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Production description Introduction Uses
1-Propanol structure
Chemical Name:
Optal;albacol;n-C3H7OH;PROPANOL;FEMA 2928;ai3-16115;Propanole;Propanoli;1-PROPANOL;n-Propano1
Molecular Formula:
Formula Weight:
MOL File:

1-Propanol Properties

Melting point:
-127 °C(lit.)
Boiling point:
97 °C(lit.)
0.804 g/mL at 25 °C(lit.)
vapor density 
2.1 (vs air)
vapor pressure 
10 mm Hg ( 147 °C)
refractive index 
n20/D 1.384(lit.)
Flash point:
59 °F
storage temp. 
Store at RT.
H2O: passes test
Relative polarity
7 (200g/l, H2O, 20℃)
Resembles that of ethyl alcohol.
explosive limit
Water Solubility 
λ: 220 nm Amax: ≤0.40
λ: 240 nm Amax: ≤0.071
λ: 275 nm Amax: ≤0.0044
JECFA Number
Exposure limits
TLV-TWA (200 ppm); (500 mg/m3); STEL 250 ppm (625 mg/m3); IDLH 4000 ppm.
Stable. May form peroxides in contact with air. Incompatible with alkali metals, alkaline earths, aluminium, oxidizing agents, nitro compounds. Highly flammable. Vapour/air mixtures explosive.
CAS DataBase Reference
71-23-8(CAS DataBase Reference)
NIST Chemistry Reference
EPA Substance Registry System
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
  • NFPA
Hazard Codes  F,Xi
Risk Statements  11-41-67
Safety Statements  7-16-24-26-39
RIDADR  UN 1274 3/PG 2
WGK Germany  1
RTECS  UH8225000
Autoignition Temperature 700 °F
HazardClass  3
PackingGroup  II
HS Code  29051200
Hazardous Substances Data 71-23-8(Hazardous Substances Data)
Toxicity LD50 orally in rats: 1.87 g/kg (Smyth)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P370+P378 In case of fire: Use … for extinction.
P405 Store locked up.
P403+P235 Store in a well-ventilated place. Keep cool.

NFPA 704

Diamond Hazard Value Description
1 0
HEALTH   1 Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride)
FIRE  3 Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone)
REACT   0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)

(NFPA, 2010)

1-Propanol price More Price(60)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 24135 1-Propanol ≥99% (GC), purum 71-23-8 1l-r $56 2018-11-20 Buy
Sigma-Aldrich 1570406 1-Propanol United States Pharmacopeia (USP) Reference Standard 71-23-8 3amp $348 2018-11-13 Buy
TCI Chemical P0491 1-Propanol >99.5%(GC) 71-23-8 25mL $20 2018-11-22 Buy
TCI Chemical P0491 1-Propanol >99.5%(GC) 71-23-8 500mL $23 2018-11-22 Buy
Alfa Aesar 022932 1-Propanol, HPLC Grade, 99% min 71-23-8 *4x1L $153 2018-11-16 Buy

1-Propanol Chemical Properties,Uses,Production



1-propanol is the compound with the hydrogen atom in the propane molecules being replaced by hydroxyl group. Because the hydroxyl group can substitute the hydrogen atoms contained in the carbons in the two terminals of carbon chain or middle carbon, thus generating two isomers, n-propyl alcohol and isopropyl alcohol.
The chemical property of the 1-propanol is similar to that of ethanol. It is the byproduct during the process of the methanol synthesis from carbon monoxide and hydrogen. At room temperature and normal pressure, it appears as colorless transparent liquid with fragrance odor. In industry, it is prepared through the reaction between ethylene, carbon monoxide and hydrogen under high pressure and cobalt catalysis; alternatively through the hydration of propylene under the action of sulfate or through the catalytic hydrogenation of acetone. It is commonly used as a solvent with irritating effect on the eyes and mucosa. Inhalation of propyl alcohol steam can lead to dizziness, headache and vomiting, etc.


