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Metoprolol tartrate

β1 receptor blocker Uses Hazards & Safety Information
Metoprolol tartrate
Metoprolol tartrate structure
Chemical Name:
Metoprolol tartrate
Molecular Formula:
Formula Weight:
MOL File:

Metoprolol tartrate Properties

Melting point:
Boiling point:
695.37°C (rough estimate)
1.1946 (rough estimate)
refractive index 
1.5300 (estimate)
Flash point:
storage temp. 
Desiccate at RT
H2O: soluble50mg/mL
white to off-white
Water Solubility 
Soluble in water (>1000 mg/ml), methanol (>500 mg/ml), chloroform (496 mg/ml), ethanol (31 mg/ml at 25°C), and DMSO (100 mg/ml at 25°C).
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
56392-17-7(CAS DataBase Reference)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25
Safety Statements  7-16-36/37-45-24/25
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  3
RTECS  UB7450100
HS Code  29225090
Toxicity LD50 in female mice, male rats (mg/kg): 118, ~90 i.v.; 2090, 3090 orally (Bodin)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P311 Call a POISON CENTER or doctor/physician.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Metoprolol tartrate price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 80337 (±)-Metoprolol (+)-tartrate salt analytical standard 56392-17-7 100mg $50.7 2018-11-13 Buy
Sigma-Aldrich 1441301 Metoprolol tartrate United States Pharmacopeia (USP) Reference Standard 56392-17-7 200mg $352.8 2018-11-13 Buy
Alfa Aesar J61920 Metoprolol tartrate, 98+% 56392-17-7 5g $59.9 2018-11-13 Buy
Alfa Aesar J61920 Metoprolol tartrate, 98+% 56392-17-7 25g $301 2018-11-13 Buy
Cayman Chemical 21165 Metoprolol (tartrate) ≥98% 56392-17-7 10mg $29 2018-11-19 Buy

Metoprolol tartrate Chemical Properties,Uses,Production

β1 receptor blocker

Metoprolol tartrate is a selective β1-adrenergic receptor blocker,oral absorption is rapid  and complete,it is used for the treatment of hypertension, angina pectoris, myocardial infarction, hypertrophic cardiomyopathy, aortic dissection, cardiac arrhythmia, hyperthyroidism, cardiac neurosis and other diseases. In recent years, it is also used for ther treatment of heart failure, which can reduce mortality. In unstable/non-ST-segment elevation myocardial infarction and acute myocardial infarction  control guiding principles developed by American Heart Association , effect of metoprolol tartrateare is clearly recognized. In the past, concerns about β-blocker therapy caused hypotension is too large, and for the consideration that there may be racial differences between Asians in β-blocker use and the West, patients with treatment of β-blockers in China is  fewer  , the use of β-blockers is in lower dose.
Metoprolol tartrate has a weaker membrane stability and it has no intrinsic sympathomimetic activity, and in comparison with similar drugs commonly used in clinical propranolol ,in addition to the advantages of β1-blocker on its pharmacodynamic,it also has its pharmacokinetic kinetics  advantages, such as relatively weak first-pass effect compared with propranolol, simple metabolic pathways, most pharmacologically inactive metabolites and the like.


Hypertensive medication.

Hazards & Safety Information

Category: toxic substances
Toxicity grading: Middle  poisoning
Acute toxicity: oral -rat LD50: 5500 mg/kg; Oral-Mouse LD50: 1500 mg/kg
Flammability and hazard characteristics: It is combustible; fire decomposition produces toxic nitrogen oxide gases
Storage Characteristics: Ventilated, low-temperature ,dry storeroom.
Extinguishing agent: Water, carbon dioxide, dry powder, sandy soil.

Chemical Properties

White or almost white, crystalline powder or colourless crystals.


A ? selective aryloxypropanolamine andrenergic antagonist. Used in the treatment of a variety of cardiovascular disorder. Antihypertensive; antianginal; antiarrhythmic (class II)


A β1 selective aryloxypropanolamine andrenergic antagonist. Used in the treatment of a variety of cardiovascular disorder. Antihypertensive; antianginal; antiarrhythmic (class II).


alpha(1)-adrenergic blocker


A b1-Adrenergic blocker

brand name

Lopressor (Novartis).

Biological Activity

Selective β 1 -adrenoceptor antagonist (K i values are 47, 2960 and 10100 nM for β 1 , β 2 and β 3 adrenoceptors respectively). Inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo .

Metoprolol tartrate Preparation Products And Raw materials

Raw materials

Preparation Products

Metoprolol tartrate Suppliers

Global( 217)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 21930 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32457 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114 CHINA 6374 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038 CHINA 3623 58
career henan chemical co
+86-371-86658258 CHINA 20516 58
Kono Chem Co., Ltd
+86-132 8924 6953 CHINA 2144 58
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 23982 58
(323) 306-3136
(626) 453-0409 United States 8409 58

View Lastest Price from Metoprolol tartrate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-15 Metoprolol tartrate
US $1.00 / kg 1kg 99% Customized career henan chemical co

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