5-Bromo-1H-benzimidazole
- CAS No.
- 4887-88-1
- Chemical Name:
- 5-Bromo-1H-benzimidazole
- Synonyms
- 6-bromo-1H-benzo[d]imidazole;5-BROMO-1H-BENZO[D]IMIDAZOLE;5-BROMO-1H-BENZOIMIDAZOLE;6-Bromobenzimidazole;5-BROMOBENZIMIDAZOLE;6-Bromobenzimidazole>5-BROMO-1H-BENZIMIDAZOLE;1H-BenziMidazole, 6-broMo-;5-broMo-1H-1,3-benzodiazole;5-Bromo-1H-benzimidazole 98%
- CBNumber:
- CB6280903
- Molecular Formula:
- C7H5BrN2
- Molecular Weight:
- 197.03
- MDL Number:
- MFCD00160001
- MOL File:
- 4887-88-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 130 °C |
|---|---|
| Boiling point | 417.4±18.0 °C(Predicted) |
| Density | 1.770±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 11.19±0.30(Predicted) |
| color | White to Yellow to Orange |
| InChI | InChI=1S/C7H5BrN2/c8-5-1-2-6-7(3-5)10-4-9-6/h1-4H,(H,9,10) |
| InChIKey | GEDVWGDBMPJNEV-UHFFFAOYSA-N |
| SMILES | C1NC2=CC(Br)=CC=C2N=1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38-36-22 | |||||||||
| Safety Statements | 22-26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2933998090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| NFPA 704 |
|
5-Bromo-1H-benzimidazole price More Price(82)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 702188 | 6-Bromo-1H-benzimidazole 97% | 4887-88-1 | 1g | $31.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | 702188 | 6-Bromo-1H-benzimidazole 97% | 4887-88-1 | 5g | $126 | 2026-04-30 | Buy |
| TCI Chemical | B4458 | 6-Bromobenzimidazole >98.0%(T) | 4887-88-1 | 1g | $36 | 2026-04-30 | Buy |
| TCI Chemical | B4458 | 6-Bromobenzimidazole >98.0%(T) | 4887-88-1 | 5g | $142 | 2026-04-30 | Buy |
| Apolloscientific | OR70114 | 5-Bromo-1H-benzimidazole >98% | 4887-88-1 | 5g | $21 | 2026-06-04 | Buy |
5-Bromo-1H-benzimidazole Chemical Properties, Uses, Production
Chemical Properties
off-white powder
Uses
5-Bromo-1H-benzimidazole is a key intermediate in the synthesis of various organic compounds, especially in the fields of medicine and chemical research.
Synthesis
1575-37-7
149-73-5
4887-88-1
Step 87a: Synthesis of tert-butyl 5-bromo-1H-benzo[d]imidazole-1-carboxylate (compound 0601-187) To a solution of 4-bromo-1,2-benzenediamine (3 g, 16 mmol) in N,N-dimethylformamide (DMF, 22 mL) was added trimethyl orthoformate (44 mL), which was subsequently concentrated. Concentrated hydrochloric acid (1.5 mL) was added and the reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, the mixture was diluted with deionized water (200 mL) and the pH was adjusted to 7 with saturated aqueous sodium bicarbonate. the reaction mixture was extracted with ethyl acetate (200 mL) and the organic layer was dried with anhydrous sodium sulfate and concentrated under reduced pressure to give 5-bromo-1H-benzo[d]imidazole (3.25 g, 100%) as an off-white solid. lc-MS (mass spectrum): m/z 197 [M + H]+. 1H NMR (400 MHz, DMSO-d6) δ 7.33 (t, J = 8.8 Hz, 1H), 7.55 (dd, J1 = 7.6 Hz, J2 = 40 Hz, 1H), 7.79 (d, J = 47.2 Hz, 1H), 8.26 (s, 1H), 12.61 (d, J = 25.6 Hz, 1H ).
References
[1] Patent: WO2011/130628, 2011, A1. Location in patent: Page/Page column 228
[2] Patent: US2013/102595, 2013, A1. Location in patent: Paragraph 0580; 0581
[3] Patent: JP2015/187145, 2015, A. Location in patent: Paragraph 0493
[4] Patent: US2009/326029, 2009, A1. Location in patent: Page/Page column 33
5-Bromo-1H-benzimidazole Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CHANGZHOU MALONG CHEMICALS CO., LTD. | 18651958646 | info@malongchem.com | China | 185 | 58 |
| Changzhou Xinkai Chemical Co., Ltd. | 15051102731 | 2455461715@qq.com | China | 31 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 18918157536; | sales8178@energy-chemical.com | China | 45000 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11775 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9388 | 66 |
| Accela ChemBio Co.,Ltd. | 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 |
View Latest Price from 5-Bromo-1H-benzimidazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-07 | 5-Bromo-1H-benzimidazole
4887-88-1
|
$1.00-2.10 | 1KG | 99% | 20000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-07-06 | 5-Bromo-1H-benzimidazole
4887-88-1
|
$8.00 | 1kg | 99% | 10MT | Career Henan Chemical Co |
-
- 5-Bromo-1H-benzimidazole
4887-88-1
- $1.00-2.10
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 5-Bromo-1H-benzimidazole
4887-88-1
- $8.00
- 99%
- Career Henan Chemical Co
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