MELPERONE
- CAS No.
- 3575-80-2
- Chemical Name:
- MELPERONE
- Synonyms
- FG 5111;Buronil;Melperon;metylperon;Flubuperone;Melperone >Melperone,Inhibitor,inhibit;Melperone (base and/or unspecified salts);4-Fluoro-γ-(4-Methylpiperidino)butyrophenone;γ-(4-Methylpiperidino)-p-fluorobutyrophenone
- CBNumber:
- CB81011889
- Molecular Formula:
- C16H22FNO
- Molecular Weight:
- 263.35
- MDL Number:
- MFCD00867737
- MOL File:
- 3575-80-2.mol
| Melting point | 78.0 to 82.0 °C |
|---|---|
| Boiling point | bp0.1 120-125° |
| Density | 1.046±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 41.67 mg/mL (158.23 mM) |
| pka | 9.34±0.10(Predicted) |
| form | powder to crystal |
| color | White to Light yellow to Light orange |
| Merck | 14,5827 |
| FDA UNII | J8WA3K39B7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H332-H319-H312 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P264-P280-P305+P351+P338-P337+P313P-P280-P302+P352-P312-P322-P363-P501 |
| HS Code | 2933.39.3100 |
MELPERONE price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M2622 | Melperone >95.0%(GC) | 3575-80-2 | 25mg | $116 | 2024-03-01 | Buy |
| TCI Chemical | M2622 | Melperone >95.0%(GC) | 3575-80-2 | 100mg | $338 | 2024-03-01 | Buy |
| Chem-Impex | 38067 | Melperone,95%(GC) 95%(GC) | 3575-80-2 | 100MG | $400.96 | 2021-12-16 | Buy |
| AK Scientific | E830 | Melperone | 3575-80-2 | 100mg | $538 | 2021-12-16 | Buy |
| Chem-Impex | 38067 | Melperone,95%(GC) 95%(GC) | 3575-80-2 | 25MG | $123.2 | 2021-12-16 | Buy |
MELPERONE Chemical Properties,Uses,Production
Originator
Eunerpan,Nordmark,W. Germany,1965
Definition
ChEBI: 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone is an aromatic ketone.
Manufacturing Process
A solution or dispersion consisting of 20.1 g (0.1 mol) of γ-chloro-pfluorobutyrophenone, 19.8 g (0.2 mol) of 4-methylpiperidine and 0.1 g of potassium iodide in 150 ml toluene is heated in a sealed glass tube for 15 hours at 100°C to 110°C. The potassium iodide and the 4-methylpiperidine hydrochloride formed in the reaction are separated by filtration and the solvent removed from the filtrate by evaporation in vacuum on a steam bath. The residue is distilled and the fraction obtained at 120°C to 125°C and at a pressure lower than 0.1 mm Hg is collected. The base is dissolved in ether and the 4-fluoro-γ-(4-methylpiperidino)-butyrophenone precipitated as the hydrochloride. The reaction product is purified by recrystallization in ethanol/ether.
Yield 22.0 g (73% of theory). MP 209°C to 211°C.
Therapeutic Function
Neuroleptic
MELPERONE Preparation Products And Raw materials
MELPERONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24539 | 81 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28398 | 80 |
3575-80-2(MELPERONE)Related Search:
1of4