1-Pentyl-3-(1-naphthoyl)indole
- CAS No.
- 209414-07-3
- Chemical Name:
- 1-Pentyl-3-(1-naphthoyl)indole
- Synonyms
- JWH-18;AM-678;JWH -018;jwh-018 powder;JWH-018 (AM678);jwh-018 supplier;JWH 018 (solution);JWH-018 (Spice Cannabinoid);JWH 018 (exempt preparation);1-Pentyl-3-(1-naphthoyl)indole
- CBNumber:
- CB6947761
- Molecular Formula:
- C24H23NO
- Molecular Weight:
- 341.45
- MDL Number:
- MFCD11846245
- MOL File:
- 209414-07-3.mol
| Melting point | 55-59°C |
|---|---|
| Boiling point | 534.2±23.0 °C(Predicted) |
| Density | 1.09±0.1 g/cm3(Predicted) |
| Flash point | 9℃ |
| storage temp. | Desiccate at -20°C |
| solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; Methanol: 30 mg/ml |
| form | A neat solid |
| FDA UNII | G391998J57 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H301+H311+H331-H370 | |||||||||
| Precautionary statements | P210-P260-P280-P301+P310-P311 | |||||||||
| Hazard Codes | F,T | |||||||||
| Risk Statements | 11-23/24/25-39/23/24/25-25 | |||||||||
| Safety Statements | 7-16-36/37-45 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| WGK Germany | 1 | |||||||||
| DEA Controlled Substances | CSCN: 7118 CSA SCH: Schedule I NARC: No |
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| NFPA 704 |
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1-Pentyl-3-(1-naphthoyl)indole Chemical Properties,Uses,Production
Description
JWH 018 (CRM) (Item No. 27973) is a certified reference material categorized as a synthetic cannabinoid. It has been found in Spice/K2-type herbal blends and may have neurotoxic properties. JWH 018 is regulated as a Schedule I compound in the United States. JWH 018 (CRM) (Item No. 27973) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.
Chemical Properties
White Powder
Uses
Analgesic Drug
Uses
JWH 018 is the 18th compound synthesized in a series of more than 470 analogs and metabolites of ?9-Tetrahydro- cannabinol (THC) (T293200), the active component of marijuana. JWH 018 acts as cannabinoid receptor. Controlled substance.
Definition
ChEBI: JWH 018 is an indolecarboxamide.
Biological Activity
Potent cannabinoid receptor agonist with mild selectivity for CB 2 (K i values are 2.94 and 9.0 nM for CB 2 and CB 1 receptors respectively).