ChemicalBook >> CAS DataBase List >>(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME
(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME
- CAS No.
- 667463-85-6
- Chemical Name:
- (2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME
- Synonyms
- CS-1611;BIO-ACETOXIME;GSK-3 INHIBITOR X;GSK3 Inhibitor IX2;6-Bromoindirubin acetoxime;BIO-Acetoxime >=98% (HPLC);6-Bromoindirubin-3′-acetoxime;BIO-acetoxime(GSK-3 Inhibitor);BIO-acetoxime GSK3 Inhibitor IX2;BIO-acetoxime (GSK-3 Inhibitor X)
- CBNumber:
- CB8818870
- Molecular Formula:
- C18H12BrN3O3
- Molecular Weight:
- 398.21
- MDL Number:
- MFCD09037533
- MOL File:
- 667463-85-6.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H410 |
| Precautionary statements | P264-P270-P273-P301+P312-P391-P501 |
| Hazard Codes | Xn,N |
| Risk Statements | 22-50/53 |
| Safety Statements | 60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | 3 |
(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0531 | BIO-Acetoxime ≥98% (HPLC) | 667463-85-6 | 5mg | $171 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0531 | BIO-Acetoxime ≥98% (HPLC) | 667463-85-6 | 25mg | $656 | 2024-03-01 | Buy |
| Tocris | 3874 | BIO-acetoxime ≥98%(HPLC) | 667463-85-6 | 10 | $308 | 2021-12-16 | Buy |
| Tocris | 3874 | BIO-acetoxime ≥98%(HPLC) | 667463-85-6 | 1 | $148 | 2021-12-16 | Buy |
| TRC | B591760 | BIO-acetoxime | 667463-85-6 | 1mg | $55 | 2021-12-16 | Buy |
(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME Chemical Properties,Uses,Production
Uses
BIO-Acetoxime is a potent and selective GSK-3a/b inhibitor that reduces invasiveness of gliomas and extends animal survival in intracranial glioma models. It also induces Wnt signaling and inhibits CD8+ T cell effector differentiation.
Biological Activity
Selective GSK-3 α / β inhibitor (IC 50 values are 0.01, 2.4, 4.3 and 63 μ M for GSK-3 α / β , CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). Induces Wnt signaling and inhibits CD8+ T cell effector differentiation.
storage
Store at +4°C
(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 102)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 | 18522618860@163.com | China | 694 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
View Lastest Price from (2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-05 | (2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME
667463-85-6
|
US $1.00 / KG | 1KG | 95--99% | 1ton | Career Henan Chemical Co |
-
- (2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME
667463-85-6
- US $1.00 / KG
- 95--99%
- Career Henan Chemical Co
(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME
BIO-ACETOXIME
GSK-3 INHIBITOR X
(3Z)-3-[(3E)-3-[(Acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-2H-Indol-2-one
6-Bromoindirubin acetoxime
6-Bromoindirubin-3′-acetoxime
GSK3 Inhibitor IX2
BIO-acetoxime(GSK-3 Inhibitor)
(2Z,3E)-3-(Acetoxyimino)-6'-bromo-[2,3'-biindolinylidene]-2'-one
BIO-acetoxime GSK3 Inhibitor IX2
CS-1611
GSK3 INHIBITOR X6-BROMOINDIRUBIN-3'-ACETOXIME
BIO-acetoxime (GSK-3 Inhibitor X)
2H-Indol-2-one, 3-[(3E)-3-[(acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-, (3Z)-
BIO-Acetoxime >=98% (HPLC)
667463-85-6
Other enzyme inhibitors and activators