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Octenidine dihydrochloride

CAS No.
70775-75-6
Chemical Name:
Octenidine dihydrochloride
Synonyms
Octenidine hydrochloride;SOT360;Octenidine DiHCl;Otinidine hydrochloride;ocenidine dihydrochloride;OCTENIDINE DIHYDROCHLORIDE;Ortinidine dihydrochloride;TRANS-2-NONENAL 18829-56-6;OctenidineDihydrochloride>Octenidine dihydrochloride 97%
CBNumber:
CB7879838
Molecular Formula:
C36H64Cl2N4
Molecular Weight:
623.82616
MDL Number:
MFCD01938808
MOL File:
70775-75-6.mol
Last updated:2024-08-21 22:41:43

Octenidine dihydrochloride Properties

Melting point 215-217℃
Density 1.046[at 20℃]
vapor pressure 0Pa at 25℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Soluble in dimethyl sulfoxide and methanol.
form Solid
color White to Off-White
Water Solubility 14.2g/L at 20℃
Merck 14,6754
Stability Hygroscopic
InChIKey SMGTYJPMKXNQFY-UHFFFAOYSA-N
SMILES [N+]1(CCCCCCCCCC[N+]2C=CC(NCCCCCCCC)=CC=2)=CC=C(NCCCCCCCC)C=C1.[Cl-].[Cl-]
LogP 1.5 at 23℃
FDA UNII U84956NU4B

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P280-P301+P312-P362+P364
HS Code  2933399990
NFPA 704
1
2 0

Octenidine dihydrochloride price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical O0388 Octenidine Dihydrochloride >98.0%(HPLC)(N) 70775-75-6 1g $29 2024-03-01 Buy
TCI Chemical O0388 Octenidine Dihydrochloride >98.0%(HPLC)(N) 70775-75-6 5g $114 2024-03-01 Buy
Alfa Aesar H62257 Octenidine dihydrochloride, 98% 70775-75-6 1g $34.9 2024-03-01 Buy
Alfa Aesar H62257 Octenidine dihydrochloride, 98% 70775-75-6 5g $137 2024-03-01 Buy
TRC O239150 Octenidine Dihydrochloride 70775-75-6 5g $120 2021-12-16 Buy
Product number Packaging Price Buy
O0388 1g $29 Buy
O0388 5g $114 Buy
H62257 1g $34.9 Buy
H62257 5g $137 Buy
O239150 5g $120 Buy

Octenidine dihydrochloride Chemical Properties,Uses,Production

Description

The antiseptic agent octenidine dihydrochloride (OCT) was developed by Sterling Winthrop (WIN41464-2) in the 1980s as an alternative to the anti-plaque agent CHX and successfully tested in vitro and in vivo. OCT has a broad spectrum of activity with similar effectiveness against Gram-negative and Gram-positive bacteria, fungi, and yeasts. Moreover, it has been shown that it may effectively interfere with the co-aggregation of dental plaque microbial colonizers without disturbing the normal, healthy oral flora. In a standardized comparison of antimicrobial activity ofthe antiseptic agents triclosan, polyvinylpyrrolidone-iodine, OCT, polyhexamethylene biguanide, and Chlorhexidine digluconat (CHX) using the min-imal effective concentration and minimum bactericidal con-centration, OCT was the most effective active agent of alltested antimicrobial substances. In other studies, the antibacterial and antiplaque efficacy of OCT was equal to or even greater than that of CHX[1].

Uses

Octenidine is an antiseptic (topical). Octenidine is a cationic surfactant and bis-(dihydropyridinyl)-decane derivative.

Uses

Octenidine dihydrochloride is used as a antiseptic for skin, mucous Membranes and wounds.

Application

Octenidine dihydrochloride is a cationic antiseptic that belongs to the bispyridine class of chemicals. Its action is binding to anionic structures of the cell membrane, further bursting the membrane. It has activity against Gram-positive and Gram-negative bacteria. It was effective in oral hygiene, preventing plaque and gingivitis, as a whole body wash for methicillin-resistant S. aureus decolonization and skin disinfection of premature newborn infants. Octenidine concentrations of less than 1.5 μM (0.94 μg/mL) reduced each microbial population by more than 99% within 15 minutes. Staphylococcus epidermidis was the most susceptible of the test organisms, and E. coli and Candida albicans were the least susceptible. Octenidine was more active than chlorhexidine against each test strain. This antiseptic has not been established in veterinary medicine for skin preparation but is used for wound cleansing.

