N-NITROSO-L-PROLINE
- CAS No.
- 7519-36-0
- Chemical Name:
- N-NITROSO-L-PROLINE
- Synonyms
- NPRO;no-pro;Nsc109545;nitrosoproline;1-Nitrosoproline;N-NITROSO-PROLINE;1-nitroso-l-proline;N-NITROSO-L-PROLINE;L-Proline, nitroso-;L-Proline, 1-nitroso-
- CBNumber:
- CB9489314
- Molecular Formula:
- C5H8N2O3
- Molecular Weight:
- 144.13
- MDL Number:
- MFCD01698777
- MOL File:
- 7519-36-0.mol
Melting point | 108-109°C |
---|---|
Boiling point | 262.71°C (rough estimate) |
Density | 1.4054 (rough estimate) |
refractive index | 1.4472 (estimate) |
storage temp. | -20°C Freezer |
solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Sparingly) |
pka | 3.23±0.20(Predicted) |
form | Solid |
color | Pale Yellow to Brown |
FDA UNII | F8MI03SGY0 |
IARC | 3 (Vol. 17, Sup 7) 1987 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08,GHS07 |
---|---|
Signal word | Danger |
Hazard statements | H319-H302-H334-H351-H341-H315-H312-H335 |
Precautionary statements | P261-P285-P304+P341-P342+P311-P501-P201-P202-P281-P308+P313-P405-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P280-P302+P352-P312-P322-P363-P501-P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P312-P330-P501 |
Toxicity | LD50 ipr-mus: 203 mg/kg JMCMAR 16,583,73 |
N-NITROSO-L-PROLINE price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Usbiological | 285292 | N-Nitroso-L-proline | 7519-36-0 | 5mg | $403 | 2021-12-16 | Buy |
TRC | N545450 | N-Nitroso-L-proline | 7519-36-0 | 50mg | $685 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | AAA0000646 | N-NITROSO-L-PROLINE 95.00% | 7519-36-0 | 5MG | $738.1 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 12682 | N-Nitroso-L-proline | 7519-36-0 | 10mg | $860 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | AAA0000646 | N-NITROSO-L-PROLINE 95.00% | 7519-36-0 | 100MG | $1593.9 | 2021-12-16 | Buy |
N-NITROSO-L-PROLINE Chemical Properties,Uses,Production
Chemical Properties
Colourless Plates
Uses
A nitrosoamino acid with oncogenicity. The LD50 of a single ip dose given to Swiss-Webster mice is 203 +/- 22 mg / kg
Uses
A nitrosoamino acid with oncogenic activity. The LD50 of a single ip dose given to Swiss-Webster mice is 203 +/- 22 mg / kg.
Definition
ChEBI: N-Nitrosoproline is a L-proline derivative.
Production Methods
There is no indication that nitrosoproline was made commercially. It has been reported in cured meats (e.g., bacon) at concentrations of 340–440 μg/kg. Both higher and lower levels in several cured products have been reported by several authors.
Safety Profile
Poison by intraperitoneal route.Questionable carcinogen with experimental tumorigenicdata. Many nitroso compounds are carcinogens. Whenheated to decomposition it emits toxic fumes of NOx. Seealso NITROSO COMPOUNDS.
Carcinogenicity
Mice were given 0.1% NPRO in drinking water for 26 weeks, and no more lung adenomas were seen than in untreated controls at 38 weeks, showing a lack of carcinogenicity. In rats, higher doses (0.145%) in drinking water for 2 years showed no tumors that were not seen in untreated controls (174). IARC classified NPRO as not classifiable as to carcinogenicity to humans (Group 3).
N-NITROSO-L-PROLINE Preparation Products And Raw materials
Raw materials
Preparation Products
N-NITROSO-L-PROLINE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3878 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29823 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52861 | 58 |
sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50003 | 58 |
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd | 18162595016; 18162595016 | 3287908757@qq.com | China | 9117 | 58 |
Guangzhou Younan Technology Co., Ltd | 020-020-82000279 18988968278 | sales@ubiochem.com | China | 4297 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
View Lastest Price from N-NITROSO-L-PROLINE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-08-15 | N-NITROSO-L-PROLINE
7519-36-0
|
US $0.10 / KG | 1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd | ||
2020-01-09 | N-Boc-trans-4-amino-L-proline methyl ester hydrochloride
7519-36-0
|
US $1.00 / g | 1g | ≥98% | g/kg/Ton | Career Henan Chemical Co |
- N-NITROSO-L-PROLINE
7519-36-0
- US $0.10 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
- N-Boc-trans-4-amino-L-proline methyl ester hydrochloride
7519-36-0
- US $1.00 / g
- ≥98%
- Career Henan Chemical Co