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N-Boc-4-carboxymethoxy-piperidine

N-Boc-4-carboxymethoxy-piperidine Structure
N-Boc-4-carboxymethoxy-piperidine structure
CAS No.
161948-70-5
Chemical Name:
N-Boc-4-carboxymethoxy-piperidine
Synonyms
ST5313750;ASN 07731208;ASINEX-REAG BAS 07731208;1-Boc-4-Carboxymethoxy-Piperidine;N-Boc-4-carboxymethoxy-piperidine;(1-Boc-4-piperidinyloxy)acetic acid;2-[(1-Boc-4-piperidyl)oxy]acetic Acid;(1-Boc-4-piperidinyloxy)aceticacid,95%;(1-Boc-4-piperidinyloxy)acetic acid, 95%;(1-Boc-4-piperidinyloxy)acetic acid - [C0836]
CBNumber:
CB8317696
Molecular Formula:
C12H21NO5
Molecular Weight:
259.3
MDL Number:
MFCD02178987
MOL File:
161948-70-5.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:38
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N-Boc-4-carboxymethoxy-piperidine Properties

Melting point 105-107℃
Boiling point 406.7±35.0 °C(Predicted)
Density 1.17±0.1 g/cm3(Predicted)
storage temp. Store at room temperature
pka 3.42±0.10(Predicted)
Appearance White to off-white Solid
InChI InChI=1S/C12H21NO5/c1-12(2,3)18-11(16)13-6-4-9(5-7-13)17-8-10(14)15/h9H,4-8H2,1-3H3,(H,14,15)
InChIKey YHUAHIMRWSVXCN-UHFFFAOYSA-N
SMILES N1(C(OC(C)(C)C)=O)CCC(OCC(O)=O)CC1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi,T
Risk Statements  25
Safety Statements  45
HazardClass  IRRITANT
HS Code  2933399990
NFPA 704
0
2 0

N-Boc-4-carboxymethoxy-piperidine price More Price(56)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR962583 (1-Boc-4-piperidinyloxy)acetic acid 98% 161948-70-5 100mg $21 2026-06-04 Buy
Apolloscientific OR962583 (1-Boc-4-piperidinyloxy)acetic acid 98% 161948-70-5 250mg $24 2026-06-04 Buy
Apolloscientific OR962583 (1-Boc-4-piperidinyloxy)acetic acid 98% 161948-70-5 1g $56 2026-06-04 Buy
Apolloscientific OR962583 (1-Boc-4-piperidinyloxy)acetic acid 98% 161948-70-5 5g $213 2026-06-04 Buy
Apolloscientific OR962583 (1-Boc-4-piperidinyloxy)acetic acid 98% 161948-70-5 25g $963 2026-06-04 Buy
Product number Packaging Price Buy
OR962583 100mg $21 Buy
OR962583 250mg $24 Buy
OR962583 1g $56 Buy
OR962583 5g $213 Buy
OR962583 25g $963 Buy

N-Boc-4-carboxymethoxy-piperidine Chemical Properties,Uses,Production

Synthesis

1-BOC-4-ETHOXYCARBONYLMETHOXYPIPERIDINE

189889-45-0

N-BOC-4-CARBOXYMETHOXY-PIPERIDINE

161948-70-5

GENERAL STEPS: To a 100 mL round bottom flask was added tert-butyl 4-(2-ethoxy-2-oxoethoxy)piperidine-1-carboxylate (5.00 g, 17.4 mmol), sodium hydroxide (3.00 g, 75.0 mmol), water (20 mL), and ethanol (20 mL). The reaction mixture was stirred at room temperature for 48 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure to remove the solvent. The pH of the residue was adjusted with 3 mol/L hydrochloric acid solution to 2. Subsequently, the aqueous phase was extracted with ethyl acetate (2 x 20 mL), and the organic layers were combined and concentrated under reduced pressure to afford 4.00 g (89% yield) of 2-([1-[(tert-butoxy)carbonyl]piperidin-4-yl]oxy)acetic acid as an oil. Thin layer chromatography (TLC) analytical conditions: dichloromethane/methanol = 5/1, Rf = 0.4.

