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4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE

4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE structure

CAS No.: 3223-07-2

Chemical Name:: 4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE

Synonyms: EVOMELA;MELPHALAN HCL;Melphalan HCl API;CB 3025 hydrochloride;MELPHALAN HYDROCHLORIDE;l-sarcolysinehydrochloride;Melphalan hydrochloride CRS;Melphalan for system suitability;phenylalaninemustardhydrochloride;Melphalan Hydrochloride (1379300)

CBNumber:: CB9105234

Molecular Formula:: C13H19Cl3N2O2

Molecular Weight:: 341.66

MDL Number:: MFCD01674304

MOL File:: 3223-07-2.mol

Last updated:2025-07-04 14:25:52

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4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE Properties

Melting point	175-178 °C
storage temp.	2-8°C
solubility	Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
Stability	Moisture Sensitive
InChI	InChI=1S/C13H18Cl2N2O2.ClH/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19;/h1-4,12H,5-9,16H2,(H,18,19);1H
InChIKey	OUUYBRCCFUEMLH-UHFFFAOYSA-N
SMILES	C1(=CC=C(CC(N)C(=O)O)C=C1)N(CCCl)CCCl.Cl
FDA UNII	1VXP4V453T
NCI Dictionary of Cancer Terms	Evomela; melphalan hydrochloride
NCI Drug Dictionary	Evomela
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08,GHS06
Signal word	Danger
Hazard statements	H330-H361-H340-H350-H310-H300
Precautionary statements	P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501-P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501
Toxicity	TDLo orl-hmn: 1200 mg/kg/5D-I:GIT CCROBU57,369,73

4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	Y0001158	Melphalan hydrochloride European Pharmacopoeia (EP) Reference Standard	3223-07-2	110 mg	$164	2025-07-31	Buy
TRC	M216901	MelphalanHydrochloride	3223-07-2	100mg	$105	2021-12-16	Buy
Biosynth Carbosynth	FM61588	Melphalan hydrochloride	3223-07-2	250mg	$125	2021-12-16	Buy
American Custom Chemicals Corporation	API0005250	MELPHALAN HYDROCHLORIDE 95.00%	3223-07-2	5MG	$502.94	2021-12-16	Buy
AK Scientific	4301CR	Melphalanhydrochloride	3223-07-2	1g	$522	2021-12-16	Buy

Product number	Packaging	Price	Buy
Y0001158	110 mg	$164	Buy
M216901	100mg	$105	Buy
FM61588	250mg	$125	Buy
API0005250	5MG	$502.94	Buy
4301CR	1g	$522	Buy

4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

Melphalan Hydrochloride is used in combined intravitreal chemotherapy with topotecan hydrochloride for viable vitreous seeding from retinoblastoma. Also, it is an anti-cancer chemotherapy drug.

Safety Profile

Deadly poison by intravenousroute. Human systemic effects by ingestion: nausea andvomiting. Questionable carcinogen with experimentalcarcinogenic data. When heated to decomposition it emitsvery toxic fumes of Cl-, NOx, and HCl.

4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE Suppliers

Global( 135)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Xi'an Yutbon Pharmaceutical Technology Co., Ltd	029-81140587 +8618717328141	sales@yutbon.com	China	454	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-18789408387	1057@dideu.com	China	3944	58
Hebei Mujin Biotechnology Co.,Ltd	+86-13288715578	sales@hbmojin.com	China	12648	58
Changzhou Rokechem Technology Co., Ltd.	18758118018	sales001@rokechem.com	China	255	58
Wuhan JiyunZen Tech Co., Ltd.	+86-18062099985	Amyjiyunzen@yeah.net	China	663	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21622	55
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49733	58

Supplier	Advantage
Xi'an Yutbon Pharmaceutical Technology Co., Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Changzhou Rokechem Technology Co., Ltd.	58
Wuhan JiyunZen Tech Co., Ltd.	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Hubei Jusheng Technology Co.,Ltd.	58
Accela ChemBio Inc.	58
CONIER CHEM AND PHARMA LIMITED	58

An Introduction to Melphalan and Its Mechanism of Carcinogenesis
Melphalan is an alkylating antineoplastic agent used for high-dose conditioning prior to hematopoietic stem cell transplant in....
Feb 3，2023

View Lastest Price from 4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-08-05	MELPHALAN HCL 3223-07-2	US $5.00-0.50 / KG	1KG	99% hplc	500TONS	Wuhan JiyunZen Tech Co., Ltd.
2025-08-01	Melphalan hydrochloride 3223-07-2	US $0.00 / KG	1KG	98.0%	100kg	WUHAN FORTUNA CHEMICAL CO., LTD
2025-07-07	4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE 3223-07-2	US $0.00 / kg	1kg	99.8%	1000tons	Hebei Mujin Biotechnology Co.,Ltd

MELPHALAN HCL
3223-07-2
US $5.00-0.50 / KG
99% hplc
Wuhan JiyunZen Tech Co., Ltd.

Melphalan hydrochloride
3223-07-2
US $0.00 / KG
98.0%
WUHAN FORTUNA CHEMICAL CO., LTD

4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE
3223-07-2
US $0.00 / kg
99.8%
Hebei Mujin Biotechnology Co.,Ltd

3223-07-2(4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE)Related Search:

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4-Amino-L-phenylalanine hydrochloride 4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE Bis(2-chloroethyl)amine hydrochloride 4-Amino-L-phenylalanine 2-(4-AMINOPHENYL)ETHYL AMINE 2HCL

N-Chloroethyl-N-ethylaniline Melphalan Chlormethine

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l-3-(p-(bis(2-chloroethyl)amino)phenyl)alaninemonohydrochloride l-phenylalaninemustardhydrochloride l-sarcolysinehydrochloride 4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE MELPHALAN HCL MELPHALAN HYDROCHLORIDE phenylalaninemustardhydrochloride Phenylalanine, 4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1) 2-AMINO-3-(4-(BIS(2-CHLOROETHYL)AMINO)PHENYL)PROPANOIC ACID HYDROCHLORIDE (MELPHALAN HYDROCHLORIDE) (S)-3-[4-[Bis(2-chloroethyl)amino]phenyl]alanine hydrochloride Melphalan Hydrochloride (100 mg) (International Restricted Sales Item) Melphalan for system suitability 4-[Bis(2-chloroethyl)amino]-L-phenylalanine hydrochloride 4-[Bis(2-chloroethyl)amino]-L-phenylalanine hydrochloride (1:1) 3-(p-(bis(2-chloroethyl)amino)phenyl)-,monohydrochloride,l-alanin 3-(p-(bis(2-chloroethyl)amino)phenyl)-l-alaninhydrochloride 4-(bis(2-chloroethyl)amino)-l-phenylalaninmonohydrochloride alaninenitrogenmustardhydrochloride Melphalan hydrochloride CRS 4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE USP/EP/BP Melphalan Hydrochloride (Y0001158) CAS 3223-07-2 4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE Melphalan Hydrochloride (1379300) EVOMELA Melphalan HCl API CB 3025 hydrochloride 3223-07-2 C13H18Cl2N2O2HCl C13H18ClN2O2HCl