ChemicalBook
Chinese english Germany Korea

キサンタンガム

キサンタンガム 化学構造式
11138-66-2
CAS番号.
11138-66-2
化学名:
キサンタンガム
别名:
キサンタンガム;キサンタンゴム;キサンタンガム FROM XANTHOMONAS CAMPESTRIS
英語化学名:
Xanthan gum
英語别名:
XANTHAN;XANTHAM;Tarazine;Keltrol F;Xanthan g;XANTHATEGUM;GUM XANTHAN;XANTHAN GUM;RHODOPOL 23;Xanthane gum
CBNumber:
CB3735028
化学式:
C8H14Cl2N2O2
分子量:
241.11496
MOL File:
11138-66-2.mol

キサンタンガム 物理性質

融点 :
64.43 °C
溶解性:
Soluble in water giving a highly viscous solution, practically insoluble in organic solvents.
Merck :
14,10057
安定性::
Stable. Combustible. Incompatible with strong oxidizing agents.
CAS データベース:
11138-66-2(CAS DataBase Reference)
EPAの化学物質情報:
Xanthan gum (11138-66-2)

安全性情報

Sフレーズ  24/25
WGK Germany  1
HSコード  32139000
化審法 届出不要化学物質

キサンタンガム 価格 もっと(13)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01MPB02960021 キサンタンガム
Xanthan Gum
11138-66-2 100g ¥10200 2021-03-23 購入
富士フイルム和光純薬株式会社(wako) W01MPB02960021 キサンタンガム
Xanthan Gum
11138-66-2 500g ¥26300 2021-03-23 購入
東京化成工業 X0048 キサンタンガム
Xanthan Gum
11138-66-2 25g ¥2900 2021-03-23 購入
東京化成工業 X0048 キサンタンガム
Xanthan Gum
11138-66-2 100g ¥6400 2021-03-23 購入
Sigma-Aldrich Japan 43708
Xanthan from Xanthomonas campestris
11138-66-2 50g ¥6800 2018-12-25 購入

キサンタンガム MSDS


Xanthan gum

キサンタンガム 化学特性,用途語,生産方法

外観

白色~うすい赤色~緑色粉末~結晶

定義

本品は、炭水化物を Xanthomonas campestris で醗酵して得られる多糖類である。

解説

多糖類の一種。砂糖溶液やでんぷん中で細菌の一種が産生。水溶性の天然糊料であり、増粘安定剤、乳化剤、化粧水の保水剤として用いられる。
小学館 デジタル大辞泉について 情報 | 凡例

化粧品の成分用途

結合剤、皮膚コンディショニング剤、親水性増粘剤、乳化安定剤、乳化剤

化学的特性

viscosity of 1% solution 1,200-1,600 mPas

化学的特性

Xanthan gum occurs as a cream- or white-colored, odorless, freeflowing, fine powder.

使用

Xanthan Gum is a gum obtained by microbial fermentation from the xanthomonas campestris organism. it is very stable to viscosity change over varying temperatures, ph, and salt concentrations. it is also very pseudoplastic which results in a decrease in viscosity with increasing shear. it reacts synergistically with guar gum and tara gum to provide an increase in viscosity and with carob gum to provide an increase in viscosity or gel formation. it is used in salad dressings, sauces, desserts, baked goods, and beverages at 0.05–0.50%.

使用

In foods, pharmaceuticals, and cosmetics as stabilizer and thickening agent. For rheology control in water-based systems. In oil and gas drilling and completion fluids.

使用

xanthan gum (corn starch gum) serves as a texturizer, carrier agent, and gelling agent in cosmetic preparations. It also stabilizes and thickens formulations. This gum is produced through a fermentation of carbohydrate and Xanthomonas campestris.

調製方法

Xanthan gum is a polysaccharide produced by a pure-culture aerobic fermentation of a carbohydrate with Xanthomonas campestris. The polysaccharide is then purified by recovery with propan-2-ol, dried, and milled.

brand name

Rhodigel (Vanderbilt).

一般的な説明

As xanthan is a polysaccharide used in many applications such as a food additive, enzyme substrate or rheology modifier, it is useful to have a xanthan standard with a clearly defined narrow molecular weight distribution. Xanthan is produced by fermentation from Xanthomonas campestris.

