Ethyltriphenylphosphonium bromide
- CAS No.
- 1530-32-1
- Chemical Name:
- Ethyltriphenylphosphonium bromide
- Synonyms
- TEP;Ethyl triphenyl phosphine bromide;ethyltriphenylphosphanium bromide;AD182;ETPPB;tbepb;ETPPBR;Ethyl triphenyl pho;TEP (oniuM coMpound);Antioxidants Impurity 15
- CBNumber:
- CB7752854
- Molecular Formula:
- C20H20BrP
- Molecular Weight:
- 371.25
- MDL Number:
- MFCD00011838
- MOL File:
- 1530-32-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Ethyltriphenylphosphonium bromide 99% | E50604 | 25g | $49.1 |
| Ethyltriphenylphosphonium bromide 99% | E50604 | 100g | $146 |
| Ethyltriphenylphosphonium Bromide >98.0%(HPLC)(T) | E0382 | 25g | $24 |
| Ethyltriphenylphosphonium Bromide >98.0%(HPLC)(T) | E0382 | 100g | $64 |
| Ethyltriphenylphosphonium bromide, 99% 99% | 15-2301 | 25g | $59 |
| More product size | |||
| Melting point | 203-205 °C(lit.) |
|---|---|
| Boiling point | 240℃[at 101 325 Pa] |
| Density | 1.38[at 20℃] |
| vapor pressure | 0-0.1Pa at 20-25℃ |
| Flash point | 200 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | 174g/l soluble |
| form | Crystalline Powder |
| color | White to off-white |
| Water Solubility | 120 g/L (23 ºC) |
| Sensitive | Hygroscopic |
| BRN | 3599630 |
| InChI | 1S/C20H20P.BrH/c1-2-21(18-12-6-3-7-13-18,19-14-8-4-9-15-19)20-16-10-5-11-17-20;/h3-17H,2H2,1H3;1H/q+1;/p-1 |
| InChIKey | JHYNXXDQQHTCHJ-UHFFFAOYSA-M |
| SMILES | [Br-].CC[P+](c1ccccc1)(c2ccccc2)c3ccccc3 |
| LogP | -0.69--0.446 at 35℃ |
| CAS DataBase Reference | 1530-32-1(CAS DataBase Reference) |
| FDA UNII | R85V84UL5V |
| EPA Substance Registry System | Phosphonium, ethyltriphenyl-, bromide (1530-32-1) |
| UNSPSC Code | 12352002 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H318-H412 | |||||||||
| Precautionary statements | P264-P270-P273-P280-P301+P310-P305+P351+P338 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn,N,Xi | |||||||||
| Risk Statements | 22-51/53-36/37/38-21/22 | |||||||||
| Safety Statements | 61-36/37/39-26-36 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 2 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29310095 | |||||||||
| Storage Class | 6.1D - Non-combustible acute toxic Cat.3 toxic hazardous materials or hazardous materials causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Aquatic Chronic 3 Eye Dam. 1 |
|||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
Ethyltriphenylphosphonium bromide price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | E50604 | Ethyltriphenylphosphonium bromide 99% | 1530-32-1 | 25g | $49.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | E50604 | Ethyltriphenylphosphonium bromide 99% | 1530-32-1 | 100g | $146 | 2026-04-30 | Buy |
| TCI Chemical | E0382 | Ethyltriphenylphosphonium Bromide >98.0%(HPLC)(T) | 1530-32-1 | 25g | $24 | 2026-04-30 | Buy |
| TCI Chemical | E0382 | Ethyltriphenylphosphonium Bromide >98.0%(HPLC)(T) | 1530-32-1 | 100g | $64 | 2026-04-30 | Buy |
| Strem Chemicals | 15-2301 | Ethyltriphenylphosphonium bromide, 99% 99% | 1530-32-1 | 25g | $59 | 2026-04-30 | Buy |
Ethyltriphenylphosphonium bromide Chemical Properties,Uses,Production
Chemical Properties
White to off-white crystalline powder
Uses
suzuki reaction
Uses
Ethyltriphenylphosphonium Bromide (ETPB) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.
- Ethyltriphenylphosphonium bromide acts as a reactant in the synthesis of D-amino acids from L-cysteine-derived thiazolidines, Leiodolide A through aldol reactions and Horner-Wadsworth-Emmons olefination.
- It is also used in the preparation of cycloalkanoindolines through diastereoselective intramolecular inimo-ene reactions.
- it is used as a reagent in solid-state metathesis polycondensation to prepare alkyl-dipropenylthiophene monomers.
- Mizoroki-Heck cyclization and cascading Tsuji-Trost cyclization reactions.
Uses
PTC catalyst
Uses
Ethyltriphenylphosphonium Bromide is used as a wittig reagent. Ethyltriphenylphosphonium Bromide and other phosphonium salts show antiviral activity.
Flammability and Explosibility
Not classified
reaction suitability
reaction type: C-C Bond Formation
Synthesis
74-96-4
603-35-0
1530-32-1
In a 1500 mL three-necked flask, 54 g (0.5 mol) of ethyl bromide, 210 g (0.8 mol) of triphenylphosphine and 1000 mL of toluene were added sequentially. A reflux condenser tube was installed, magnetic stirring was turned on and the reaction was heated to reflux state and kept at reflux for 10 hours. Upon completion of the reaction, the reaction system was naturally cooled to 50 °C and a large amount of white solid was observed to precipitate. The solid product was collected by filtration through a Brinell funnel and the filter cake was washed with toluene three times (50 mL each time). The resulting solid was transferred to a vacuum drying oven and dried at 50 °C until constant weight, resulting in 170.4 g of ethyltriphenylphosphonium bromide in 91.8% yield.
Purification Methods
Recrystallise it from H2O and dry it in high vacuum at 100o. IR has bands at 1449, 1431 and 997cm-1 . [Wittig & Wittenberg Justus Liebigs Ann Chem 606 1 1957, Bergmann & Dusza J Org Chem 23 1245 1958, Beilstein 16 IV 982.]
References
[1] Journal of Fluorine Chemistry, 2002, vol. 113, # 2, p. 177 - 183
[2] Pharmazie, 1999, vol. 54, # 1, p. 26 - 30
[3] Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1989, vol. <2> 38, # 12, p. 2553 - 2556
[4] Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1989, vol. <2> 38, # 12, p. 2789 - 2792
[5] Journal of the American Chemical Society, 1980, vol. 102, p. 2437
Ethyltriphenylphosphonium bromide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5235 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13843 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21590 | 55 |
| JingJiang Connect Chemical manufacturing Co., Ltd. | 0523-80501690 15252623102 | andy@katchemical.com | CHINA | 59 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
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View Lastest Price from Ethyltriphenylphosphonium bromide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-30 | Ethyltriphenylphosphonium bromide
1530-32-1
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2026-04-17 | Ethyl(triphenyl)phosphonium bromide
1530-32-1
|
US $50.00-10.00 / kg | 1kg | 99%，Electronic grade(Single metal impurity≤ 100ppb) or pharmaceutical grade | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2026-03-20 | Ethyltriphenylphosphonium bromide
1530-32-1
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Ethyltriphenylphosphonium bromide
1530-32-1
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Ethyl(triphenyl)phosphonium bromide
1530-32-1
- US $50.00-10.00 / kg
- 99%，Electronic grade(Single metal impurity≤ 100ppb) or pharmaceutical grade
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- Ethyltriphenylphosphonium bromide
1530-32-1
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
