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BUTEIN

BUTEIN structure

CAS No.: 487-52-5

Chemical Name:: BUTEIN

Synonyms: BUTANOL;2',3,4,4'-TETRAHYDROCHALCONE;(2E)-;BUTEIN;CS-5675;BUTEIN(P);CCG208298;BUTEIN(SH);Butein >AC 1NQY7L)

CBNumber:: CB8136455

Molecular Formula:: C15H12O5

Molecular Weight:: 272.25

MDL Number:: MFCD00017300

MOL File:: 487-52-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 03:20:45

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BUTEIN Properties

Melting point	216°C
Boiling point	560.9±50.0 °C(Predicted)
Density	1.483±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: >50 mg/mL
form	solid
pka	7.44±0.35(Predicted)
color	yellow
InChI	1S/C15H12O5/c16-10-3-4-11(14(19)8-10)12(17)5-1-9-2-6-13(18)15(20)7-9/h1-8,16,18-20H/b5-1+
InChIKey	AYMYWHCQALZEGT-ORCRQEGFSA-N
LogP	2.405 (est)
CAS DataBase Reference	487-52-5(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	4WVS5M0LGF
UNSPSC Code	85151701
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Safety Statements	22-24/25
WGK Germany	3
HS Code	29145090
Storage Class	11 - Combustible Solids

BUTEIN price More Price(75)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	72795	Butein analytical standard	487-52-5	10mg	$281	2026-04-30	Buy
Sigma-Aldrich	203987	Butein - CAS 487-52-5 - Calbiochem A cell-permeable, reversible, substrate competitive, plant polyphenol that acts as a specific protein tyrosine kinase inhibitor.	487-52-5	5MG	$272	2022-05-15	Buy
TCI Chemical	B3803	Butein >98.0%(HPLC)	487-52-5	1g	$258	2026-04-30	Buy
TCI Chemical	B3803	Butein >98.0%(HPLC)	487-52-5	100mg	$117	2026-04-30	Buy
Cayman Chemical	15371	Butein ≥95%	487-52-5	1mg	$36	2026-04-30	Buy

Product number	Packaging	Price	Buy
72795	10mg	$281	Buy
203987	5MG	$272	Buy
B3803	1g	$258	Buy
B3803	100mg	$117	Buy
15371	1mg	$36	Buy

BUTEIN Chemical Properties, Uses, Production

Chemical Properties

Yellow Solid

Uses

Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-κB in activated human mast cells: suppression of tumor necrosis factor-α, interleukin (IL)-6, and IL-8. Anti-inflammatory agent

Definition

ChEBI: A chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'.

General Description

Butein (2′,3,4,4′-tetrahydroxychalcone) is a chalcone and a flavonoid, that is produced in plants. It is a plant polyphenol and a bioactive constituent, that is extracted from the heartwood ofDalbergia odorifera, Caragana jubata andRhus vernicifluastokes, and the stem bark of cashews (Semecarpus anacardium).

Biochem/physiol Actions

Butein exhibit several pharmacological activities, such as anti-oxidant and anti-inflammatory activity. It stimulates apoptotic cell death of human cervical cancer cells. It has therapeutic potentials for chronic diseases, including liver tuberculosis, obesity, diabetes and hypertension. Butein can repress migration and invasion of bladder, breast and pancreatic cancer cells.

BUTEIN Preparation Products And Raw materials

Raw materials

Preparation Products

BUTEIN Suppliers

Global Suppliers ( 266)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Chembest Research Laboratories Limited	021-20908456	sales@BioChemBest.com	China	5996	61
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
BioBioPha Co., Ltd.	0871-65217109	y.liu@mail.biobiopha.com	China	5641	65
T&W GROUP	021-61551611 13296011611	contact@trustwe.com	China	9884	58
Chengdu Biopurify Phytochemicals Ltd.	+86-028-82633397 18982077548	cwb1@biopurify.cn	China	2376	60
Haoyuan Chemexpress Co., Ltd.	021-58950125	info@chemexpress.com	China	7545	61
TOKYO CHEMICAL INDUSTRY CO., LTD.	03-36680489	Sales-JP@TCIchemicals.com	Japan	28364	80

