C8-HSL
- CAS No.
- 147852-84-4
- Chemical Name:
- C8-HSL
- Synonyms
- OHL;C8-HSL;Octanoyl-L-hoMoserine lactone;(3R)-3-(2-Oxononyl)Oxolan-2-One;N-OCTANOYL-L-HOMOSERINE LACTONE;N-[(3S)-2-oxooxolan-3-yl]octanamide;(S)-N-(2-Oxotetrahydrofuran-3-yl)octanamide;C8-HSL, OHL, N-Octanoyl-L-hoMoserine lactone;N-Octanoyl-L-homoserine lactone >=96% (HPLC);N-[(3S)-Tetrahydro-2-oxo-3-furanyl]octanamide
- CBNumber:
- CB62456373
- Molecular Formula:
- C12H21NO3
- Molecular Weight:
- 227.3
- MDL Number:
- MFCD11113139
- MOL File:
- 147852-84-4.mol
- MSDS File:
- SDS
| Melting point | 134-135 °C |
|---|---|
| Boiling point | 448.1±34.0 °C(Predicted) |
| Density | 1.04±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMF: 25 mg/ml; DMF:PBS(pH7.2) 1:2: 0.3 mg/ml; DMSO: 20 mg/ml |
| form | A crystalline solid |
| pka | 14.83±0.20(Predicted) |
| optical activity | [α]/D -28±3°, c = 0.2 in methanol |
| BRN | 8148282 |
C8-HSL price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 44558 | N-Octanoyl-L-homoserine lactone ≥96% (HPLC) | 147852-84-4 | 10mg | $166 | 2024-03-01 | Buy |
| Sigma-Aldrich | 44558 | N-Octanoyl-L-homoserine lactone ≥96% (HPLC) | 147852-84-4 | 50mg | $776 | 2024-03-01 | Buy |
| Cayman Chemical | 10011199 | N-octanoyl-L-Homoserine lactone ≥98% | 147852-84-4 | 5mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 10011199 | N-octanoyl-L-Homoserine lactone ≥98% | 147852-84-4 | 10mg | $84 | 2024-03-01 | Buy |
| Cayman Chemical | 10011199 | N-octanoyl-L-Homoserine lactone ≥98% | 147852-84-4 | 25mg | $193 | 2024-03-01 | Buy |
C8-HSL Chemical Properties,Uses,Production
Uses
Octanoyl-L-homoserine lactone is an active quorum sensing modulator first recognised in Yersinia pseudotuberculosis. Octanoyl-L-homoserine lactone and other acylhomoserine lactones have been detected in hundreds of bacterial species and, while the homologues vary between species and strains, the homoserine lactones are the major chemical modulators of within and between cell communication and regulation. The most significant variable defining the function of the homoserine lactone is the length of the acyl chain, with shorter chains displaying opposing actions to the longer chains.
General Description
N-Octanoyl-L-homoserine lactone (C8-HSL) is a N-acyl homoserine lactone (N-acyl-HSL). It is highly nonpolar.
Biochem/physiol Actions
N-Octanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, colonization, chemical defense and cell to cell communication among bacteria; for reviews see. AHLs are released as oligopeptides in Gram positive bacteria and as quorum signal in Gram negative bacteria. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs, and a research focus for the prevention of biofilm formation.
C8-HSL Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| R&D Scientific Inc. | +12266000236 | sales@rdscientific.com | Canada | 1245 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Adamas Reagent, Ltd. | 400-6009262 16621234537 | zhangsn@titansci.com | China | 14113 | 59 |
| Shanghai Leto Pharmatech Co.,Ltd. | 18016401466 | sales@letopharm.com | China | 219 | 58 |
| ChemStrong Scientific Co.,Ltd | 0755-66853366 13670046396 | sales@chem-strong.com | China | 17982 | 56 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15878 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |