ChemicalBook >> CAS DataBase List >>2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE
2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE
- CAS No.
- 186689-07-6
- Chemical Name:
- 2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE
- Synonyms
- 2-NBDG;NBD-GLUCOSE;2-NBD-Glucose;2-NBDG min. 95%;Alitretinoin Impurity 14;2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose;2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE;D-Glucose, 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-;2-NBDG,2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose;2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE (NBDG)
- CBNumber:
- CB7380499
- Molecular Formula:
- C12H14N4O8
- Molecular Weight:
- 342.26
- MDL Number:
- MFCD20527306
- MOL File:
- Mol file
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| Melting point | 137 - 140°C |
|---|---|
| Boiling point | 740.0±70.0 °C(Predicted) |
| Density | 1.750±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Soluble in DMSO (up to 10 mg/ml). |
| form | solid |
| pka | 12.96±0.20(Predicted) |
| color | Dark yellow to orange/red |
| BRN | 7603370 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. |
| FDA UNII | JE4F4P486R |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2934999090 | |||||||||
| NFPA 704 |
|
2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 72987 | 2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose ≥97% (HPLC) | 186689-07-6 | 1mg | $322 | 2024-03-01 | Buy |
| Cayman Chemical | 11046 | 2-NBDG ≥98% (mixture of α and β) | 186689-07-6 | 1mg | $39 | 2024-03-01 | Buy |
| Cayman Chemical | 11046 | 2-NBDG ≥98% (mixture of α and β) | 186689-07-6 | 5mg | $117 | 2024-03-01 | Buy |
| Cayman Chemical | 11046 | 2-NBDG ≥98% (mixture of α and β) | 186689-07-6 | 10mg | $176 | 2024-03-01 | Buy |
| Tocris | 6065 | 2-NBDG ≥97%(HPLC) | 186689-07-6 | 5 | $288 | 2021-12-16 | Buy |
2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE Chemical Properties,Uses,Production
Description
2-NBDG is a fluorescent derivative of glucose whose uptake is competitively inhibited by D-glucose , but not L-glucose or sucrose, in E. coli. It has been used to monitor glucose uptake by bacteria and live mammalian cells and in tumor biopsies. 2-NBDG displays excitation/emission maxima of 475/550 nm, respectively.
Uses
2-NBDG is a fluorescent glucose uptake indicator, used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry.
storage
Store at -20°C
References
1) Yoshioka?et al. (1996),?A novel fluorescent derivative of glucose applicable to the assessment of glucose uptake activity of Escherichia coli; Biochim. Biophys. Acta,?1289?5 2) Yamada?et al. (2000),?Measurement of glucose uptake and intracellular calcium concentration in single, living, pancreatic beta-cells; J. Biol. Chem.,?275?22278 3) Loaiza?et al. (2003),?Glutamate triggers rapid glucose transport stimulation in astrocytes as evidenced by real-time confocal microscopy; J. Neurosci.,?23?7337
2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE Preparation Products And Raw materials
Raw materials
Preparation Products
2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE Suppliers
Global( 131)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 +86-13986145403 | info@fortunachem.com | China | 5989 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
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2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE
2-NBDG
2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose
2-NBDG min. 95%
2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose, 90%, mixed Isomers
2-NBD-Glucose
2-NBDG [2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose] *CAS#: 186689-07-6*
2-NBDG,2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose
NBD-GLUCOSE
D-Glucose, 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-
2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose >=97% (HPLC)
2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE (NBDG)
Alitretinoin Impurity 14
186689-07-6