応用例(製薬)

Xanthan gum is widely used in oral and topical pharmaceutical formulations, cosmetics, and foods as a suspending and stabilizing agent. It is also used as a thickening and emulsifying agent. It is nontoxic, compatible with most other pharmaceutical ingredients, and has good stability and viscosity properties over a wide pH and temperature range. Xanthan gum gels show pseudoplastic behavior, the shear thinning being directly proportional to the shear rate. The viscosity returns to normal immediately on release of shear stress.
Xanthan gum has been used as a suspending agent for conventional, dry and sustained-release suspensions. When xanthan gum is mixed with certain inorganic suspending agents, such as magnesium aluminum silicate, or organic gums, synergistic rheological effects occur. In general, mixtures of xanthan gum and magnesium aluminum silicate in ratios between 1 : 2 and 1 : 9 produce the optimum properties. Similarly, optimum synergistic effects are obtained with xanthan gum : guar gum ratios between 3 : 7 and 1 : 9.
Although primarily used as a suspending agent, xanthan gum has also been used to prepare sustained-release matrix tablets. Controlled-release tablets of diltiazem hydrochloride prepared using xanthan gum have been reported to sustain the drug release in a predictable manner, and the drug release profiles of these tablets were not affected by pH and agitation rate. Xanthan gum has also been used to produce directly compressed matrices that display a high degree of swelling due to water uptake, and a small amount of erosion due to polymer relaxation. It has also been used in combination with chitosan, guar gum, galactomannan, and sodium alginate to prepare sustained-release matrix tablets. Xanthan gum has been used as a binder, and in combination with Konjac glucomannan is used as an excipient for controlled colonic drug delivery. Xanthan gum with boswellia (3 : 1) and guar gum (10 : 20) have shown the best release profiles for the colon-specific compression coated systems of 5- fluorouracil for the treatment of colorectal cancer. Xanthan gum has also been used with guar gum for the development of a floating drug delivery system.It has also has derivatized to sodium carboxymethyl xanthan gum and crosslinked with aluminum ions to prepare microparticles, as a carrier for protein delivery. Xanthan gum has been incorporated in an ophthalmic liquid dosage form, which interacts with mucin, thereby helping in the prolonged retention of the dosage form in the precorneal area. When added to liquid ophthalmics, xanthan gum delays the release of active substances, increasing the therapeutic activity of the pharmaceutical formulations.
Xanthan gum can be used to increase the bioadhesive strength in vaginal formulations. Xanthan gum alone or with carbopol 974P has been used as a mucoadhesive controlled-release excipient for buccal drug delivery. Modified xanthan films have been used as a matrix system for transdermal delivery of atenolol. Xanthan gum has also been used as a gelling agent for topical formulations incorporating solid lipid nanoparticles of vitamin A or microemulsion of ibuprofen. A combined polymer system consisting of xanthan gum, carboxy methylcellulose and a polyvinyl pyrolidone backboned polymer has been used for relieving the symptoms of xerostomia. Xanthan gum can also be used as an excipient for spray-drying and freeze-drying processes for better results. It has been successfully used alone or in combination with agar for microbial culture media.
Xanthan gum is also used as a hydrocolloid in the food industry, and in cosmetics it has been used as a thickening agent in shampoo. Polyphosphate with xanthum gum in soft drinks is suggested to be effective at reducing erosion of enamel

安全性プロファイル

When heated to decomposition it emits acrid smoke and irritating fumes.

安全性

Xanthan gum is widely used in oral and topical pharmaceutical formulations, cosmetics, and food products, and is generally regarded as nontoxic and nonirritant at the levels employed as a pharmaceutical excipient.
The estimated acceptable daily intake for xanthan gum has been set by the WHO at up to 10 mg/kg body-weight.
No eye or skin irritation has been observed in rabbits and no skin allergy has been observed in guinea pigs following skin exposure. No adverse effects were observed in long term feeding studies with rats (up to 1000 mg/kg/day) and dogs (up to 1000 mg/kg/day). No adverse effects were observed in a three-generation reproduction study with rats (up to 500 mg/kg/day).
LD50 (dog, oral): >20 g/kg
LD50 (rat, oral): >45 g/kg
LD50 (mouse, oral): >1 g/kg
LD50 (mouse, IP): >50 mg/kg
LD50 (mouse, IV): 100–250 mg/kg

貯蔵

Xanthan gum is a stable material. Aqueous solutions are stable over a wide pH range (pH 3–12), although they demonstrate maximum stability at pH 4–10 and temperatures of 10–60°C. Xanthan gum solutions of less than 1% w/v concentration may be adversely affected by higher than ambient temperatures: for example, viscosity is reduced. Xanthan gum provides the same thickening, stabilizing, and suspending properties during long-term storage at elevated temperatures as it does at ambient conditions. In addition, it ensures excellent freeze–thaw stability. Solutions are also stable in the presence of enzymes, salts, acids, and bases. Vanzan NF-ST is especially designed for use in systems containing high salt concentrations as it dissolves directly in salt solutions, and its viscosity is relatively unaffected by high salt levels as compared with general purpose grades.
The bulk material should be stored in a well-closed container in a cool, dry place.

