ChemicalBook >> CAS DataBase List >>PMPA(NAALADaseinhibitor)
PMPA(NAALADaseinhibitor)
- CAS No.
- 173039-10-6
- Chemical Name:
- PMPA(NAALADaseinhibitor)
- Synonyms
- 2-PMPA;CS-2454;NAALADASEINHIBITOR;PMPA(NAALADaseinhibitor);2-PMPA(NAALADaseinhibitor);Pentanedioic acid, 2-(phosphonomethyl)-;2-(Phosphonomethyl)pentane-1,5-dioicacid;2-(PHOSPHONOMETHYL)PENTANEDIOIC ACID (PMPA);inhibit,Inhibitor,2PMPA,Carboxypeptidase,2-PMPA,2 PMPA
- CBNumber:
- CB91075110
- Molecular Formula:
- C6H11O7P
- Molecular Weight:
- 226.12
- MDL Number:
- MFCD00940167
- MOL File:
- 173039-10-6.mol
- MSDS File:
- SDS
Last updated:2023-09-04 16:42:00
| Boiling point | 538.8±60.0 °C(Predicted) |
|---|---|
| Density | 1.658±0.06 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | Soluble to 100 mM in sterile |
| pka | 2.06±0.10(Predicted) |
| form | powder |
| color | white to beige |
| Water Solubility | Soluble to 100 mM in water |
| FDA UNII | XH88WJG9LJ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P305+P351+P338 | |||||||||
| RTECS | SA0454800 | |||||||||
| NFPA 704 |
|
PMPA(NAALADaseinhibitor) price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1612 | 2-PMPA ≥98% (HPLC) | 173039-10-6 | 5MG | $117 | 2023-06-20 | Buy |
| Sigma-Aldrich | SML1612 | 2-PMPA ≥98% (HPLC) | 173039-10-6 | 25MG | $478 | 2023-06-20 | Buy |
| Cayman Chemical | 21916 | 2-(Phosphonomethyl)-pentanedioic Acid ≥95% | 173039-10-6 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 21916 | 2-(Phosphonomethyl)-pentanedioic Acid ≥95% | 173039-10-6 | 5mg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 21916 | 2-(Phosphonomethyl)-pentanedioic Acid ≥95% | 173039-10-6 | 10mg | $139 | 2024-03-01 | Buy |
PMPA(NAALADaseinhibitor) Chemical Properties,Uses,Production
Uses
2-(Phosphonomethyl)pentanedioic Acid is a selective glutamate carboxypeptidase 2 (GCP-II) inhibitor, the enzyme which catabolizes the abundant neuropeptide N-acetyl-aspartyl-glutamate (NAAG) to N-acetylaspartate (NAA) and glutamate. A posiible target in the treatment of multiple sclerosis and Schizophrenia.
Biological Activity
Highly potent and selective inhibitor of? glutamate carboxypeptidase 2 (GCP II/N-acetylated α -linked dipeptidase/NAALADase) with a K i value of 275 pM. Neuroprotective; protects against glutamate-mediated motor neuron degeneration and reduces volume of injury following middle cerebral artery occlusion (MCAO).
Biochem/physiol Actions
2-PMPA is a potent and selective inhibitor of Glutamate carboxypeptidase II (GCPII).
storage
Desiccate at RT
PMPA(NAALADaseinhibitor) Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 73)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9923 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
173039-10-6(PMPA(NAALADaseinhibitor))Related Search:
PMPA(NAALADaseinhibitor)
2-(Phosphonomethyl)pentane-1,5-dioicacid
2-PMPA
CS-2454
2-PMPA(NAALADaseinhibitor)
NAALADASEINHIBITOR
Pentanedioic acid, 2-(phosphonomethyl)-
2-(PHOSPHONOMETHYL)PENTANEDIOIC ACID (PMPA)
inhibit,Inhibitor,2PMPA,Carboxypeptidase,2-PMPA,2 PMPA
173039-10-6