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ChemicalBook >> CAS DataBase List >>2-Chloro-N-MethylethanaMine Hydrochloride

2-Chloro-N-MethylethanaMine Hydrochloride

2-Chloro-N-MethylethanaMine Hydrochloride Structure
2-Chloro-N-MethylethanaMine Hydrochloride structure
CAS No.
4535-90-4
Chemical Name:
2-Chloro-N-MethylethanaMine Hydrochloride
Synonyms
2-MethylaMinoethyl chloride HCl;(2-Chloroethyl)-methylamine HCl;2-Chloro-N-MethylethanaMine HCl;2-Chloroethyl-Methyl-Azanium Chloride;2-Chloro-N-MethylethanaMiniuM chloride;2-chloroethyl(methyl)ammonium chloride;2-chloro-n-methyl-ethylaminhydrochloride;2-chloro-n-methyl-ethanaminhydrochloride;N-Methyl-2-chloroethylaMine Hydrochloride;2-Chloro-N-MethylethylaMine Hydrochloride
CBNumber:
CB6506054
Molecular Formula:
C3H9Cl2N
Molecular Weight:
130.01626
MDL Number:
MFCD00050517
MOL File:
4535-90-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:31
Product description Number Pack Size Price
2-Chloro-N-methylethanamineHydrochloride C428323 50mg $60
2-MethylaminoethylchlorideHCl V6020 25g $67
2-MethylaminoethylchlorideHCl V6020 1g $14
2-MethylaminoethylchlorideHCl V6020 5g $21
2-METHYLAMINOETHYL CHLORIDE HYDROCHLORIDE 95.00% CHM0309985 5MG $503.29
More product size
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2-Chloro-N-MethylethanaMine Hydrochloride Properties

Melting point 89 °C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form solid
color White to off-white
InChI InChI=1S/C3H8ClN.ClH/c1-5-3-2-4;/h5H,2-3H2,1H3;1H
InChIKey FGSHJLJPYBUBHO-UHFFFAOYSA-N
SMILES C(NC)CCl.Cl
EPA Substance Registry System Ethanamine, 2-chloro-N-methyl-, hydrochloride (4535-90-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P305+P351+P338
TSCA  TSCA listed
HS Code  2921199990

2-Chloro-N-MethylethanaMine Hydrochloride price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C428323 2-Chloro-N-methylethanamineHydrochloride 4535-90-4 50mg $60 2021-12-16 Buy
AK Scientific V6020 2-MethylaminoethylchlorideHCl 4535-90-4 25g $67 2021-12-16 Buy
AK Scientific V6020 2-MethylaminoethylchlorideHCl 4535-90-4 1g $14 2021-12-16 Buy
AK Scientific V6020 2-MethylaminoethylchlorideHCl 4535-90-4 5g $21 2021-12-16 Buy
American Custom Chemicals Corporation CHM0309985 2-METHYLAMINOETHYL CHLORIDE HYDROCHLORIDE 95.00% 4535-90-4 5MG $503.29 2021-12-16 Buy
Product number Packaging Price Buy
C428323 50mg $60 Buy
V6020 25g $67 Buy
V6020 1g $14 Buy
V6020 5g $21 Buy
CHM0309985 5MG $503.29 Buy

2-Chloro-N-MethylethanaMine Hydrochloride Chemical Properties,Uses,Production

Uses

2-Chloro-N-methylethanamine Hydrochloride is used in the preparation of pyrimidine derivatives and related heterocycles as CDK inhibitors for treatment of diseases.

Uses

2-Chloro-N-Methylethanamine Hydrochloride is an aminoalkoxyimino derivative used in the preparation of amino derivatives of B-homoandrostanes and B-heteroandrostanes for the treatment of cardiovascular disorders.

