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IEM 1460
- CAS No.
- 121034-89-7
- Chemical Name:
- IEM 1460
- Synonyms
- IEM 1460;5-(1-adamantylmethylamino)pentyl-trimethylazanium:bromide:hydrobromide;N,N,H,-Trimethyl-5-[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]-1-pentanaminiumbromidehydrobromide;N,N,N-TRIMETHYL-5-[(TRICYCLO[3.3.1.13,7]DEC-1-YLMETHYL)AMINO]-1-PENTANAMINIUMBROMIDE HYDROBROMIDE
- CBNumber:
- CB6148913
- Molecular Formula:
- C19H38Br2N2
- Molecular Weight:
- 454.34
- MDL Number:
- MFCD09878250
- MOL File:
- 121034-89-7.mol
Last updated:2023-06-30 15:45:59
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H315 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
IEM 1460 price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 15623 | IEM 1460 ≥98% | 121034-89-7 | 10mg | $106 | 2024-03-01 | Buy |
| Cayman Chemical | 15623 | IEM 1460 ≥98% | 121034-89-7 | 50mg | $388 | 2024-03-01 | Buy |
| Tocris | 1636 | IEM1460 ≥98%(HPLC) | 121034-89-7 | 50 | $526 | 2021-12-16 | Buy |
| Tocris | 1636 | IEM1460 ≥98%(HPLC) | 121034-89-7 | 10 | $125 | 2021-12-16 | Buy |
| TRC | I942010 | IEM1460 | 121034-89-7 | 10mg | $275 | 2021-12-16 | Buy |
IEM 1460 Chemical Properties,Uses,Production
Description
IEM 1460 is an adamantine derivative that blocks both AMPA-
Uses
IEM 1460 is an Adamantane derivative and open-channel blocker of AMPA currents.
Biological Activity
Voltage-dependent open-channel blocker of AMPA receptors. Displays selectivity between subtypes, blocking GluR2 subunit-lacking (Ca 2+ -permeable) receptors more potently than GluR2-containing receptors (IC 50 values are 2.6 and 1102 μ M respectively). Also blocks NMDA receptor-mediated currents. Anticonvulsant in vivo .
storage
Room temperature (desiccate)
IEM 1460 Preparation Products And Raw materials
Raw materials
Preparation Products
IEM 1460 Suppliers
Global( 45)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 18768175414 | gaojun@univ-bio.com | China | 24998 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 18779 | 58 |
121034-89-7(IEM 1460)Related Search:
IEM 1460
N,N,N-TRIMETHYL-5-[(TRICYCLO[3.3.1.13,7]DEC-1-YLMETHYL)AMINO]-1-PENTANAMINIUMBROMIDE HYDROBROMIDE
N,N,H,-Trimethyl-5-[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]-1-pentanaminiumbromidehydrobromide
5-(1-adamantylmethylamino)pentyl-trimethylazanium:bromide:hydrobromide
121034-89-7
C19H37N2BrHBr
Selective inhibitor of a subtype of AMPA receptors (Ca2+ permeable, lacking GluR2 subunits); tool for functionally discriminating between AMPA receptors of different subunit composition
Ligand-Gated Ion Channels
Ion Channels
Ionotropic Glutamate Receptor Modulators
BioChemical
Cell Biology
Cell Signaling and Neuroscience
Glutamate receptor