1184-78-7)IR1 Trimethylamine N-oxide(1184-78-7)IR2

1184-78-7(Trimethylamine N-oxide)Related Search:

TRIMETHYLAMINE OXIDE DIHYDRATE Ammothamnine CLOZAPINE N-OXIDE Trimethylamine N-oxide N,N-DIMETHYLOCTYLAMINE-N-OXIDE

4-Methylmorpholine N-oxide LDAO DDAO 4-Methylmorpholine N-oxide monohydrate SCOPOLAMINE N-OXIDE HYDROBROMIDE

DIMETHYLSTEARYLAMINE OXIDE MYRISTYL DIMETHYLAMINE OXIDE Trimethylamine isatidine ATROPINE N-OXIDE HYDROCHLORIDE

2,2'-(BENZYLIMINO)-DIETHANOL N-OXIDE TRIETHYLAMINE N-OXIDE CODEINE N-OXIDE

1of4

n,n-dimethyl-methanaminn-oxide Triox TRIMETHYLAMINE N-OXIDE TRIMETHYLAMINE OXIDE HYDROCHLORIDE TRIMETHYLAMINE N-OXIDE HYDROCHLORIDE trimethyl-oxido-ammonium TRIMETHYLAMINOXIDE Trimethylamine N-Oxide Anhydrous Trimethylamine N-oxide,98% Trimethylamine N-oxide,TMANO TriMethylaMine N-oxide 98% Trimethylamine N-Oxide Anhydrous N,N-Dimethylmethanamine N-oxide Methanamine,N,N-dimethyl-,N-oxide TMANO Anhydrous rimethylamineN-oxide Trimethylamine N-oxide ISO 9001：2015 REACH Trimethylamine Oxide (TMAO) trimethylamine N-oxide(1184-78-7) TMAO Trimethylamine oxide trimethyloxamine Trimetlylamine Oxide N,N-dimethylmethanamine oxide 1184-78-7 Others Synthetic Reagents Oxidation Oxidation Synthetic Organic Chemistry