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2-Dimethylaminoisopropyl chloride hydrochloride

2-Dimethylaminoisopropyl chloride hydrochloride
2-Dimethylaminoisopropyl chloride hydrochloride structure
Chemical Name:
2-Dimethylaminoisopropyl chloride hydrochloride
DMIC;2-DMPC;DMIC 99%min;4584-49-0, Fandachem;2-Dimethylaminoisopropyl;intermediate of Methadone;cas no. 4584-49-0 Fandachem;N-(2-CHLORO-PROPYL)DIMETHYLAMINE;2-CHLORO-1-(DIMETHYLAMINO)PROPANEHCL;2-CHLORO-N,N-DIMETHYLPROPYLAMINE HCL
Molecular Formula:
Formula Weight:
MOL File:

2-Dimethylaminoisopropyl chloride hydrochloride Properties

Melting point:
187-190 °C(lit.)
storage temp. 
Store below +30°C.
Crystalline Powder
White to light cream
5-6 (500g/l, H2O, 20℃)
Water Solubility 
2000 g/L (20 º C)
CAS DataBase Reference
4584-49-0(CAS DataBase Reference)
EPA Substance Registry System
2-Chloro-N,N-dimethyl-1-propanamine hydrochloride (4584-49-0)
  • Risk and Safety Statements
Signal word  Warning
Hazard statements  H301-H302-H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338-P280a-P301+P310a-P405-P501a
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36
RIDADR  2811
WGK Germany  3
RTECS  TY1225000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29211980

2-Dimethylaminoisopropyl chloride hydrochloride price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D142409 2-Chloro-N,N-dimethylpropylamine hydrochloride 98% 4584-49-0 100g $28 2021-12-16 Buy
TCI Chemical D1665 2-Chloro-1-(dimethylamino)propane Hydrochloride >98.0%(T) 4584-49-0 25g $22 2021-12-16 Buy
TCI Chemical D1665 2-Chloro-1-(dimethylamino)propane Hydrochloride >98.0%(T) 4584-49-0 500g $200 2021-12-16 Buy
Alfa Aesar B20882 2-Dimethylaminoisopropyl chloride hydrochloride, 98% 4584-49-0 500g $82.8 2021-12-16 Buy
Alfa Aesar B20882 2-Dimethylaminoisopropyl chloride hydrochloride, 98% 4584-49-0 100g $25.4 2021-12-16 Buy

2-Dimethylaminoisopropyl chloride hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Colourless to pale beige crystalline powder


Hydrochloride salt of 2-Dimethylaminoisopropyl Chloride, used in the synthesis of analogues of lipophilic chalcones, which act as antitubercular agents.


2-Chloro-N,N-dimethylpropylamine hydrochloride (DMIC) is used as intermediate for the syntheses of pharmaceuticals (e.g. isothipendyl, methadone and promethazine) 

General Description

Off-white chunky solid.

Air & Water Reactions

2-Dimethylaminoisopropyl chloride hydrochloride is hygroscopic. Soluble in water.

Reactivity Profile

2-Dimethylaminoisopropyl chloride hydrochloride is incompatible with strong oxidizing agents. . Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Fire Hazard

Flash point data for 2-Dimethylaminoisopropyl chloride hydrochloride are not available; however, 2-Dimethylaminoisopropyl chloride hydrochloride is probably combustible.

Chemical Synthesis

Following the procedure of Schultz and Sprague, J. Am. Chem. Soc., 70, 48 (1948), a solution containing 3.77 g. of 1-dimethylamino-2-propanol and 10 ml. of chloroform was cooled with stirring to a temperature of about 0° C. A solution of 5.72 g. of freshly distilled thionylchloride in 2 ml. of chloroform was added thereto. The reaction mixture was allowed to come to ambient temperature over a period of about 30 minutes and was then heated to refluxing temperature for an additional 30 minutes. The precipitated material redissolved on heating. 1-Dimethylamino-2-chloropropane hydrochloride began to crystallize from the boiling solvent. The reaction mixture was cooled, diluted with ether and filtered. The reaction product comprising 1-dimethylamino-2-chloropropane hydrochloride weighed about 5.5 g. (95 percent yield). Recrystallization yielded purified 1-dimethylamino-2-chloropropane hydrochloride melting at 192°-194° C.

2-Dimethylaminoisopropyl chloride hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

2-Dimethylaminoisopropyl chloride hydrochloride Suppliers

Global( 243)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Jinan Qinmu Fine Chemical Co.,Ltd.
18660799346 18363098612
+86 531 8316 6650 CHINA 1009 58
Hebei Minshang Biotechnology Co.,Ltd
+8613582176207 China 302 58
career henan chemical co
+86-0371-55982848 China 29953 58
Univar Solutions(China) Co., Ltd.
86-21-61932700 CHINA 295 58
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13315122300 86-311-80292533 CHINA 309 58
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Xi'an ZB Biotech Co.,Ltd
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0086-133 3137 7233 CHINA 289 58
Shanxi Lianxu New Material Co., LTD
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Shanghai CRM New Material Technology Co., LTD
Whatsapp:+8613020139835 Wickr me:lucyzxy China 299 58

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View Lastest Price from 2-Dimethylaminoisopropyl chloride hydrochloride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2022-01-25 2-Dimethylaminoisopropyl chloride hydrochloride
US $0.00 / Kg/Drum 1KG 99% 100mt Jinan Finer Chemical Co., Ltd
2022-01-25 2-Dimethylaminoisopropyl chloride hydrochloride
US $9.50 / KG 1KG 99% 1000tons Hong Kong Tiansheng New Material Trading Co., Ltd
2022-01-24 2-Dimethylaminoisopropyl chloride hydrochloride
US $45.00-55.00 / KG 0.5KG >99% 20tons Anhui Rencheng Technology Co., Ltd

2-Dimethylaminoisopropyl chloride hydrochloride Spectrum

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