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PICROTOXININ

PICROTOXININ
PICROTOXININ structure
CAS No.
17617-45-7
Chemical Name:
PICROTOXININ
Synonyms
PICROTOXININ;Yellowmouth Dutchmanspipe Root;6a-beta,8as*,8b-beta,9r*))-6-beta;ahydro-2a-hydroxy-8b-methyl-9-(1-methylethenyl)-,(1ar-(1a-alpha,2a-beta,3-bet
CBNumber:
CB7420980
Molecular Formula:
C15H16O6
Formula Weight:
292.28
MOL File:
17617-45-7.mol

PICROTOXININ Properties

Melting point:
203-205°C
alpha 
D17 +4.4° (c = 4.28 in abs alc), +3.49° (c = 7.57 in acetone)
Boiling point:
354.22°C (rough estimate)
Density 
1.2207 (rough estimate)
refractive index 
1.4359 (estimate)
form 
neat
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  T+
Risk Statements  25-28
Safety Statements  13-20-45-36/37-28
RIDADR  3172
WGK Germany  3
RTECS  PC5150000
HazardClass  6.1(a)
PackingGroup  I
Toxicity LD50 i.p. in mice: 3 mg/kg (Jarboe)
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

PICROTOXININ price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P8390 Picrotoxinin 17617-45-7 250mg $177 2018-11-20 Buy
Sigma-Aldrich Y0001528 Picrotoxinin European Pharmacopoeia (EP) Reference Standard 17617-45-7 y0001528 $179 2018-11-23 Buy

PICROTOXININ Chemical Properties,Uses,Production

Enzyme inhibitor

These neurotoxic GABAA receptor antagonists, consisting of a nearly 1:1 mixture of picrotoxinin, (FW = 292.29 g/mol; CAS 17617-45-7) and picrotin (FW = 310.30 g/mol; CAS 124-87-8), is a bitter-tasting (hence the Greek prefix picros) principle, also known as cocculin, from fishberry seeds (Anamirta cocculus) and the Philippine bayating (Tinomiscium philippinense). Picrotoxin binds to the chloride channel of the receptor without displacing g-aminobutyric acid. Picrotoxin is highly toxic, exerting both stimulant and convulsant effects, and care must be exercised when handling this agent.

PICROTOXININ Preparation Products And Raw materials

Raw materials

Preparation Products


PICROTOXININ Suppliers

Global( 26)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
Shanghai Tauto Biotech Co., Ltd 0086-21-51320588
0086-21-51320502 export2@tautobiotech.com China 3575 66
ChemStrong Scientific Co.,Ltd 0755 66853366
0755 28363542 sales@chem-strong.com; China 15618 56
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 QQ:2851167785
028-81705658 2851167785@qq.com China 3008 56
Sigma-Aldrich 021-61415566 800-819-3336(Tel) 400-620-3333(Mobile)
orderCN@merckgroup.com China 28681 80
Shanghai Uteam Biotechnology Co., Ltd. 400-0909-005 021-69955236-807
021-69955236-807 lj80414@hotmail.com China 5185 55
Shanghai Biological Technology Development Co., Ltd. 400-0909-005 021-65211385-102
021-65211385 lj80414@hotmail.com China 5186 55
Shanghai Jizhi Biochemical Technology Co. Ltd. 400-900-4166
1514189587@qq.com China 52529 58
Shenzhen Xinyaoxiong Industrial Co. Ltd. 0755-33204565 Sales QQ:2280077800(WeChat)
Advantage suppliers add cooperation QQ:577116998 szxys126@126.com China 54478 58
Chengdu Peter-like Biotechnology Co., Ltd. 028-81700200
2850505130@qq.com China 2236 58

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