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ChemicalBook >> CAS DataBase List >>(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride

(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride

(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride Structure
(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride structure
CAS No.
188416-35-5
Chemical Name:
(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride
Synonyms
N-2;6-Chloro Voriconazole;Voriconazole Impurity 9;Voriconazole Impurity 90;rac-6-Chloro Voriconazole;Voriconazole intermediate;Voriconazole Impurity 9 HCl;Voriconazole Intermediate V5;Voriconazole 6-Chloro Racemate;Voriconazole (RS,SR)-6-Chloro Impurity
CBNumber:
CB1197794
Molecular Formula:
C16H13ClF3N5O
Molecular Weight:
383.76
MDL Number:
MFCD08063925
MOL File:
188416-35-5.mol
MSDS File:
SDS
Last updated:2023-05-15 10:43:55
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(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride Properties

Melting point 183-187°C
Boiling point 529.9±60.0 °C(Predicted)
Density 1.51
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 11.44±0.29(Predicted)
color Off-White
CAS DataBase Reference 188416-35-5(CAS DataBase Reference)

(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological T2978-23 N2- 188416-35-5 5mg $425 2021-12-16 Buy
Usbiological 279415 N-2- 188416-35-5 25mg $446 2021-12-16 Buy
Usbiological 165574 N2- 188416-35-5 100mg $446 2021-12-16 Buy
Usbiological 267939 N2- 188416-35-5 5mg $460 2021-12-16 Buy
Usbiological 457871 N-2- 188416-35-5 1mg $496 2021-12-16 Buy
Product number Packaging Price Buy
T2978-23 5mg $425 Buy
279415 25mg $446 Buy
165574 100mg $446 Buy
267939 5mg $460 Buy
457871 1mg $496 Buy

(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

An achiral intermediate of Voriconazole (V760000).

(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride synthesis

188416-28-6
86404-63-9
188416-35-5
Synthesis of (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride from 6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine and 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone

(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone (2R,3S/2S,3R)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Voriconazole

(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride Suppliers

Global( 168)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49390 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21149 58
Shandong Hengshannuode Pharmaceutical Technology Co., Ltd. 		+8615065888978 admin@hsnordpharma.com China 92 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17367 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Standardpharm Co. Ltd. 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Shandong Hengshannuode Pharmaceutical Technology Co., Ltd. 		58
SIMAGCHEM CORP 		58

View Lastest Price from (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride pictures 2022-09-27 (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride
188416-35-5
 US $0.00 / kg 1kg 99% 1000kg henan kanbei chemical co.,ltd
Voriconazole Intermediate V5 pictures 2022-09-15 Voriconazole Intermediate V5
188416-35-5
 US $30.00-28.00 / Kg 1Kg 99.0% up 50 tons per month Xinxiang Hongqi District Houyuan Trading Co.,Ltd
(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride pictures 2019-07-06 (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride
188416-35-5
 US $7.00 / kg 1kg 99% 100KG Career Henan Chemical Co

188416-35-5((2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride)Related Search:

(FORMYLMETHYLENE)TRIPHENYLPHOSPHORANE Fluorocytosine Uracil Silver sulfadiazine Cytosine
Triphenylphosphine 2-Phenylphenol Sulfadiazine Voriconazole 4-Chloro-6-ethyl-5-fluoropyrimidine
(trans)-6-Chloro-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol 4-Ethyl-5-fluoropyrimidine 6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine Voriconazole Impurity 53 1,2,4-Triazole
2-Chloro-2',4'-difluoroacetophenone Pyrimidine, 4-bromo-6-(1-bromoethyl)-5-fluoro- (2R,3S/2S,3R)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

1of4

6-Chloro-α-(2,4-difluorophenyl)-5-fluoro-β-Methyl-α-(1H-1,2,4-triazol-1-ylMethyl)-4-pyriMidineethanol 4-PyriMidineethanol, 6-chloro-a-(2,4-difluorophenyl)-5-fluoro-b-Methyl-a-(1H-1,2,4-triazol-1-ylMethyl)- (2R,3S/2S,3R)-3-(4-CHLORO-5-FLUORO PYRIMIDIN-6-YL)-2-(2,4-DIFLUOROPHENYL)-1-(1H-1,2,4-TRIAZOL-1-YL) Voriconazole (RR,SS)-6-Chloro IMpurity (2S,3R)-3-(6-chloro-5-fluoropyriMidin-4-yl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride 6-Chloro Voriconazole Voriconazole (RS,SR)-6-Chloro Impurity N-2 (2R,3S/2S,3R)-3-(4-CHLORO-5-FLUORO-6-PYRIMIDINYL)-2-(2,4-DIFLUOROPHENYL)-1-(1H-1,2,4-TRIAZOL-1-YL)-2-BUTANOL HCL (2R,3S/2S,3R)-3-(4-CHLORO-5-FLUORO-6-PYRIMIDINYL)-2-(2,4-DIFLUOROPHENYL)-1-(1H-1,2,4-TRIAZOL-1-YL)-2-BUTANOL HYDROCHLORIDE (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)-1- (1H- (2r,3s/2s,3r)-3-(4-Chloro-5-Fluoro-6-Pyrimidinyl)-2-(2,4-Difluorophenyl)-1-(1h-1,2,4-Triazol- 1-Yl)-2- Butanol Hydrochloride (2R,3S/2S,3R)-3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol- 1-yl)-2- butanol hydrochloride (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)-1- (1H-1,2,4-triazol-1-yl)-2-butanol hydrochloride ( N-2 step) (2R,3S/2S,3R)-3-(4-chloro-5-fluoro-6-pyrimidinyl)-2- (2,4-difluorophenyl)-1-(1H-1,2,4-trazol-1-yl)-2-butanol hydrochloride ( For Voriconazole ) (2R,3S/2S,3R)-3-(4-CHLORO-5-FLUORO-6-PYRIMIDINYL)-2-(2,4-DIFLUOROPHENYL) (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)- rac-6-Chloro Voriconazole (2R,3S/2S,3R)-3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanolhydrochlo (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol 3-(6-Chloro-5-fluoropyriMidin-4-yl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride (2R.3S/2S.3R) -3-(4-CHLORO-5-FLUOROPYRIMIDIN-6-YL)-2 -(2,4-D IFLUOROPHENYL)-1-(1H-1,2,4-TRIAZOL-1-YL) BUTAN-2-OL HYDROCHL Voriconazole Impurity 9 HCl Voriconazole Impurity 9 Voriconazole (RR,β)-6-Chloro Impurity-rac-6-Chloro Voriconazole Voriconazole 6-Chloro Racemate 4-Pyrimidineethanol, 6-chloro-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)- (2R,3S/2S,3R)-3-(4-CHLORO-5-FLUOROPYRIMIDIN-6-YL)-2-(2,4-DIFLUOROPHENYL)-1-(1H-1,2,4-TRIAZOL-1-YL)BUTAN-2-OL 2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride Voriconazole intermediate (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride 188416-35-5 Voriconazole (RR,β)-6-Chloro Impurity-rac-6-Chloro Voriconazole Voriconazole Intermediate V5 6-Chloro-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol m-Phenylenediamine-