OPIPRAMOL
- CAS No.
- 315-72-0
- Chemical Name:
- OPIPRAMOL
- Synonyms
- G-33040;Nisidana;GR-33040;Opramidol;OPIPRAMOL;NSC 169867;Opipramol in acetonitrile;N-[3-[4-(2-hydroxyethyl)piperazino]propyl]iminostilbene;4-(3-(DIBENZ(B,F)AZEPIN-5-YL)PROPYL)-1-PIPERAZINEETHANOL;1-Piperazineethanol, 4-3-(5H-dibenzb,fazepin-5-yl)propyl-
- CBNumber:
- CB6415167
- Molecular Formula:
- C23H29N3O
- Molecular Weight:
- 363.5
- MDL Number:
- MFCD00865455
- MOL File:
- 315-72-0.mol
- MSDS File:
- SDS
| Melting point | 100-1010C |
|---|---|
| Boiling point | 494.88°C (rough estimate) |
| Density | 1.0920 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | -20°C Freezer |
| solubility | Acetonitrile: slightly soluble; Chloroform: slightly soluble; Methanol: slightly soluble |
| pka | pKa 8(H2O,t =25,I=0.01(NaCl)) (Uncertain) |
| form | Solid |
| color | Light yellow to yellow |
| BRN | 627076 |
| Major Application |
forensics and toxicology veterinary |
| InChI | 1S/C23H29N3O/c27-19-18-25-16-14-24(15-17-25)12-5-13-26-22-8-3-1-6-20(22)10-11-21-7-2-4-9-23(21)26/h1-4,6-11,27H,5,12-19H2 |
| InChIKey | YNZFUWZUGRBMHL-UHFFFAOYSA-N |
| SMILES | OCCN(CC1)CCN1CCCN2C(C=CC=C3)=C3C=CC4=C2C=CC=C4 |
| FDA UNII | D23ZXO613C |
| ATC code | N06AA05 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H410 | |||||||||
| Precautionary statements | P273-P501 | |||||||||
| Hazard Codes | Xn,N | |||||||||
| Risk Statements | 22-50/53 | |||||||||
| Safety Statements | 60-61 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | TL8750000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
OPIPRAMOL price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29471 | Opipramol ≥98% | 315-72-0 | 5mg | $43 | 2026-04-30 | Buy |
| Cayman Chemical | 29471 | Opipramol ≥98% | 315-72-0 | 10mg | $77 | 2026-04-30 | Buy |
| Cayman Chemical | 29471 | Opipramol ≥98% | 315-72-0 | 25mg | $168 | 2026-04-30 | Buy |
| TRC | TRC-O669600-5MG | Opipramol >95%(HPLC) | 315-72-0 | 5mg | $167 | 2026-06-03 | Buy |
| TRC | TRC-O669600-25MG | Opipramol >95%(HPLC) | 315-72-0 | 25mg | $553 | 2026-06-03 | Buy |
OPIPRAMOL Chemical Properties, Uses, Production
Chemical Properties
Crystalline Solid
Originator
Insidon,Geigy,W. Germany,1962
Uses
Antidepressant; antipsychotic
Definition
ChEBI: 2-[4-[3-(11-benzo[b][1]benzazepinyl)propyl]-1-piperazinyl]ethanol is a dibenzoazepine.
Manufacturing Process
A solution of 5-(3-toluene-p-sulfonyloxypropyl)dibenzazepine (9.2g) and 1-(2hydroxyethyl)piperazine (8.6g) in anhydrous toluene (50 cc) is heated at boiling point under reflux for 4 hours.
After cooling, distilled water (75 cc) is added. The aqueous phase is decanted. The toluene solution is washed with distilled water (25 cc) and then extracted with N hydrohloric acid (40 cc). The hydrochloric acid solution is made alkaline to phenolphthalein with sodium hydroxide (d = 1.33).The base which separates is extracted with chloroform (50 cc). The chloroform solution is dried over anhydrous sodium sulfate and then evaporated to dryness. There are obtained 5-[3-(4-β-hydroxyethylpiperazino)propyl]dibenzazepine (7.95g), the dihydrochloride of which, crystallized from ethanol, melts at about 210°C.
Therapeutic Function
Antidepressant, Antipsychotic
OPIPRAMOL Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 18916372613 | yanzihan@shyuanye.com | China | 87240 | 60 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684; | sales@rrkchem.com | China | 57330 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
