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4-Chloro-3-(trifluoromethyl)phenyl isocyanate

4-Chloro-3-(trifluoromethyl)phenyl isocyanate
4-Chloro-3-(trifluoromethyl)phenyl isocyanate structure
CAS No.
327-78-6
Chemical Name:
4-Chloro-3-(trifluoromethyl)phenyl isocyanate
Synonyms
Sorafenib INT1;4-chloro-a,a,a-trifluoro-M-tolyl ester;4-Chloro-α,α,α-trifluoro-m-tolyl isocyanate;3-TRIFLUOROMETHYL-4-CHLORO-PHENYL ISOCYANATE;4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL ISOCYANATE;4-Chloro-3-(trifluoroMethoxy)phenyl Isocyanate;1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene;4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL ISOCYANATE 98%;4-Chloro-3-(trifluoromethyl)phenyl isocyanate,98%;Benzene, 1-chloro-4-isocyanato-2-(trifluoromethyl)-
CBNumber:
CB8262374
Molecular Formula:
C8H3ClF3NO
Formula Weight:
221.56
MOL File:
327-78-6.mol

4-Chloro-3-(trifluoromethyl)phenyl isocyanate Properties

Melting point:
40-42 °C(lit.)
Boiling point:
86-90 °C14 mm Hg(lit.)
Density 
1.4720 (estimate)
Flash point:
211 °F
form 
Low Melting Solid, Powder or Chunks
color 
White to yellow
Sensitive 
Moisture Sensitive
BRN 
522032
CAS DataBase Reference
327-78-6(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  20/21/22-36/37-36/37/38-42-20/22
Safety Statements  7-26-27-37/39-36/37/39-45-23
RIDADR  UN 2206 6.1/PG 3
WGK Germany  3
Hazard Note  Harmful/Moisture Sensitive
HazardClass  6.1
PackingGroup  III
HS Code  29291090
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning P261, P271, P304+P340, P312
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger P261, P285, P304+P341, P342+P311,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to..…

4-Chloro-3-(trifluoromethyl)phenyl isocyanate price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 374881 4-Chloro-3-(trifluoromethyl)phenyl isocyanate 98% 327-78-6 5g $72 2018-11-13 Buy
TCI Chemical C2778 4-Chloro-3-(trifluoromethyl)phenyl Isocyanate >98.0%(GC) 327-78-6 5g $72 2018-11-22 Buy
TCI Chemical C2778 4-Chloro-3-(trifluoromethyl)phenyl Isocyanate >98.0%(GC) 327-78-6 25g $239 2018-11-22 Buy
Alfa Aesar L12016 4-Chloro-3-(trifluoromethyl)phenyl isocyanate, 97% 327-78-6 5g $75.8 2018-11-13 Buy

4-Chloro-3-(trifluoromethyl)phenyl isocyanate Chemical Properties,Uses,Production

Chemical Properties

White solid or melt

Uses

4-Chloro-3-(trifluoromethyl)phenyl isocyanate may be used in the synthesis of: N-(5′-deoxy-3′-O-tert-butyldimethylsilyl-β-D-thymidin-5′-yl)-N′-(4-chloro-3-trifluoromethylphenyl)-thiourea [1,3-bis(4-chloro-α,α,α-trifluoro-m-tolyl)urea] trans-1-(4-chloro-3-trifluoromethyl-phenyl)-3-(4-hydroxy-cyclohexyl)-urea

4-Chloro-3-(trifluoromethyl)phenyl isocyanate Preparation Products And Raw materials

Raw materials

Preparation Products


4-Chloro-3-(trifluoromethyl)phenyl isocyanate Suppliers

Global( 228)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106
+86 (576) 8169-6105 sales@frappschem.com China 887 50
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1530 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 fandachem@gmail.com CHINA 2464 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070;product@chemlin.com.cn
product@chemlin.com.cn CHINA 3015 60
Jinan Jianfeng Chemical Co., Ltd
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Chemwill Asia Co.,Ltd.
86-21-51086038
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View Lastest Price from 4-Chloro-3-(trifluoromethyl)phenyl isocyanate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 4-Chloro-3-(trifluoromethyl)phenyl isocyanate
327-78-6
US $1.00 / KG 1G 98% 100KG career henan chemical co
2018-08-15 4-Chloro-3-(trifluoromethyl)phenyl isocyanate
327-78-6
US $1.00 / KG 1KG 99% 1000KG career henan chemical co
2018-07-19 4-Chloro-3-(trifluoromethyl)phenyl isocyanate(327-78-6)
327-78-6
US $10.00-10.00 / G 10UG 99% 1000kg/month Hebei Chisure Biotechnology Co., Ltd.

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