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2-Dimethylaminoisopropyl chloride hydrochloride

2-Dimethylaminoisopropyl chloride hydrochloride
2-Dimethylaminoisopropyl chloride hydrochloride structure
CAS No.
4584-49-0
Chemical Name:
2-Dimethylaminoisopropyl chloride hydrochloride
Synonyms
DMIC;2-DMPC;DMIC 99%min;4584-49-0, Fandachem;2-Dimethylaminoisopropyl;intermediate of Methadone;cas no. 4584-49-0 Fandachem;N-(2-CHLORO-PROPYL)DIMETHYLAMINE;2-CHLORO-1-(DIMETHYLAMINO)PROPANEHCL;2-CHLORO-N,N-DIMETHYLPROPYLAMINE HCL
CBNumber:
CB3235881
Molecular Formula:
C5H13Cl2N
Formula Weight:
158.07
MOL File:
4584-49-0.mol

2-Dimethylaminoisopropyl chloride hydrochloride Properties

Melting point:
187-190 °C(lit.)
storage temp. 
Store below +30°C.
solubility 
2000g/l
form 
Crystalline Powder
color 
White to light cream
PH
5-6 (500g/l, H2O, 20℃)
Water Solubility 
2000 g/L (20 º C)
Sensitive 
Hygroscopic
BRN 
3670215
InChIKey
OCWGRWAYARCRTQ-UHFFFAOYSA-N
CAS DataBase Reference
4584-49-0(CAS DataBase Reference)
FDA UNII
AO9WB15SNZ
EPA Substance Registry System
2-Chloro-N,N-dimethyl-1-propanamine hydrochloride (4584-49-0)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07,GHS06
Signal word  Warning
Hazard statements  H301-H302-H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338-P280a-P301+P310a-P405-P501a
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36
RIDADR  2811
WGK Germany  3
RTECS  TY1225000
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  29211980

2-Dimethylaminoisopropyl chloride hydrochloride price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D142409 2-Chloro-N,N-dimethylpropylamine hydrochloride 98% 4584-49-0 100g $28 2021-12-16 Buy
TCI Chemical D1665 2-Chloro-1-(dimethylamino)propane Hydrochloride >98.0%(T) 4584-49-0 25g $22 2021-12-16 Buy
TCI Chemical D1665 2-Chloro-1-(dimethylamino)propane Hydrochloride >98.0%(T) 4584-49-0 500g $200 2021-12-16 Buy
Alfa Aesar B20882 2-Dimethylaminoisopropyl chloride hydrochloride, 98% 4584-49-0 500g $82.8 2021-12-16 Buy
Alfa Aesar B20882 2-Dimethylaminoisopropyl chloride hydrochloride, 98% 4584-49-0 100g $25.4 2021-12-16 Buy

2-Dimethylaminoisopropyl chloride hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Colourless to pale beige crystalline powder

Uses

Hydrochloride salt of 2-Dimethylaminoisopropyl Chloride, used in the synthesis of analogues of lipophilic chalcones, which act as antitubercular agents.

Uses

2-Chloro-N,N-dimethylpropylamine hydrochloride (DMIC) is used as intermediate for the syntheses of pharmaceuticals (e.g. isothipendyl, methadone and promethazine) 

General Description

Off-white chunky solid.

Air & Water Reactions

2-Dimethylaminoisopropyl chloride hydrochloride is hygroscopic. Soluble in water.

Reactivity Profile

2-Dimethylaminoisopropyl chloride hydrochloride is incompatible with strong oxidizing agents. . Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Fire Hazard

Flash point data for 2-Dimethylaminoisopropyl chloride hydrochloride are not available; however, 2-Dimethylaminoisopropyl chloride hydrochloride is probably combustible.

Chemical Synthesis


Following the procedure of Schultz and Sprague, J. Am. Chem. Soc., 70, 48 (1948), a solution containing 3.77 g. of 1-dimethylamino-2-propanol and 10 ml. of chloroform was cooled with stirring to a temperature of about 0° C. A solution of 5.72 g. of freshly distilled thionylchloride in 2 ml. of chloroform was added thereto. The reaction mixture was allowed to come to ambient temperature over a period of about 30 minutes and was then heated to refluxing temperature for an additional 30 minutes. The precipitated material redissolved on heating. 1-Dimethylamino-2-chloropropane hydrochloride began to crystallize from the boiling solvent. The reaction mixture was cooled, diluted with ether and filtered. The reaction product comprising 1-dimethylamino-2-chloropropane hydrochloride weighed about 5.5 g. (95 percent yield). Recrystallization yielded purified 1-dimethylamino-2-chloropropane hydrochloride melting at 192°-194° C.

2-Dimethylaminoisopropyl chloride hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products


2-Dimethylaminoisopropyl chloride hydrochloride Suppliers

Global( 243)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Jinan Qinmu Fine Chemical Co.,Ltd.
18660799346 18363098612
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+8613582176207
cathy@hbminshang.cn China 302 58
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29953 58
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15902132654
86-21-61932700 Ivy.zhuang@univarsolutions.com CHINA 295 58
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0086-133 3137 7233
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+8618903404542
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View Lastest Price from 2-Dimethylaminoisopropyl chloride hydrochloride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2022-01-25 2-Dimethylaminoisopropyl chloride hydrochloride
4584-49-0
US $0.00 / Kg/Drum 1KG 99% 100mt Jinan Finer Chemical Co., Ltd
2022-01-25 2-Dimethylaminoisopropyl chloride hydrochloride
4584-49-0
US $9.50 / KG 1KG 99% 1000tons Hong Kong Tiansheng New Material Trading Co., Ltd
2022-01-24 2-Dimethylaminoisopropyl chloride hydrochloride
4584-49-0
US $45.00-55.00 / KG 0.5KG >99% 20tons Anhui Rencheng Technology Co., Ltd

2-Dimethylaminoisopropyl chloride hydrochloride Spectrum


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