ChemicalBook >> CAS DataBase List >>Cyclopentanone, 2,5-bis(2-thienylMethylene)-, (E,E)-
Cyclopentanone, 2,5-bis(2-thienylMethylene)-, (E,E)-
- CAS No.
- 176957-55-4
- Chemical Name:
- Cyclopentanone, 2,5-bis(2-thienylMethylene)-, (E,E)-
- Synonyms
- CS-1839;CCT007093;CCTOO7093;CCT-007093; CCT 007093; CCT007093;2,5-Bis(2-thienylmethylene)-cyclopentanone;(2E,5E)-2,5-Bis(2-thienylmethylene)cyclopentanone;2,5-bis(2-thienylMethylene)-, (E,E)-Cyclopentanone;Cyclopentanone, 2,5-bis(2-thienylMethylene)-, (E,E)-;(2E,5E)-2,5-Bis(thiophen-2-ylmethylene)cyclopentanone;Cyclopentanone, 2,5-bis(2-thienylmethylene)-, (2E,5E)-
- CBNumber:
- CB92682247
- Molecular Formula:
- C15H12OS2
- Molecular Weight:
- 272.39
- MDL Number:
- MFCD00121546
- MOL File:
- 176957-55-4.mol
- MSDS File:
- SDS
Last updated:2023-06-08 09:02:45
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
Cyclopentanone, 2,5-bis(2-thienylMethylene)-, (E,E)- price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C9369 | CCT007093 ≥98% (HPLC), powder, yellow | 176957-55-4 | 5mg | $103 | 2024-03-01 | Buy |
| Sigma-Aldrich | C9369 | CCT007093 ≥98% (HPLC), powder, yellow | 176957-55-4 | 25mg | $393 | 2024-03-01 | Buy |
| Alfa Aesar | J64165 | PPM1D Phosphatase Inhibitor | 176957-55-4 | 50mg | $399 | 2021-12-16 | Buy |
| Alfa Aesar | J64165 | PPM1D Phosphatase Inhibitor | 176957-55-4 | 10mg | $104 | 2021-12-16 | Buy |
| Cayman Chemical | 19992 | CCT007093 ≥98% | 176957-55-4 | 1mg | $32 | 2024-03-01 | Buy |
Cyclopentanone, 2,5-bis(2-thienylMethylene)-, (E,E)- Chemical Properties,Uses,Production
Uses
Acts as a PPM1D inhibitor
Biological Activity
cct007093 is a small-molecule chemical inhibitor of ppm1d with ic50 value of 8.4μm [1].cct007093 is a thienylidene cyclopentanone and shows a potent inhibition of ppm1d in the in vitro assay when using the recombinant phospho-p38 as a substrate. in cellular assay, cct007093 shows specificity for mcf-7 cells over hela cells. it reduces 40% viability of the cells after 2 days. it is found that the cell death induced by cct007093 is dependent on p38 kinase activity. cct007093 mimics the effect of ppm1d rnai in activating p38 kinase. it induces p38 phosphorylation at 4 h post-exposure in mcf-7 cells and the loss of viability can be rescued by sb203580, the specific p38 inhibitor [1].
target
WIP1
References
[1] rayter s, elliott r, travers j, rowlands mg, richardson tb, boxall k, jones k, linardopoulos s, workman p, aherne w, lord cj, ashworth a. a chemical inhibitor of ppm1d that selectively kills cells overexpressing ppm1d. oncogene. 2008 feb 14;27(8):1036-44.
Cyclopentanone, 2,5-bis(2-thienylMethylene)-, (E,E)- Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 92)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9634 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
View Lastest Price from Cyclopentanone, 2,5-bis(2-thienylMethylene)-, (E,E)- manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-14 | Cyclopentanone, 2,5-bis(2-thienylMethylene)-, (E,E)-
176957-55-4
|
US $9.80 / KG | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- Cyclopentanone, 2,5-bis(2-thienylMethylene)-, (E,E)-
176957-55-4
- US $9.80 / KG
- ≥99%
- Career Henan Chemical Co
176957-55-4(Cyclopentanone, 2,5-bis(2-thienylMethylene)-, (E,E)-)Related Search:
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Inhibitors