不和合性

Xanthan gum is an anionic material and is not usually compatible with cationic surfactants, polymers, or preservatives, as precipitation occurs. Anionic and amphoteric surfactants at concentrations above 15% w/v cause precipitation of xanthan gum from a solution.
Under highly alkaline conditions, polyvalent metal ions such as calcium cause gelation or precipitation; this may be inhibited by the addition of a glucoheptonate sequestrant. The presence of low levels of borates (<300 ppm) can also cause gelation. This may be avoided by increasing the boron ion concentration or by lowering the pH of a formulation to less than pH 5. The addition of ethylene glycol, sorbitol, or mannitol may also prevent this gelation.
Xanthan gum is compatible with most synthetic and natural viscosity-increasing agents, many strong mineral acids, and up to 30% inorganic salts. If it is to be combined with cellulose derivatives, then xanthan gum free of cellulase should be used to prevent depolymerization of the cellulose derivative. Xanthan gum solutions are stable in the presence of up to 60% water-miscible organic solvents such as acetone, methanol, ethanol, or propan-2- ol. However, above this concentration precipitation or gelation occurs.
The viscosity of xanthan gum solutions is considerably increased, or gelation occurs, in the presence of some materials such as ceratonia, guar gum, and magnesium aluminum silicate. This effect is most pronounced in deionized water and is reduced by the presence of salt. This interaction may be desirable in some instances and can be exploited to reduce the amount of xanthan gum used in a formulation.
Xanthan gum is incompatible with oxidizing agents, some tablet film-coatings, carboxymethylcellulose sodium, dried aluminum hydroxide gel, and some active ingredients such as amitriptyline, tamoxifen, and verapamil.

規制状況(Regulatory Status)

GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral solutions, suspensions, and tablets; rectal and topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

キサンタンガム 上流と下流の製品情報

原材料

準備製品


キサンタンガム 生産企業

Global( 402)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
hdzhl biotechnology co., ltd
86-13032617415
sales@luchibiology.com CHINA 1275 58
Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
02569916489
02569916489 tongyuansales@vip.sina.com CHINA 259 58
Hebei Henghe Import and Export Trading Co. LTD
18032916000 +8618032935937
demi@hbtycoon.com CHINA 453 58
HONG KONG IPURE BIOLOGY CO.,LIMITED
18062405514 86 18062405514
ada@ipurechemical.com CHINA 3475 58
Hebei Yirun Sega Biological Technology Co. Ltd
19932103556 +8619932103556
+8619932103556 linda@yrsjbiotech.com CHINA 1691 58
Wuhan wingroup Pharmaceutical Co., Ltd
0086-18062075862
0086-27-87819568 admin@whwingroup.com CHINA 2499 58
Shijiazhuang Tongyang Import and Export Co., LTD

admin@sjztongyang.com CHINA 995 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com China 9156 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 890 55

11138-66-2(キサンタンガム)キーワード:


  • 11138-66-2
  • GUM XANTHAN
  • GLUCOMANNAN MAYO
  • GALACTOMANNANE
  • XANTHANGUM,FCC
  • XANTHANGUM,NF
  • XANTHATEGUM
  • Xanthan Gummi
  • XANTHAN NF, USP
  • XANTHAN GUM POWDER NF/FCC GRADE
  • NL Baroid XC Polymer
  • XANTHAN FROM XANTHOMONAS CAMPESTRIS
  • Best Price Xanthan gum CAS NO.11138-66-2 Fine Chemicals Supplier
  • Hot sale Xanthan gum food additives supplier
  • competitive price food grade xanthan gum
  • Food Grade Cosmetic Grade XANTHAN GUM price
  • new product CAS 11138-66-2 thickener food grade xanthan gum on sale
  • Xanthane gum
  • Xanthan gum from Xanthomonas campestris,Gum xanthan
  • Keltrol F
  • Polysaccharide B-1459
  • Konjac extract
  • Xanthan guM (xanthan)
  • Thexanthan guM
  • Xantural 180
  • Xanthan Gum Industrial Grade/Oil Grade Dispersant Grade
  • XANTHAN
  • XANTHAN GUM
  • XANTEMPO(TM)
  • xanthangumfromxanthomonascampestris
  • RHODOPOL 23
  • キサンタンガム
  • キサンタンゴム
  • キサンタンガム FROM XANTHOMONAS CAMPESTRIS
Copyright 2017 © ChemicalBook. All rights reserved