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CYCLO(-HIS-PRO)

CYCLO(-HIS-PRO) structure

CAS No.: 53109-32-3

Chemical Name:: CYCLO(-HIS-PRO)

Synonyms: Cyclo(HP);Cyclo(Pro-His);CYCLO(-HIS-PRO);HIS-PRO, CYCLIC;Cyclo-Pro-His-HO;CYCLO(HIS-PRO), >99%;Cyclo(histidyl-proline);Protirelin EP Impurity E;Cyclo(L-histidyl-L-proline);Nebivolol Impurity 10 Monomer

CBNumber:: CB8279260

Molecular Formula:: C11H14N4O2

Molecular Weight:: 234.25

MDL Number:: MFCD00133207

MOL File:: 53109-32-3.mol

Last updated:2023-05-18 11:31:04

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CYCLO(-HIS-PRO) Properties

Melting point	162-164 °C
Boiling point	659.3±48.0 °C(Predicted)
Density	1.41±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 1 mg/ml
form	A neat oil
pka	12.73±0.40(Predicted)
FDA UNII	Q10817UXVT

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
WGK Germany	3

CYCLO(-HIS-PRO) price More Price(13)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth Carbosynth	FC49257	Cyclo(L-His-L-Pro)	53109-32-3	25mg	$83.5	2021-12-16	Buy
ChemScene	CS-6320	Cyclo(his-pro)	53109-32-3	5mg	$90	2021-12-16	Buy
Biosynth Carbosynth	FC49257	Cyclo(L-His-L-Pro)	53109-32-3	50mg	$140.5	2021-12-16	Buy
ChemScene	CS-6320	Cyclo(his-pro)	53109-32-3	10mg	$150	2021-12-16	Buy
Biosynth Carbosynth	FC49257	Cyclo(L-His-L-Pro)	53109-32-3	100mg	$225	2021-12-16	Buy

Product number	Packaging	Price	Buy
FC49257	25mg	$83.5	Buy
CS-6320	5mg	$90	Buy
FC49257	50mg	$140.5	Buy
CS-6320	10mg	$150	Buy
FC49257	100mg	$225	Buy

CYCLO(-HIS-PRO) Chemical Properties,Uses,Production

Uses

Cyclo(L-histidyl-L-proline) is used in the pharmaceutical composition comprising cyclo(His-Pro) for preventing or treating obesity.

Definition

ChEBI: Cyclo(L-His-L-Pro) is a homodetic cyclic peptide resulting from the formal condensation of both the amino and acid groups of L-histidine with the acid and amino groups of L-proline. It is a metabolite of thyrotropin-releasing hormone (TRH). It has a role as a human blood serum metabolite, a dopamine uptake inhibitor and an anti-inflammatory agent. It is a homodetic cyclic peptide, a dipeptide, a pyrrolopyrazine and a member of imidazoles. It is functionally related to a L-histidine and a L-proline.

CYCLO(-HIS-PRO) Preparation Products And Raw materials

Raw materials

Preparation Products

CYCLO(-HIS-PRO) Suppliers

Global( 81)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9702	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58

Supplier	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	58
Career Henan Chemica Co	58
Finetech Industry Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
Chengdu Youngshe Chemical Co., Ltd.	58
LEAP CHEM CO., LTD.	58
TargetMol Chemicals Inc.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58

53109-32-3(CYCLO(-HIS-PRO))Related Search:

2,5-Dimethylpiperazine 1-Methylpiperazin-2-one DL-2-AMINOPROPIONIC ANHYDRIDE CYCLO(-ALA-ALA) CIS-2,5-DIMETHYLPIPERAZINE

CYCLO-(D-PRO-L-ALA-D-ALA-L-2-AMINO-8-OXO-9,10-EPOXYDECANOIC ACID),Cyclo[D-Pro-L-Ala-D-Ala-2-(6-oxo-6-oxiranylhexyl)-L-Gly-] Cyclo(L-Pro-L-Val-) CYCLO(-GLY-HIS) 1-ETHYL-2-METHYL-PIPERAZINE CYCLO(-GLY-PRO)

(S)-3-METHYL-2-KETOPIPERAZINE CYCLO(-ALA-GLY) HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE (+/-)-1,4-DIAZABICYCLO[4.4.0]DECANE (R)-HEXAHYDROPYRROLO[1,2-A]PYRAZIN-1(2H)-ONE

1-ETHYLPIPERAZIN-2-ONE hexahydropyrrolo[1,2-a]pyrazin-4(1H)-one (S)-1,4-DIAZABICYCLO[4.3.0]NONANE

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(3S,6S)-3-(3H-imidazol-4-ylmethyl)-1,4-diazabicyclo[4.4.0]decane-2,5-dione Histidylproline diketopiperazine histidylproline dioxopiperazine Cyclo-Pro-His-HO HIS-PRO, CYCLIC CYCLO(-HIS-PRO) Cyclo(histidyl-proline) CYCLO(HISTIDYL-PROLINE); HISTIDYLPROLINE DIKETOPIPERAZINE CYCLO(HIS-PRO), >99% Cyclo(his-pro),Cyclo(histidyl-proline),Histidylproline diketopiperazine, >99% Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1H-imidazol-4-ylmethyl)-, (3S,8aS)- Protirelin EP Impurity E 3-(1H-imidazol-5-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione Cyclo(L-histidyl-L-proline) (3S,8aS)-3-(1H-Imidazol-4-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione Cyclo(his-pro) (Cyclo(histidyl-proline)) Endogenous Metabolite,active,orally,inflammatory,inhibit,tyreotropin-releasing,stress,NF-κB,Cyclo(his-pro),hormone,Nuclear factor-κB,cyclic,Cyclo(hispro),Histidylproline diketopiperazine,Cyclo(histidyl-proline),dipeptide,Cyclo(his pro),Inhibitor,Nuclear factor-kappaB,responses Cyclo(HP) (3S,8aS)-3-[(4-Imidazolyl)methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione Nebivolol Impurity 10 Monomer Cyclo(Pro-His) 53109-32-3 Peptides Releasing Factors TRH Biochemicals and Reagents Amino Acids and Peptides BioChemical