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3-Fluoro-4-nitrobenzoic acid

CAS No.
403-21-4
Chemical Name:
3-Fluoro-4-nitrobenzoic acid
Synonyms
BUTTPARK 32\01-75;3-Fluoro-4-nitrobenzoic;uoro-4-nitrobenzoic Acid;3-FLUORO-4-NITROBENZONICACID;3-FLUORO-4-NITROBENZOIC ACID;3-FLUORO-4-NITROBENZOIC CAID;3-Fluoro-4-nitrobenzoicacid95%;3-Fluoro-4-nitrobenzoicacid99%;4-Carboxy-2-fluoronitrobenzene;3-Fluoro-4-nitrobenzoicAcid>
CBNumber:
CB9155507
Molecular Formula:
C7H4FNO4
Molecular Weight:
185.11
MDL Number:
MFCD01862092
MOL File:
403-21-4.mol
MSDS File:
SDS
Last updated:2023-07-26 16:38:48

3-Fluoro-4-nitrobenzoic acid Properties

Melting point 174-175°C
Boiling point 372.8±27.0 °C(Predicted)
Density 1.568±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to crystal
pka 3.08±0.10(Predicted)
color White to Light yellow to Green
InChI InChI=1S/C7H4FNO4/c8-5-3-4(7(10)11)1-2-6(5)9(12)13/h1-3H,(H,10,11)
InChIKey WVZBIQSKLXJFNX-UHFFFAOYSA-N
SMILES C(O)(=O)C1=CC=C([N+]([O-])=O)C(F)=C1
CAS DataBase Reference 403-21-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-37/38-36-22
Safety Statements  26-36/37/39-37
HazardClass  IRRITANT
HS Code  29163990
NFPA 704
0
2 0

3-Fluoro-4-nitrobenzoic acid price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical F0670 3-Fluoro-4-nitrobenzoic Acid >98.0%(GC)(T) 403-21-4 5g $34 2024-03-01 Buy
TCI Chemical F0670 3-Fluoro-4-nitrobenzoic Acid >98.0%(GC)(T) 403-21-4 25g $135 2024-03-01 Buy
Alfa Aesar H26168 3-Fluoro-4-nitrobenzoic acid, 98+% 403-21-4 1g $165.65 2024-03-01 Buy
Alfa Aesar H26168 3-Fluoro-4-nitrobenzoic acid, 98+% 403-21-4 5g $504.65 2024-03-01 Buy
TRC F595033 3-Fluoro-4-nitrobenzoic Acid 403-21-4 250mg $55 2021-12-16 Buy
Product number Packaging Price Buy
F0670 5g $34 Buy
F0670 25g $135 Buy
H26168 1g $165.65 Buy
H26168 5g $504.65 Buy
F595033 250mg $55 Buy

3-Fluoro-4-nitrobenzoic acid Chemical Properties,Uses,Production

Uses

3-Fluoro-4-nitrobenzoic Acid is used in the synthesis of ABT-072, a non-nucleoside HCV NS5B polymerase inhibitor.

Synthesis

To a solution of 3-fluoro-4-nitrobenzyl alcohol (2.97 g) in acetone (60 ml) was added Jones reagent (13 ml), prepared from chromic acid (26.7 g) and sulfuric acid (23 ml) in water (100 ml), dropwise at 0°C. The mixture was stirred on a ice-bath for 0.5 h and quenched with isopropanol (20 ml) to be concentrated in vacuo. The residue was dissolved in ethyl acetate (30 ml) and washed with water (30 ml X 3), and brine (30 ml X 1), successively. The organic layer was dried over sodium sulfate and concentrated in vacuo to obtain a yellow solid, that was triturated with hexane. 3-fluoro-4-nitrobenzoic acid as a pale yellow solid (2.94 g, 92%).
3-Fluoro-4-nitrobenzoic acid synthesis

446-34-4
403-21-4
Synthesis of 3-Fluoro-4-nitrobenzoic acid from 3-Fluoro-4-nitrotoluene
Global( 297)Suppliers
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Aceschem Inc.
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Baynoe Chem (Suzhou) Co., Ltd.
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Fluoropharm Co., Ltd.
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Nanjing Dolon Biotechnology Co.,Ltd.
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Accela ChemBio Inc.
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Changzhou Ditong Chemical Co.,Ltd
+86-0519-88299272 info@edengenechem.com China 2169 58

View Lastest Price from 3-Fluoro-4-nitrobenzoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Fluoro-4-nitrobenzoic acid pictures 2023-09-06 3-Fluoro-4-nitrobenzoic acid
403-21-4
US $30.00-10.00 / KG 50KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
3-Fluoro-4-nitrobenzoic acid pictures 2022-10-27 3-Fluoro-4-nitrobenzoic acid
403-21-4
US $30.00 / kg 1kg 99% 100 tons Hebei Duling International Trade Co. LTD
3-Fluoro-4-nitrobenzoic acid pictures 2021-07-13 3-Fluoro-4-nitrobenzoic acid
403-21-4
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
3-FLUORO-4-NITROBENZENECARBOXYLIC ACID 3-FLUORO-4-NITROBENZOIC ACID BUTTPARK 32\01-75 3-FLUORO-4-NITROBENZONICACID 3-Fluoro-4-nitrobenzoicacid95% 3-Fluoro-4-nitrobenzoic 3-Fluoro-4-nitrobenzoic acid 99% 3-Fluoro-4-nitrobenzoicacid99% 3-Fluoro-4-nitrobenzoic acid, 98+% 3- fluorine-4-Nitrobenzoic Acid 4-Carboxy-2-fluoronitrobenzene 3-Fluoride-4-Nitro Benzoic Acids 3-Fluoro-4-nitrobenzoicAcid> Benzoic acid, 3-fluoro-4-nitro- uoro-4-nitrobenzoic Acid 3-FLUORO-4-NITROBENZOIC CAID 403-21-4 403-21-1 Carboxylic Acids Phenyls & Phenyl-Het Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts Miscellaneous blocks Carboxes FluoroCompounds NitroCompounds Acids and Derivatives