BIS(2,2,2-TRIFLUOROETHYL) ETHER
- CAS No.
- 333-36-8
- Chemical Name:
- BIS(2,2,2-TRIFLUOROETHYL) ETHER
- Synonyms
- HFE;SF6539;SKL232;Idoklon;skf6539;Flurotyl;Indiklon;Indoklon;SKF 6539;SK&F-6539
- CBNumber:
- CB8723208
- Molecular Formula:
- C4H4F6O
- Molecular Weight:
- 182.06
- MDL Number:
- MFCD00010604
- MOL File:
- 333-36-8.mol
- MSDS File:
- SDS
Melting point | 25°C |
---|---|
Boiling point | 62-63 °C (lit.) |
Density | 1.404 g/mL at 25 °C (lit.) |
refractive index |
n |
Flash point | 35 °F |
storage temp. | Flammables area |
solubility | DMSO : ≥ 125 mg/mL (686.59 mM) |
form | clear liquid |
color | Colorless to Almost colorless |
Specific Gravity | 1.41 |
Merck | 14,4201 |
BRN | 1811927 |
CAS DataBase Reference | 333-36-8(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 9Z467FG2YK |
EPA Substance Registry System | HFE-356mff2 (333-36-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS02,GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H225-H315-H319-H335 | |||||||||
Precautionary statements | P210-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | F,Xi,T | |||||||||
Risk Statements | 11-36/37/38 | |||||||||
Safety Statements | 16-26-36 | |||||||||
RIDADR | UN 3271 3/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | KN3675000 | |||||||||
Hazard Note | Flammable/Toxic/Convulsant | |||||||||
HazardClass | 3.1 | |||||||||
PackingGroup | II | |||||||||
HS Code | 29091990 | |||||||||
NFPA 704 |
|
BIS(2,2,2-TRIFLUOROETHYL) ETHER price More Price(21)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 287571 | Bis(2,2,2-trifluoroethyl) ether 98% | 333-36-8 | 5g | $113 | 2024-03-01 | Buy |
TCI Chemical | B1293 | Bis(2,2,2-trifluoroethyl) Ether >99.0%(GC) | 333-36-8 | 1g | $59 | 2024-03-01 | Buy |
TCI Chemical | B1293 | Bis(2,2,2-trifluoroethyl) Ether >99.0%(GC) | 333-36-8 | 5g | $163 | 2024-03-01 | Buy |
TRC | B585665 | Bis(2,2,2-trifluoroethyl) Ether | 333-36-8 | 500mg | $70 | 2021-12-16 | Buy |
TRC | B585665 | Bis(2,2,2-trifluoroethyl) Ether | 333-36-8 | 50mg | $40 | 2021-12-16 | Buy |
BIS(2,2,2-TRIFLUOROETHYL) ETHER Chemical Properties,Uses,Production
Chemical Properties
clear colorless liquid
Originator
Indoklon ,Ohio Medical, US ,1964
Uses
Bis(2,2,2-trifluoroethyl) Ether is Prophylactic and/or therapeutic agent for Alzheimer''s disease.
Uses
Bis(2,2,2-trifluoroethyl) ether was used to diminish self-discharge of Li-S cells having both low- and high-sulfur-loading sulfur cathodes.
Uses
5HT agonist
Definition
ChEBI: Flurotyl is an ether.
Manufacturing Process
23 parts of sodium metal were placed in 300 parts of dry dioxane in a reactor equipped with an agitator and reflux condenser. The dioxane was heated to reflux while stirring.150 parts of 2,2,2-trifluoroethanol were added very slowly in the period of about 1 hour, or until the sodium was all reacted, to form sodium 2,2,2-trifluoroethylate. 250 parts of 2,2,2-trifluoroethyl ptoluenesulfonate prepared by reacting 2,2,2-trifluoroethanol with p
Flurothyl toluenesulfonyl chloride were placed in another reactor and heated to about 160° to 185°C. The solution of sodium 2,2,2-trifluoroethylate in dioxane was added very slowly over a period of about 1? hours. Bis(2,2,2-trifluoroethyl) ether formed continuously and distilled from the reactor with the dioxane into a cooled receiving vessel. The condensed effluent from the reactor was fractionally distilled, yielding 46.5 parts of products boiling at 55° to 73°C.
The crude product was washed successively with concentrated HCl, 62% H2SO4,concentrated H2SO4 and 5% NaOH solution. It was dehydrated over a drying agent and then refractionated in a still. 20 parts of bis(2,2,2trifluoroethyl) ether were recovered (BP 62.5° to 63.5°C).
brand name
Indoklon (Ohmeda).
Therapeutic Function
Central stimulant, Convulsant
BIS(2,2,2-TRIFLUOROETHYL) ETHER Preparation Products And Raw materials
Raw materials
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Preparation Products
BIS(2,2,2-TRIFLUOROETHYL) ETHER Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20393 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21687 | 55 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10247 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12846 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Allfluoro pharmaceutical co. ltd. | 021-26137118 +8615821363818 | sales@allfluoro.com | China | 5791 | 58 |
CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20356 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
View Lastest Price from BIS(2,2,2-TRIFLUOROETHYL) ETHER manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-04-27 | Fluorothyl
333-36-8
|
US $30.00-0.90 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | ||
2022-10-09 | BIS(2,2,2-TRIFLUOROETHYL) ETHER
333-36-8
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
- Fluorothyl
333-36-8
- US $30.00-0.90 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
- BIS(2,2,2-TRIFLUOROETHYL) ETHER
333-36-8
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
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