2,3-Dichlorobenzoyl cyanide
- CAS No.
- 77668-42-9
- Chemical Name:
- 2,3-Dichlorobenzoyl cyanide
- Synonyms
- 2,3-Dichlorobenzoylc;Lamotrigine Impurity 5;Lamotrigine Impurity 10;Lamotrigine Impurity 25;2,3-DichloroBenzoylNitrile;2,3-dichlorobenozyl cyanide;2,3-DICHLOROBENZOYL CYANIDE;Dichlorobenzoyl Lamotrigine;2,3-Dichlorobenzoyl cyanide, 98%;(2,3-dichlorophenyl)oxoacetonitrile
- CBNumber:
- CB8147167
- Molecular Formula:
- C8H3Cl2NO
- Molecular Weight:
- 200.02
- MDL Number:
- MFCD00792559
- MOL File:
- 77668-42-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2,3-DichlorobenzoylNitrile | D432250 | 50g | $1185 |
| 2,3-DichlorobenzoylNitrile | 56831 | 100g | $2450 |
| 2,3-Dichlorobenzoyl cyanide 97% | 084725 | 500g | $405 |
| 2,3-Dichlorobenzoyl cyanide | FD33387 | 100g | $480 |
| 2,3-Dichlorobenzoylcyanide | J50793 | 1g | $10 |
| More product size | |||
| Melting point | 52-53 °C(Solv: ligroine (8032-32-4)) |
|---|---|
| Boiling point | 309°C |
| Density | 1.446 |
| Flash point | 141°C |
| storage temp. | Sealed in dry,Room Temperature |
| form | solid |
| color | Cream |
| InChI | InChI=1S/C8H3Cl2NO/c9-6-3-1-2-5(8(6)10)7(12)4-11/h1-3H |
| InChIKey | FIBBFBXFASKAON-UHFFFAOYSA-N |
| SMILES | C1(C(=O)C#N)=CC=CC(Cl)=C1Cl |
| CAS DataBase Reference | 77668-42-9(CAS DataBase Reference) |
| FDA UNII | 3K95NM9ZHZ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300-H311+H331-H315-H319-H400 |
| Precautionary statements | P501-P261-P273-P270-P271-P264-P280-P391-P337+P313-P305+P351+P338-P361+P364-P332+P313-P301+P310+P330-P302+P352+P312-P304+P340+P311-P403+P233-P405 |
| Hazard Codes | Xi |
| RIDADR | UN3439 |
| Hazard Note | Irritant |
| HazardClass | 6.1 |
| HS Code | 2926907090 |
| Limited Quantities | 100ml (liquid) or 0.5 Kg (solid) |
| Excepted Quantities | Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml) |
2,3-Dichlorobenzoyl cyanide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | D432250 | 2,3-DichlorobenzoylNitrile | 77668-42-9 | 50g | $1185 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 56831 | 2,3-DichlorobenzoylNitrile | 77668-42-9 | 100g | $2450 | 2021-12-16 | Buy |
| Matrix Scientific | 084725 | 2,3-Dichlorobenzoyl cyanide 97% | 77668-42-9 | 500g | $405 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD33387 | 2,3-Dichlorobenzoyl cyanide | 77668-42-9 | 100g | $480 | 2021-12-16 | Buy |
| AK Scientific | J50793 | 2,3-Dichlorobenzoylcyanide | 77668-42-9 | 1g | $10 | 2021-12-16 | Buy |
2,3-Dichlorobenzoyl cyanide Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
2,3-Dichlorobenzoyl cyanide is an impurity of Lamotrigine (L173250), an anticonvulsant that is used in the treatment of bipolar and depression.
Synthesis
2905-60-4
143-33-9
77668-42-9
1. Synthesis of 2,3-dichlorobenzoyl cyanide 2,3-Dichlorobenzoyl chloride (20.0 g, 100 mmol) and cuprous iodide (I) (0.90 g, 4.7 mmol) were suspended in acetonitrile (50 mL) and stirred at room temperature until a yellow homogeneous solution was formed. Solid sodium cyanide (5.15 g, 110 mmol) was added slowly with a controlled addition time of 5-8 hours. After addition, stirring of the reaction mixture was continued for 1 h. The reaction progress was monitored by HPLC. The resulting inorganic salt (mainly NaCl) was removed by filtration and the filter cake was washed with acetonitrile (15 mL). Acetonitrile was removed by distillation under reduced pressure (~150 mbar). Sodium metabisulfite (Na2S2O3, 0-4 g, 3 mmol) was added to remove trace iodine. Finally, the product was purified by vacuum distillation (jacket temperature 140°C, boiling point 115°C/2 mbar) to give 2,3-dichlorobenzoyl cyanide in >80% yield and 100% purity (as determined by analytical HPLC) with a melting point of 60°C.
References
[1] Patent: WO2008/19798, 2008, A1. Location in patent: Page/Page column 12
2,3-Dichlorobenzoyl cyanide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| RongNa Biotechnology Co.,Ltd | +86-86-13583358881 +8618560316533 | Brad@rongnabiotech.com | China | 3388 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +86-15350851019; +8615350851019 | admin@86-ss.com | China | 999 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29833 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
View Lastest Price from 2,3-Dichlorobenzoyl cyanide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-27 | 2,3-Dichlorobenzoyl cyanide
77668-42-9
|
US $10.00 / ASSAYS | 1ASSAYS | 99% | 1 ton | RongNa Biotechnology Co.,Ltd | |
 |
2026-01-21 | 2,3-Dichlorobenzoyl cyanide
77668-42-9
|
US $980.00-750.00 / kg | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2025-10-13 | 2,3-Dichlorobenzoyl cyanide
77668-42-9
|
US $2.00-6.00 / kg | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD |
-
- 2,3-Dichlorobenzoyl cyanide
77668-42-9
- US $10.00 / ASSAYS
- 99%
- RongNa Biotechnology Co.,Ltd
-
- 2,3-Dichlorobenzoyl cyanide
77668-42-9
- US $980.00-750.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- 2,3-Dichlorobenzoyl cyanide
77668-42-9
- US $2.00-6.00 / kg
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
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