8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE
- CAS No.
- 51116-01-9
- Chemical Name:
- 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE
- Synonyms
- BR-CGMP, NA;8-BR-CGMP NA;8-BROMO-CGMP NA;Einecs 256-993-8;8-BROMO-CGMP SODIUM;8-BR-CGMP SODIUM SALT;(115974-70-4) 8-AET-cGMP;8-BROMO-CGMP, SODIUM SALT;8-bromo-Cyclic GMP (sodium salt);8 Bromo cGMP sodium,8BromocGMP sodium
- CBNumber:
- CB6687726
- Molecular Formula:
- C10H12BrN5NaO7P
- Molecular Weight:
- 448.1
- MDL Number:
- MFCD03703483
- MOL File:
- 51116-01-9.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
WGK Germany | 3 |
---|---|
F | 10-21 |
HS Code | 29349990 |
8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE price More Price(18)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | B1381 | 8-Bromoguanosine 3′,5′-cyclic monophosphate sodium salt ≥98% (HPLC), powder | 51116-01-9 | 10mg | $89.4 | 2024-03-01 | Buy |
Sigma-Aldrich | 203820 | Guanosine 3?,5?-cyclic Monophosphate, 8-Bromo-, Sodium Salt | 51116-01-9 | 25mg | $166 | 2024-03-01 | Buy |
Cayman Chemical | 15992 | 8-bromo-Cyclic GMP (sodium salt) ≥98% | 51116-01-9 | 5mg | $44 | 2024-03-01 | Buy |
Cayman Chemical | 15992 | 8-bromo-Cyclic GMP (sodium salt) ≥98% | 51116-01-9 | 10mg | $74 | 2024-03-01 | Buy |
Sigma-Aldrich | B1381 | 8-Bromoguanosine 3′,5′-cyclic monophosphate sodium salt ≥98% (HPLC), powder | 51116-01-9 | 25mg | $179 | 2024-03-01 | Buy |
8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Chemical Properties,Uses,Production
Description
8-bromo-Cyclic GMP (8-bromo-cGMP) is a cell-permeable analog of cGMP that exhibits greater resistance to hydrolysis by phosphodiesterases than its parent compound. It preferentially activates cGMP-dependent protein kinase. At 1 μM-0.1 mM, 8-bromo-cGMP can inhibit acetylcholine-induced increases in intracellular calcium concentrations.
Chemical Properties
White powder
Uses
8-bromo-cGMP activates cGMP-dependent protein kinase. It can also inhibit acetylcholine-induced increases in intracellular calcium concentrations.
Definition
ChEBI: Sodium 8-bromo-3',5'-cyclic GMP is an organic sodium salt having 8-bromoguanosine 3',5'-cyclic phosphate as the counterion. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro. It has a role as a protein kinase G agonist and a muscle relaxant. It contains an 8-bromo-3',5'-cyclic GMP(1-).
Biological Activity
Membrane permeable cGMP analog that activates protein kinase G (PKG). 4.3-fold more potent than cGMP in activating PKG1 α and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro .
storage
Desiccate at -20°C
8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Preparation Products And Raw materials
Raw materials
Preparation Products
8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 9980 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9708 | 58 |
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