ChemicalBook >> CAS DataBase List >>Toluene-4-sulfonic acid 4-tert-butoxycarbonylamino-butyl ester
Toluene-4-sulfonic acid 4-tert-butoxycarbonylamino-butyl ester
- CAS No.
- 180851-50-7
- Chemical Name:
- Toluene-4-sulfonic acid 4-tert-butoxycarbonylamino-butyl ester
- Synonyms
- Tos-O-C4-NH-Boc;Toluene-4-sulfonic acid 4-bocamin;Toluene-4-sulfonic acid 4-bocamino-butyl ester, 97%;4-((tert-Butoxycarbonyl)amino)butyl 4-methylbenzenesulfonate;Toluene-4-sulfonic acid 4-tert-butoxycarbonylamino-butyl ester;Carbamic acid, N-[4-[[(4-methylphenyl)sulfonyl]oxy]butyl]-, 1,1-dimethylethyl ester
- CBNumber:
- CB93400271
- Molecular Formula:
- C16H25NO5S
- Molecular Weight:
- 343.44
- MDL Number:
- MFCD18839142
- MOL File:
- 180851-50-7.mol
- MSDS File:
- SDS
Last updated:2023-06-03 08:28:36
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Toluene-4-sulfonic acid 4-tert-butoxycarbonylamino-butyl ester Chemical Properties,Uses,Production
Biological Activity
Tos-O-C4-NH-Boc is an alkyl ether-based PROTAC linker can be used in the synthesis of PROTACs, such as BSJ-03-204 [1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Targ. J Med Chem. 2019 Aug 21.
Synthesis of Toluene-4-sulfonic acid 4-tert-butoxycarbonylamino-butyl ester from 4-(tert-ButoxycarbonylaMino)-1-butanol and Tosyl chloride
Toluene-4-sulfonic acid 4-tert-butoxycarbonylamino-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Toluene-4-sulfonic acid 4-tert-butoxycarbonylamino-butyl ester Suppliers
Global( 16)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
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| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
| Jiangsu aikang biomedical research and development co., LTD | 025-66110311 13155353615 | qzhang@aikonchem.com | China | 15527 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
| Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49323 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223 | psaitong@jm-bio.com | China | 29834 | 58 |
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| CHO Chemical Materials Chang Zhou CO., LTD | 15995034354 | purchase@chochem.cn | China | 2707 | 58 |
Toluene-4-sulfonic acid 4-tert-butoxycarbonylamino-butyl ester
Toluene-4-sulfonic acid 4-bocamino-butyl ester, 97%
Carbamic acid, N-[4-[[(4-methylphenyl)sulfonyl]oxy]butyl]-, 1,1-dimethylethyl ester
Tos-O-C4-NH-Boc
Toluene-4-sulfonic acid 4-bocamin
4-((tert-Butoxycarbonyl)amino)butyl 4-methylbenzenesulfonate
180851-50-7