Methyl 2-(3-broMophenyl)-2-Methylpropanoate
- CAS No.
- 251458-15-8
- Chemical Name:
- Methyl 2-(3-broMophenyl)-2-Methylpropanoate
- Synonyms
- 2-(3-bromophenyl) -2-methylpropionate;Methyl 2-(3-broMophenyl)-2-Methylpropanoate;Benzeneacetic acid, 3-bromo-α,α-dimethyl-, methyl ester;2-(3-Bromo-phenyl)-2-methyl-propionic acid methyl ester;3-Bromo-Alpha,Alpha-Dimethyl-Benzeneacetic Acid Methyl Ester
- CBNumber:
- CB72710171
- Molecular Formula:
- C11H13BrO2
- Molecular Weight:
- 257.12
- MDL Number:
- MFCD13192201
- MOL File:
- 251458-15-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl2-(3-bromophenyl)-2-methylpropanoate | 6909AJ | 1g | $131 |
| 2-(3-Bromo-phenyl)-2-methyl-propionicacidmethylester 95% | BB20-6659 | 1g | $150 |
| Methyl2-(3-bromophenyl)-2-methylpropanoate 95% | CM251705 | 5g | $224 |
| Methyl2-(3-bromophenyl)-2-methylpropanoate 95+% | CD12091586 | 5g | $238 |
| Methyl2-(3-bromophenyl)-2-methylpropanoate | 251458158 | 5g | $254.4 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Methyl 2-(3-broMophenyl)-2-Methylpropanoate price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | 6909AJ | Methyl2-(3-bromophenyl)-2-methylpropanoate | 251458-15-8 | 1g | $131 | 2021-12-16 | Buy |
| Chemcia Scientific | BB20-6659 | 2-(3-Bromo-phenyl)-2-methyl-propionicacidmethylester 95% | 251458-15-8 | 1g | $150 | 2021-12-16 | Buy |
| Chemenu | CM251705 | Methyl2-(3-bromophenyl)-2-methylpropanoate 95% | 251458-15-8 | 5g | $224 | 2021-12-16 | Buy |
| Crysdot | CD12091586 | Methyl2-(3-bromophenyl)-2-methylpropanoate 95+% | 251458-15-8 | 5g | $238 | 2021-12-16 | Buy |
| Alichem | 251458158 | Methyl2-(3-bromophenyl)-2-methylpropanoate | 251458-15-8 | 5g | $254.4 | 2021-12-16 | Buy |
Methyl 2-(3-broMophenyl)-2-Methylpropanoate Chemical Properties,Uses,Production
Synthesis
150529-73-0
74-88-4
251458-15-8
Sodium hydride (60% oil solution, 10.4 g, 436 mmol) was added to tetrahydrofuran (400 mL) under argon protection, stirred and heated to 50 °C. Subsequently, methyl 2-(3-bromophenyl)acetate (20 g, 87.3 mmol) was added. The reaction mixture was added dropwise over 30 minutes and continued to be heated at 50 °C for 90 minutes. After completion of the reaction, the temperature was lowered to below 40 °C and iodomethane (13 mL, 209 mmol) was added over 10 min. The resulting suspension was stirred overnight at room temperature. At the end of the reaction, water (300 mL) was carefully added and the reaction mixture was concentrated. The residue was partitioned between ether (400 mL) and water. The aqueous layer was extracted with ether (400 mL) and the combined organic layers were dried over anhydrous sodium sulfate and concentrated to give the crude product. The crude product was purified by column chromatography using a gradient elution with a heptane solution of 0 to 20% ethyl acetate to afford methyl 2-(3-bromophenyl)-2-methylpropionate (14.96 g, 58 mmol, 67% yield).1H NMR (400 MHz, CDCl3): δ 7.47 (t, 1H), 7.37 (dt, 1H), 7.24 (dt. 1H), 7.18 (t, 1H), 3.65 (s, 3H), 1.55 (s, 6H).
References
[1] Patent: US2010/197591, 2010, A1. Location in patent: Page/Page column 15-16
[2] Journal of Medicinal Chemistry, 2008, vol. 51, # 3, p. 392 - 395
[3] Patent: US2005/80111, 2005, A1
[4] Patent: WO2014/201073, 2014, A1. Location in patent: Paragraph 00218
[5] Patent: WO2004/48374, 2004, A1. Location in patent: Page 47
Methyl 2-(3-broMophenyl)-2-Methylpropanoate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Shanghai Scochem Technology Co., Ltd | +86-021-33758897 +86-13701882790 | sales@scochem.com | China | 1977 | 58 |
| Young Lively PharminBlock Co.,Ltd | +undefined18600731423 | jason_gao@yl-pharminblock.com | China | 1944 | 58 |
| ShenZhen H&D Pharmaceutical Technology Co., LTD | +8618627948422 | sale@hdimpurity.com | China | 3681 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10462 | 58 |
| Chengdu Forest Science and Technology Development Co., Ltd. | 18030648795 18030648795 | sales@cdforestchem.com | China | 1991 | 58 |
| Bide Pharmatech Ltd. | 400-400-164-7117 18317119277 | product02@bidepharm.com | China | 39999 | 60 |
| Shanghai ShiXian Chemical Technology Co., Ltd. | 13764359345 | 990877971@qq.com | China | 1735 | 50 |
View Lastest Price from Methyl 2-(3-broMophenyl)-2-Methylpropanoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-15 | Methyl 2-(3-broMophenyl)-2-Methylpropanoate
251458-15-8
|
US $1.00 / KG | 1KG | 99.0% | 100kg | Career Henan Chemical Co |
-
- Methyl 2-(3-broMophenyl)-2-Methylpropanoate
251458-15-8
- US $1.00 / KG
- 99.0%
- Career Henan Chemical Co
