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Wogonin

CAS No.
632-85-9
Chemical Name:
Wogonin
Synonyms
5,7-dihydroxy-8-methoxy-2-phenyl-4h-1-benzopyran-4-on;5,7-DIHYDROXY-8-METHOXYFLAVON;5,7-DIHYDROXY-8-METHOXYFLAVONE;5,7-dihydroxy-8-methoxy-2-phenyl-4h-1-benzopyran-4-one;WOGONIN;vogonin;WOOGONIN;WILDYAMP.E;WOGONIN(RG);WOGONIN hplc
CBNumber:
CB6408918
Molecular Formula:
C16H12O5
Molecular Weight:
284.26
MDL Number:
MFCD00017736
MOL File:
632-85-9.mol
MSDS File:
SDS
Last updated:2024-04-07 18:44:46

Wogonin Properties

Melting point 203-206°C
Boiling point 518.8±50.0 °C(Predicted)
Density 1.420±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility DMSO: ≥20mg/mL
pka 6.83±0.40(Predicted)
form Yellow solid
color Light Yellow to Yellow
λmax 319nm(EtOH)(lit.)
InChIKey XLTFNNCXVBYBSX-UHFFFAOYSA-N
LogP 2.140 (est)
CAS DataBase Reference 632-85-9(CAS DataBase Reference)
FDA UNII POK93PO28W

SAFETY

Risk and Safety Statements

Safety Statements  24/25
WGK Germany  3
RTECS  LK8331000
HS Code  29329990
NFPA 704
0
1 0

Wogonin price More Price(49)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W0769 Wogonin hydrate ≥98% (HPLC), solid 632-85-9 5mg $220 2024-03-01 Buy
Sigma-Aldrich 681670 Wogonin hydrate 632-85-9 10mg $273 2023-01-07 Buy
TCI Chemical W0010 Wogonin >98.0%(HPLC) 632-85-9 50mg $140 2024-03-01 Buy
TCI Chemical W0010 Wogonin >98.0%(HPLC) 632-85-9 250mg $418 2024-03-01 Buy
Cayman Chemical 14248 Wogonin ≥98% 632-85-9 5mg $64 2024-03-01 Buy
Product number Packaging Price Buy
W0769 5mg $220 Buy
681670 10mg $273 Buy
W0010 50mg $140 Buy
W0010 250mg $418 Buy
14248 5mg $64 Buy

Wogonin Chemical Properties,Uses,Production

Uses

Wogonin acts as an anti-inflammatory agent, attenuating ovalbumin antigen-influenced neutrophillic airway inflammation. In addition, it reverses multi-drug resistance of human myelogenous leukemia.

Definition

ChEBI: A dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-8.

General Description

Wogonin is a flavonoid component of Scutellaria baicalensis Georgi roots.

Biochem/physiol Actions

Wogonin is an anti-inflammatory agent and COX-2 inhibitor, which inhibits the induction of both iNOS and COX-2. Wogonin inhibits COX-2 (IC50 = 46 μM) without affecting COX-1. Wogonin inhibits iNOS induction and thus inhibts activation-induced C6 glial cell death. Specifically, Wogonin inhibits NF-kappaB-mediated iNOS induction.

storage

Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). 

4431-41-8
632-85-9
Synthesis of Wogonin from 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-8-methoxy-2-phenyl-, (2S)-
Global( 326)Suppliers
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View Lastest Price from Wogonin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Wogonin pictures 2024-04-26 Wogonin
632-85-9
US $0.00-0.00 / kg 0.10000000149011612kg ≥98% 20tons Chongqing Zhihe Biopharmaceutical Co., Ltd.
Wogonin pictures 2024-04-22 Wogonin
632-85-9
US $0.00 / kg 1kg 99.8% 1000 kg BINBO BIOLOGICAL CO.,LTD
Scutellaria baicalensis extract pictures 2024-04-12 Scutellaria baicalensis extract
632-85-9
US $0.00-0.00 / KG 1KG 98%,90%,40%,10% 10000kg/Month Shaanxi Haibo Biotechnology Co., Ltd
  • Wogonin pictures
  • Wogonin
    632-85-9
  • US $0.00-0.00 / kg
  • ≥98%
  • Chongqing Zhihe Biopharmaceutical Co., Ltd.
  • Wogonin pictures
  • Wogonin
    632-85-9
  • US $0.00 / kg
  • 99.8%
  • BINBO BIOLOGICAL CO.,LTD
vogonin WOGONIN WOGONIN 98.0% BY HPLC WOOGONIN WOGONIN hplc WILDYAMP.E 4H-1-Benzopyran-4-one,5,7-dihydroxy-8-methoxy-2-phenyl- 2-Phenyl-5,7-dihydroxy-8-methoxy-4H-1-benzopyran-4-one WOGONIN(RG) Wogonin ,>=98% Wogonin hydrate Wogonin, S. baicalensis Wogonin, 98%, from Scutellaria baicalensis Georgi Wogonin,HPLC≥98% Wogonin USP/EP/BP Wogonin 632-85-9 Wogonin, S. baicalensis - CAS 632-85-9 - Calbiochem 5,7-dihydroxy-8-methoxy-2-phenyl-4h-1-benzopyran-4-on 5,7-dihydroxy-8-methoxy-2-phenyl-4h-1-benzopyran-4-one 5,7-DIHYDROXY-8-METHOXYFLAVON 5,7-DIHYDROXY-8-METHOXYFLAVONE 5,7-Dihydroxy-8-methoxy-2-phenyl-4H-chromen-4-one 632-85-9 C16H12O5xH2O Caspases/Apoptosis Tri-substituted Flavones chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Inhibitors