Endosidin 2
Endosidin 2 物理性質
- 比重(密度) :
- 1.67±0.1 g/cm3(Predicted)
- 貯蔵温度 :
- 2-8°C
- 溶解性:
- DMSO (40mg/ml以上)、DMF (最大35mg/ml) またはエタノール (最大10mg/ml) に可溶
- 外見 :
- 粉
- 酸解離定数(Pka):
- 7.75±0.36(Predicted)
- 色:
- 白からベージュ
- 安定性：:
- 購入日から2年間安定です。 DMSO、DMF、またはエタノール中のこの溶液は、-20°C で 1 か月間保存できます。
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
Endosidin 2 価格
もっと(2)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
Sigma-Aldrich Japan
|
SML1681 |
≥98% (HPLC)
Endosidin2 ≥98% (HPLC) |
1839524-44-5 |
5mg |
￥21800 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
SML1681 |
≥98% (HPLC)
Endosidin2 ≥98% (HPLC) |
1839524-44-5 |
25mg |
￥87500 |
2024-03-01 |
購入 |
Endosidin 2 化学特性,用途語,生産方法
使用
Endosidin 2 binds to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex, resulting in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking. A valuable tool for exocytosis studies.
Biochem/physiol Actions
Endosidin2 is a cell-permeable benzylidene-benzohydrazide based compound that binds to the exocyst component of 70 kDa (EXO70) subunit of exocyst complex (Kd?= 253 μM for interaction with EXO70A1) and reduces exocytosis and endosomal recycling in plant and mammalian cells. Displays good aqueous stability. Endosidin2 has shown to disrupt the trafficking of proteins between the plasma membrane and endosome, which leads to enhanced trafficking to the vacuole for degradation. It is reported to inhibit the recycling of endocytosed transferrin to plasma membrane in HeLa cells, and can target multiple isoforms of EXO70 in mammals, resulting in misregulation of exocytosis.
Endosidin 2 上流と下流の製品情報
原材料
準備製品
Endosidin 2 生産企業
Global( 16)Suppliers
1839524-44-5()キーワード:
- 1839524-44-5
- Endosidin 2
- Endosidin-2
(ES-2)
- Benzoic acid, 3-fluoro-, (2E)-2-[(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]hydrazide
- 3-fluoro-benzoicacid,(2E)-2-[(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]hydrazide