1Propanol is colorless transparent liquid, with ethanol-like smell, combustible. Soluble in acetone and benzene, miscible with a variety of common organic solvents (e.g., ethers, esters, acids, ketones, and other alcohols). It occurs in nature in crude fusel oils and as fermentation and decomposition products of various vegetables, used mainly as solvent. Azeotropics are formed with a variety of compounds, including aromatics, esters, amines, and ketones (See table below). When the product is oxidized, it can produce propionaldehyde and propionic acid, depending on the reaction conditions and the catalyst; it can form an ester with acid; it can form sodium alkoxide with active metal and be used as organic synthesis catalyst.
  Azeotropic mixture:
Binary azeotropic mixture
The other chemical water carbon tetrachloride benzene cyclohexane toluene n-hexane nitromethane
content (%) of 1-propanol 71.69 11.5 17.1 18.5 50.0 40 51.6
azeotropic points 87.72°C 72.80°C 77.10°C 74.69°C 92.60°C 73.10°C 89.09°C

Ternary azeotropic mixture
The other two chemicals water, carbon tetrachloride water, benzene water, cyclohexane
content (%) of these two chemicals 5.0, 84.0 8.6, 82.4 8.5, 81.5
azeotropic points 65.4℃ 68.5℃ 66.6℃


The propanols are used mainly as solvents for coatings; in antifreeze compositions and household and personal products; and as chemical intermediates for the production of esters, amines, and other organic derivatives. As a solvent, 1-propanol is used principally in printing inks, paint, cosmetics, pesticides, and insecticides.
1-Propanol is used commercially to produce glycol ethers. These are characterized by dual functionality, which imparts high solvency, chemical stability, and water compatibility.

Chemical Properties

Colorless liquid; odor similar to ethanol. Soluble in water, alcohol, and ether.


A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.


1-Propanol is used in making n-propyl acetate; and as a solvent for waxes, resins, vegetable oils, and flexographic printing ink. It is produced from the fermentation and spoilage of vegetable matter.


propanol: Either of two alcohols with the formula C3H7OH. Propan-1- ol is CH3CH2CH2OH and propan-2-ol is CH3CH(OH)CH3. Both are colourless volatile liquids. Propan-2-ol is used in making propanone (acetone).


As a solvent for resins and cellulose esters, etc.


ChEBI: The parent member of the class of propan-1-ols that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group.

General Description

A clear colorless liquid with a sharp musty odor like rubbing alcohol. Flash point 53-77°F. Autoignites at 700°F. Vapors are heavier than air and mildly irritate the eyes, nose, and throat. Density approximately 6.5 lb / gal. Used in making cosmetics, skin and hair preparations, pharmaceuticals, perfumes, lacquer formulations, dye solutions, antifreezes, rubbing alcohols, soaps, window cleaners, acetone and other chemicals and products.

Air & Water Reactions

Highly flammable. Water soluble.

Reactivity Profile

1-Propanol reacts with alkali metal, nitrides and strong reducing agents to give flammable and/or toxic gases. Reacts with oxoacids and carboxylic acids to form esters plus water. Converted by oxidizing agents to propanal or propionic acid. May initiate the polymerization of isocyanates and epoxides. Incompatible with strong oxidizing agents .


Flammable, dangerous fire risk. Explosive limits in air 2–13%. Toxic by skin absorption. Eye and upper respiratory tract irritant. Questionable carcinogen.

Health Hazard

Contact with eyes is extremely irritating and may cause burns. Vapors irritate nose and throat. In high concentrations, may cause nausea, dizziness, headache, and stupor.

Health Hazard

Target organs: skin, eyes, gastrointestinal tracts, and respiratory system. Toxic routes: ingestion, inhalation, and skin contact.
LD50 value, oral (rats): 5400 mg/kg (NIOSH1986)
LD50 value, skin (rabbits): 6700 mg/kg(NIOSH 1986)
Ingestion causes headache, drowsiness,abdominal cramps, gastrointestinal pain,ataxia, nausea, and diarrhea. Eye contactproduces irritation. It may cause dermatitison repeated skin contact. Although thetoxicity of 1-propanol is low, at a highconcentration it may produce a narcoticeffect, as well as irritation of the eyes, nose,and throat..

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Fire Hazard

Flash Point (°F): 81 ℃, 77 ℃; Flammable Limits in Air (%): 2.1-13.5; Fire Extinguishing Agents: Carbon dioxide for small fires, and alcohol foam for large fires; Fire Extinguishing Agents Not To Be Used: Water may be ineffective; Special Hazards of Combustion Products: Not pertinent; Behavior in Fire: Not pertinent; Ignition Temperature (°F): 700; Electrical Hazard: Class I, Group D; Burning Rate: 2.9 mm/min.

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Safety Profile

Poison by subcutaneous route. Moderately toxic by inhalation, ingestion, intraperitoneal, and intravenous routes. A skin and severe eye irritant. Questionable carcinogen with experimental carcinogenic data. Mutation data reported. A flammable liquid and dangerous fire hazard when exposed to heat, flame, or oxidizers. Explosive in the form of vapor when exposed to heat or flame. Ignites on contact with potassium-tert- butoxide. Dangerous upon exposure to heat or flame; can react vigorously with oxidizing materials. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes.