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Chembest Research Laboratories Limited	61
TCI (Shanghai) Development Co., Ltd.	81
Chemsky（shanghai）International Co.,Ltd.	50
BioBioPha Co., Ltd.	65
T&W GROUP	58
Chengdu Biopurify Phytochemicals Ltd.	60
Haoyuan Chemexpress Co., Ltd.	61
TOKYO CHEMICAL INDUSTRY CO., LTD.	80

View Latest Price from BUTEIN manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-10-16	Butein 487-52-5		20MG	98%min	30kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
2023-02-24	Butein 487-52-5		20mg	≥98%(HPLC)	100 g	Shanghai Standard Technology Co., Ltd.
2020-01-10	Butein 487-52-5	$1.00	1KG	≥98%	20 tons	Career Henan Chemical Co

Butein
487-52-5
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

Butein
487-52-5
$0.00
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

Butein
487-52-5
$1.00
≥98%
Career Henan Chemical Co

BUTEIN Spectrum

BUTEIN(487-52-5)¹HNMR

487-52-5 (BUTEIN) Related Search:

Butin Pterostilbene viomycin Nodakenetin 4-(4-Nitrophenyl)-1-butanol

4-Chlorobutyl acetate 4-AMINO-1-BUTANOL L-Methioninol 4-BROMO-3,3,4,4-TETRAFLUORO-1-BUTANOL Chalcone

4-CHLORO-1-BUTANOL 4-(tert-ButoxycarbonylaMino)-1-butanol 4-Amino-2-butanol 7,3',4'-Trihydroxyflavanone Hexafluoro-2-methylisopropanol

4-Ethylamino-1-butanol Tetrahydroionol DL-Methioninol

1of4

(E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one 2',3,4,4'-Tetrahydroxychalcone BUTEIN(P) 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-, (2E)- Butein 2',3,4,4'-Tetrahydroxychalcone 2-[(E)-2-(2-aminophenyl)ethenyl]-5-methyl-quinolin-8-ol 2-[(E)-2-(2-aminophenyl)ethenyl]-5-methylquinolin-8-ol 2-[(E)-2-(2-aminophenyl)vinyl]-5-methyl-8-quinolinol 2-[(E)-2-(2-aminophenyl)vinyl]-5-methyl-quinolin-8-ol 2-[2-(2-aminophenyl)ethenyl]-5-methyl-quinolin-8-ol 2-[2-(2-aminophenyl)ethenyl]-5-methylquinolin-8-ol 2-[2-(2-aminophenyl)vinyl]-5-methyl-8-quinolinol 2-[2-(2-aminophenyl)vinyl]-5-methyl-quinolin-8-ol 2-[2-(2-aminophenyl)vinyl]-5-methylquinolin-8-ol BUTEIN 2',4',3,4-TETRAHYDROXYCHALCONE 2',3,4,4'-TETRAHYDROXYCHALCONE 3,4,2',4'-TETRAHYDROXYCHALCONE 1-(2,4-DIHYDROXYPHENYL)-3-(3,4-DIHYDROXYPHENYL)-2-PROPEN-1-ONE 1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propene-1-one (E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one 2',3,4,4'-Tetrahydroxy-trans-chalcone Einecs 207-659-5 BUTEIN(SH) BUTEIN WITH HPLC (2E)- Butein - CAS 487-52-5 - Calbiochem Butein > Butein Butein (E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one AC 1NQY7L) Butein (NSC-652892 CCG208298 CS-5675 2',3,4,4'-TETRAHYDROCHALCONE BUTANOL PDE4,Epidermal growth factor receptor,Inhibitor,EGFR,MAPK,ErbB-1,Apoptosis,Autophagy,FoxO3a,inhibit,cell,SIRT1,Phosphodiesterase (PDE),ERK,PKB,Butein,AKT,HeLa,HER1,p38,HepG2 (2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one Butein, c-Met and EGFR tyrosine kinase inhibitor Butein-CAS 487-52-5 Butein, 10 mM in DMSO 487-52-5 Receptor Tyrosine Kinase Inhibitors Epidermal Growth Factor Receptor (EGFR) and Src BioChemical Cell Biology Cell Signaling and Neuroscience Kinase/Phosphatase Biology Aromatics Inhibitors Intermediates & Fine Chemicals Pharmaceuticals