MEN 935
- CAS No.
- 75708-29-1
- Chemical Name:
- MEN 935
- Synonyms
- MEN 935;3-[3-[(2-hydroxy-3-naphthalen-1-yloxypropyl)amino]-3-methylbutyl]-1H-benzimidazol-2-one
- CBNumber:
- CB71326382
- Molecular Formula:
- C25H29N3O3.ClH.H2O
- Molecular Weight:
- 473.998
- MDL Number:
- MFCD01658791
- MOL File:
- 75708-29-1.mol
FDA UNII | D9QT537UWA |
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MEN 935 Chemical Properties,Uses,Production
Originator
Adimolol hydrochloride ,ZYF Pharm Chemical
Uses
Adimolol is an antihypertensive agent and a β-adrenoceptor blocker.
Manufacturing Process
A mixture consisting of 3 g of 1-(3-amino-3,3-dimethyl-n-propyl)
benzimidazolidinone-2, 3.3 g of 1-[naphthyl-(1)-oxyl]propylene-(2,3)-epoxide
and 12 ml of 98% ethanol were refluxed for three hours. Thereafter, the
ethanol was distilled off, the residue was taken up in some methanol, and the
solution was acidified with 1 N hydrochloric acid and then extracted with ethyl
acetate. The ethyl acetate was distilled out of the extract solution, and ether
and some water were added to the residue, whereupon a crystalline substance
separated out. The product was recrystallized from ethanol, yielding 60% of
theory of ()-1-(3-((2-hydroxy-3-(1-naphthyloxy)propyl)amino)-3-
methylbutyl)-2-benzimidazolinone, which had a melting point of 161°C.
In practice it is usually used as hydrochloride.
Therapeutic Function
Alpa- and Beta-adrenergic blocker
MEN 935 Preparation Products And Raw materials
Raw materials
Preparation Products
MEN 935 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1249 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 16377 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
Energy Chemical | 58 |
Beijing Biocreative Technology Co., Ltd. | 58 |
TargetMol Chemicals Inc. | 58 |