References

[1] Patent: WO2017/89390, 2017, A1. Location in patent: Page/Page column 97; 98
[2] European Journal of Medicinal Chemistry, 1999, vol. 34, # 5, p. 363 - 380
[3] Patent: WO2014/151958, 2014, A1. Location in patent: Paragraph 00290

N-Boc-4-carboxymethoxy-piperidine Preparation Products And Raw materials

Raw materials

1-Boc-4-ethoxycarbonylmethoxypiperidine Ethanol Water Sodium hydroxide

Preparation Products

N-Boc-4-carboxymethoxy-piperidine Suppliers

Global( 78)Suppliers
Supplier Tel Email Country ProdList Advantage
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9849 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Chengdu Firster Pharmaceutical Co., Ltd. 028-87078428 028-87074958 chengzhenyong@cdfirster.com China 2580 60
Shanghai AQBioPharma Co., Ltd. 13661411401 yinglv.que@aqbiopharma.com.cn China 2976 58
Shanghai Xingui Biotechnology Co., Ltd. 15121041756 xingui2022@126.com China 9985 58
SanoChem (Chengdu) Tech. Co., Ltd. 28-87999436 02887999436 sales@sano-chem.com China 3792 55
Chengdu J&B Technology Co., Ltd. 028-61186694 15608078506 609128801@qq.com China 853 55
Supplier Advantage
Alfa Aesar 84
Pure Chemistry Scientific Inc. 62
Adamas Reagent, Ltd. 59
Amatek Scientific Co. Ltd. 55
Bide Pharmatech Ltd. 60
Chengdu Firster Pharmaceutical Co., Ltd. 60
Shanghai AQBioPharma Co., Ltd. 58
Shanghai Xingui Biotechnology Co., Ltd. 58
SanoChem (Chengdu) Tech. Co., Ltd. 55
Chengdu J&B Technology Co., Ltd. 55

View Lastest Price from N-Boc-4-carboxymethoxy-piperidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-BOC-4-CARBOXYMETHOXY-PIPERIDINE pictures 2020-01-10 N-BOC-4-CARBOXYMETHOXY-PIPERIDINE
161948-70-5
 $6.00 1KG 98% 1kg, 5kg, 50kg Career Henan Chemical Co

N-Boc-4-carboxymethoxy-piperidine Spectrum

N-BOC-4-CARBOXYMETHOXY-PIPERIDINE(161948-70-5)1HNMR

161948-70-5(N-Boc-4-carboxymethoxy-piperidine)Related Search:

N-BOC-4-Hydroxypiperidine 4-METHOXYCARBONYLMETHOXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Ethyl 4-hydroxypiperidine-1-carboxylate Isopropyl 4-hydroxypiperidine-1-carboxylate 1-Boc-4-methoxypiperidine
1-Boc-3-Carboxymethoxy-Piperidine 1-Boc-3-(2-(Benzyloxy)-2-Oxoethoxy)Piperidine 1-Boc- 4-(2-Methoxy-2-Oxoethoxy)Piperidine 1-Boc-3-(2-tert-butoxy-2-oxoethoxy)piperidine 1-Boc- 4-(2-(Benzyloxy)-2-Oxoethoxy)Piperidine
3-Carboxymethoxy-piperidine-1-carboxylic acid tert-butyl ester 1-Boc-4-ethoxycarbonylmethoxypiperidine Benzyl-4-[N-Boc-piperidinoxy] acetate N-Boc-4-carboxymethoxy-piperidine (Piperidin-4-yloxy)-acetic acid

1of3

ASINEX-REAG BAS 07731208 1-Boc-4-Carboxymethoxy-Piperidine 4-CARBOXYMETHOXY-PIPERIDINE-1-CARBOXYLIC ACIDTERT-BUTYL ESTER 2-[(1-tert-Butoxycarbonyl-4-piperidyl)oxy]acetic acid (1-Boc-4-piperidinyloxy)acetic acid, 95% {[1-(tert-butoxycarbonyl)piperidin-4-yl]oxy}acetic acid 2-[[1-(tert-butoxy-oxomethyl)-4-piperidinyl]oxy]acetic acid 2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]oxyacetic acid 2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]oxyethanoic acid ASN 07731208 ST5313750 2-[[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinyl]oxy]acetate 1-Piperidinecarboxylic acid, 4-(carboxymethoxy)-, 1-(1,1-dimethylethyl) ester (1-Boc-4-piperidinyloxy)aceticacid,95% 2-[(1-Boc-4-piperidyl)oxy]acetic Acid (1-Boc-4-piperidinyloxy)acetic acid - [C0836] (1-Boc-4-piperidinyloxy)acetic acid N-Boc-4-carboxymethoxy-piperidine 161948-70-5 pharmacetical