Synthesis

2-Methylaminoethanol

109-83-1

2-Chloro-N-MethylethanaMine Hydrochloride

4535-90-4

Example 2: General procedure for the synthesis of 2-chloro-N-methylethylamine hydrochloride from N-methyl-2-hydroxyethylamine 1. Dry hydrogen chloride gas was passed into a solution of dichloromethane (25 ml) containing 2-(methylamino)ethanol (10 g, 133 mmol) under stirring conditions until the mixture turned wet litmus paper red. 2. The reaction mixture was cooled to 0 °C and thionyl chloride (15.82 g, 133 mmol) was added slowly and dropwise. 3. After the dropwise addition was completed, the reaction mixture was stirred at room temperature overnight. 4. After completion of the reaction, the solvent was removed by distillation under reduced pressure to afford the target product 2-chloro-N-methylethylamine hydrochloride as a white solid (16.60 g, 96% yield). Product characterization: melting point 95°-100°C; 1H NMR (DMSO-d6) δ 4.00 (t, 2H, J = 6.28Hz), 3.36 (t, 2H, J = 6.29Hz), 2.81 (s, 3H); IR (KBr) ν 3400, 2960, 2750, 2420, 1730, 1580, 1460, 1390, 1310, 1270, 1200, 1310, 1270, 1200, 1390, 1390. 1310, 1270, 1200, 1150, 1165, 1005, 990, 900, 860, 710 cm-1.

References

[1] Journal of Medicinal Chemistry, 1995, vol. 38, # 14, p. 2672 - 2680
[2] Patent: US5233031, 1993, A
[3] Chemical and Pharmaceutical Bulletin, 2002, vol. 50, # 7, p. 941 - 959
[4] Journal of the Chemical Society. Dalton Transactions, 2001, # 8, p. 1306 - 1318
[5] Journal of medicinal chemistry, 1992, vol. 35, # 17, p. 3246 - 3253

2-Chloro-N-MethylethanaMine Hydrochloride Preparation Products And Raw materials

Raw materials

2-Methylaminoethanol 2-methylaminoethanol hydrochloride Dichloromethane Thionyl chloride

Preparation Products

1-Methylpiperazin-2-one

2-Chloro-N-MethylethanaMine Hydrochloride Suppliers

Global( 107)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81139210 +86-18192627656 1059@dideu.com China 3590 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29640 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29819 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Finetech Industry Limited 		+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9540 58
Labnetwork lnc. 		+86-27-50766799 +8618062016861 contact@labnetwork.com China 19987 58
Hebei Fengjia New Material Co., Ltd 		+86-0311-87836622 +86-18712993135 sales01@tairunfaz.com China 8051 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 24597 58
GIHI CHEMICALS CO.,LIMITED 		+86-571-86217390; +8618058761490 info@gihichemicals.com China 49968 58
Supplier Advantage
Shaanxi Dideu Medichem Co. Ltd 		58
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
career henan chemical co 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Finetech Industry Limited 		58
Labnetwork lnc. 		58
Hebei Fengjia New Material Co., Ltd 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
GIHI CHEMICALS CO.,LIMITED 		58

View Lastest Price from 2-Chloro-N-MethylethanaMine Hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-N-MethylethanaMine Hydrochloride pictures 2025-12-12 2-Chloro-N-MethylethanaMine Hydrochloride
4535-90-4
 US $25.00-11.00 / KG 1KG 99% 200000KG Shaanxi Dideu Medichem Co. Ltd
2-Chloro-N-MethylethanaMine Hydrochloride pictures 2025-12-01 2-Chloro-N-MethylethanaMine Hydrochloride
4535-90-4
 US $0.00-0.00 / KG 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
2-Chloro-N-MethylethanaMine Hydrochloride pictures 2025-09-25 2-Chloro-N-MethylethanaMine Hydrochloride
4535-90-4
 US $5.00-2.00 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd

2-Chloro-N-MethylethanaMine Hydrochloride Spectrum

2-Chloro-N-MethylethanaMine Hydrochloride(4535-90-4)1HNMR

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2-chloro-n-methyl-ethanaminhydrochloride 2-chloro-n-methyl-ethylaminhydrochloride 2-chloroethyl(methyl)ammonium chloride 2-Chloro-N-MethylethylaMine Hydrochloride N-Methyl-2-chloroethylaMine Hydrochloride 2-Chloro-N-MethylethanaMine HCl (2-chloroethyl)(Methyl)aMine hydrochloride 2-MethylaMinoethyl chloride HCl 2-Chloro-N-MethylethanaMiniuM chloride EthanaMine,2-chloro-N-Methyl-, hydrochloride (1:1) 2-Chloroethyl-Methyl-Azanium Chloride 2-Methylaminoethyl Chloride Hydrochloride 2-Chloroethyl-Methyl-Ammonium Chloride 2-N-Methylaminoethyl chloride hydrohloride (2-Chloroethyl)-methylamine HCl N-Methyl-β-chloroethylamine hydrochloride 4535-90-4 CH3NHCH2CH2ClHCl Amines, Intermediates