Flammability and Explosibility

Not classified

References

[1] A. Welk. “Antibacterial and antiplaque efficacy of a commercially available octenidine-containing mouthrinse.” Clinical Oral Investigations 20 1 (2015): 1469–1476.

2162-98-3
64690-19-3
70775-75-6
Synthesis of Octenidine dihydrochloride from 1,10-Dichlorodecane and N-octylpyridin-4-amine

Octenidine dihydrochloride Preparation Products And Raw materials

Global( 273)Suppliers
Supplier Tel Email Country ProdList Advantage
Jinan Jianfeng Chemical Co., Ltd
+8615562555968 info@pharmachemm.com China 247 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5873 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5866 58
Hebei Weimiao Import and Export Trade Co., Ltd.
+undefined19948166995 sale01@hbweimiao.com China 73 58
Sigma Audley
+86-15937194204 +86-18126314766 nova@sh-teruiop.com China 491 58
airuikechemical co., ltd.
+undefined86-15315557071 sales02@sdzhonghuimaterial.com China 983 58
Hebei Saisier Technology Co., LTD
+86-18400010335 +86-18034520335 admin@hbsaisier.cn China 1009 58
Hebei Longbang Technology Co., LTD
+86-18032476855 +86-18032476855 admin@hblongbang.com China 942 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21667 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9354 55

View Lastest Price from Octenidine dihydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Octenidine Dihydrochloride pictures 2024-09-19 Octenidine Dihydrochloride
70775-75-6
US $10.70 / kg 10kg 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
Octenidine dihydrochloride pictures 2024-09-19 Octenidine dihydrochloride
70775-75-6
US $7.00 / g 5g 99% 20t Jinan Jianfeng Chemical Co., Ltd
Octenidine dihydrochloride pictures 2024-09-13 Octenidine dihydrochloride
70775-75-6
US $6.00 / KG 1KG 99% 20TONS Hebei Longbang Technology Co., Ltd

Octenidine dihydrochloride Spectrum

N,N'-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis(1-octanamine) dihydrochloride N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride OCTENIDINE DIHYDROCHLORIDE N,N'-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-1-octanaMine Hydrochloride N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylaMMoniuM) dichloride 1-OctanaMine,N,N'-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-, hydrochloride (1:2) ocenidine dihydrochloride -(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride Octenidine dihydrochloride 97% SOT360 Octenidine DiHCl OctenidineDihydrochloride> 1,1'-(Decane-1,10-diyl)bis(N-octylpyridin-4(1H)-imine) dihydrochloride N,N'-(1,1'-(decane-1,10-diyl)bis(pyridin-1(1H)-yl-4(1H)-ylidene))bis(octan-1-amine) dihydrochloride Octenidine dihydrochloride USP/EP/BP Octenidine Dihydrochloride DISCONTINUED, offer O239150 Pharmaceutical Intermediate Octenidine HCl/Octenidine Hydrochloride CAS 70775-75-6 N-octyl-1-[10-[4-(octylamino)pyridin-1-ium-1-yl]decyl]pyridin-1-ium-4-amine N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylam... Octenidine dihydrochlorideQ: What is Octenidine dihydrochloride Q: What is the CAS Number of Octenidine dihydrochloride Q: What is the storage condition of Octenidine dihydrochloride TIANFUCHEM--70775-75-6--High purity N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride factory price Octenidine hydrochloride Ortinidine dihydrochloride Otinidine hydrochloride TRANS-2-NONENAL 18829-56-6 Octenidine Dihydrochloride,98% Octenidine Dihydrochloride, ≥ 98.0% 1,1'-(Decane-1,10-diyl)bis(N-octylpyridin-4(1H)-imine) dihydrochloride N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride N,N'-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-1-octanaMine Hydrochloride 70775-75-6 76775-75-6 C36H62N42HCl Amines Heterocycles Intermediates & Fine Chemicals Pharmaceuticals 70775-75-6