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Methoxy-X04

CAS No.
863918-78-9
Chemical Name:
Methoxy-X04
Synonyms
Methoxy-X04;MethoxyX04,Methoxy X04,Methoxy-X-04;4,4'-[(2-methoxy-1,4-phenylene)di-(1E)-2,1-ethenediyl]bisphenol;4,4'-((1E,1'E)-(2-Methoxy-1,4-phenylene)bis(ethene-2,1-diyl))diphenol;4,4'-((1E,1'E)-(2-Methoxy-1,4-phenylene)bis(ethene-2,1-diyl))diphenol;Phenol, 4,4'-[(2-methoxy-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis- (9CI)
CBNumber:
CB93067560
Molecular Formula:
C23H20O3
Molecular Weight:
344.4031
MDL Number:
MFCD25563254
MOL File:
863918-78-9.mol
MSDS File:
SDS
Last updated:2023-09-04 15:51:00

Methoxy-X04 Properties

Boiling point 554.2±29.0 °C(Predicted)
Density 1.244±0.06 g/cm3(Predicted)
storage temp. Store at -20°C,protect from light
solubility Soluble in DMSO
form crystalline solid
pka 9.98±0.26(Predicted)
color Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
NFPA 704
0
2 0

Methoxy-X04 price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 20476 Methoxy-X04 ≥95% 863918-78-9 1mg $32 2024-03-01 Buy
Cayman Chemical 20476 Methoxy-X04 ≥95% 863918-78-9 5mg $109 2024-03-01 Buy
Cayman Chemical 20476 Methoxy-X04 ≥95% 863918-78-9 10mg $169 2024-03-01 Buy
Tocris 4920 Methoxy-X04 ≥98%(HPLC) 863918-78-9 10 $173 2021-12-16 Buy
Tocris 4920 Methoxy-X04 ≥98%(HPLC) 863918-78-9 50 $724 2021-12-16 Buy
Product number Packaging Price Buy
20476 1mg $32 Buy
20476 5mg $109 Buy
20476 10mg $169 Buy
4920 10 $173 Buy
4920 50 $724 Buy

Methoxy-X04 Chemical Properties,Uses,Production

Description

Methoxy-X04 is a brain-permeable fluorescent probe for amyloid-β (Aβ) to detect and quantify plaques, tangles, and cerebrovascular amyloid. It displays high in vitro binding affinity (Ki = 26.8 nM) for fibrillar β-sheet deposits and is used to image Aβ plaques in the brains of living APP/PS1 mice, a transgenic model of familial Alzheimer''s disease. For in vivo imaging, APP/PS1 mice were injected with methoxy-X04 at a dose of 10 mg/kg, i.p., 24 hours prior to two-photon imaging. Methoxy-X04 displays an excitation peak at 750 nm with emission between 460 and 500 nm.

Uses

Methoxy-X04 is a small molecule Aβ-binding agent, which exhibits anti-amyloid effects.

storage

+4°C. Protect from light.

Methoxy-X04 Preparation Products And Raw materials

Raw materials

Preparation Products

Methoxy-X04 Suppliers

Global( 64)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131980 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4182 55
Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921 sales@pharmacodia.com China 2317 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9708 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3500 55
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720 chaolaichem@foxmail.com China 9242 58
Zhengzhou Acme Chemical Co., Ltd. 0371-0371-55629727 13323845623 2885676761@qq.com China 9859 58

Methoxy-X04 Spectrum

Methoxy-X04 4,4'-[(2-methoxy-1,4-phenylene)di-(1E)-2,1-ethenediyl]bisphenol MethoxyX04,Methoxy X04,Methoxy-X-04 Phenol, 4,4'-[(2-methoxy-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis- (9CI) 4,4'-((1E,1'E)-(2-Methoxy-1,4-phenylene)bis(ethene-2,1-diyl))diphenol 4,4'-((1E,1'E)-(2-Methoxy-1,4-phenylene)bis(ethene-2,1-diyl))diphenol 863918-78-9