Potential Exposure

n-Propyl alcohol is used as as solvent in lacquers, dopes; to make cosmetics; dental lotions; clea- ners, polishes, and pharmaceuticals; as a surgical antiseptic. It is a solvent for vegetable oils, natural gums and resins; rosin, shellac, certain synthetic resins; ethylcellulose, and butyral; as a degreasing agent; as a chemical intermediate.

First aid

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, includ- ing resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medi- cal attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit.


UN1274, n-Propanol, Hazard Class: 3; Labels: 3-Flammable liquid.

Purification Methods

The main impurities in n-propyl alcohol are usually water and 2-propen-1-ol, reflecting the commercial production by hydration of propene. Water can be removed by azeotropic distillation either directly (azeotrope contains 28% water) or by using a ternary system, e.g. by also adding *benzene. Alternatively, for removal of gross amounts of water, reflux over CaO for several hours is desirable, followed by distillation and a further drying. To obtain more nearly anhydrous alcohol, suitable drying agents are firstly NaOH, CaSO4 or K2CO3, then CaH2, aluminium amalgam, magnesium activated with iodine, or a small amount of sodium. Alternatively, the alcohol can be refluxed with n-propylsuccinate or phthalate in a method similar to the one described under EtOH. Allyl alcohol is removed by adding bromine (15mL/L) and then fractionally distilling from a small amount of K2CO3. Propionaldehyde, also formed in the bromination, is removed as the 2,4-dinitrophenylhydrazone. n-Propyl alcohol can be dried down to 20ppm of water by passage through a column of pre-dried molecular sieves (type 3 or 4A, heated for 3hours at 300o) in a current of nitrogen. Distillation from sulfanilic or tartaric acids removes impurities. Albrecht [J Am Chem Soc 82 3813 1960] obtained spectroscopically pure material by heating with charcoal to 50-60o, filtering and adding 2,4-dinitrophenylhydrazine and a few drops of conc H2SO4. After standing for several hours, the mixture is cooled to 0o, filtered and distilled in a vacuum. Gold and Satchell [J Chem Soc 1938 1963] heated n-propyl alcohol with 3-nitrophthalic anhydride at 76-110o for 15hours, then recrystallised the resulting ester from H2O, *benzene/pet ether (b 100-120o)(3:1), and *benzene. The ester was hydrolysed under reflux with aqueous 7.5M NaOH for 45minutes under nitrogen, followed by distillation (also under nitrogen). The fraction with b 87-92o is dried with K2CO3 and stirred under reduced pressure in the dark over 2,4-dinitrophenylhydrazine, then freshly distilled. Also purify it by adding 2g NaBH4 to 1.5L of alcohol, gently flushing with argon and refluxing for 1day at 50o. Then 2g of freshly cut sodium (washed with propanol) is added and refluxed for one day, and finally distilled, taking the middle fraction [Jou & Freeman J Phys Chem 81 909 1977]. [Beilstein 1 IV 1413.]


Vapors may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, perox- ides, permanganates, perchlorates, chlorine, bromine, fluo- rine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. n-Propanol reacts with alkali metal, nitrides and strong reducing agents to give flammable and/ or toxic gases. Reacts with oxoacids and carboxylic acids to form esters plus water. Converted by oxidizing agents to propanal or propionic acid. May initiate the polymerization of isocyanates and epoxides

Waste Disposal

Dissolve or mix the material with a combustible solvent and burn in a chemical incinera- tor equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

1-Propanol Preparation Products And Raw materials

Raw materials

Preparation Products

1-Propanol Suppliers

Global( 270)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32651 55
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254 CHINA 20243 58
career henan chemical co
+86-371-86658258 CHINA 19997 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333
021-50323701 China 25106 65
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) China 40395 62
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 China 30291 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 / 800-988-0390
021-67121385 China 24648 81
Beijing dtftchem Technology Co., Ltd. 13651141086; 86(10)60275028、60275820
86 (10) 60270825 China 1438 62
Energy Chemical 021-58432009 / 400-005-6266
021-58436166-800 China 44187 61

View Lastest Price from 1-Propanol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-17 1-Propanol
US $1.00 / kg 1kg 99% 100KG career henan chemical co

1-Propanol Spectrum

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