メトラゾン
メトラゾン 物理性質
- 融点 :
- 252-254°C
- 沸点 :
- 613.6±65.0 °C(Predicted)
- 比重(密度) :
- 1.2895 (rough estimate)
- 屈折率 :
- 1.6100 (estimate)
- 貯蔵温度 :
- 2-8°C
- 溶解性:
- DMSO：>5mg/mL
- 酸解離定数(Pka):
- pKa 9.7 (Uncertain)
- 外見 :
- 個体
- 色:
- 白い
- 水溶解度 :
- 60.3mg/L(25℃)
- 安定性：:
- DMSO 溶液または水溶液中、-20°C で最大 2 か月間保存できます。
- InChIKey:
- AQCHWTWZEMGIFD-UHFFFAOYSA-N
- CAS データベース:
- 17560-51-9(CAS DataBase Reference)
- NISTの化学物質情報:
- Metolazone(17560-51-9)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01USP1441200 |
メトラゾン
Metolazone |
17560-51-9 |
200mg |
￥91400 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
Y0000702 |
システム適合性用メトラゾン European Pharmacopoeia (EP) Reference Standard
Metolazone for system suitability European Pharmacopoeia (EP) Reference Standard |
17560-51-9 |
y0000702 |
￥28300 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
M1195 |
メトラゾン ≥98% (HPLC), solid
Metolazone ≥98% (HPLC), solid |
17560-51-9 |
5mg |
￥19800 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
M1195 |
メトラゾン ≥98% (HPLC), solid
Metolazone ≥98% (HPLC), solid |
17560-51-9 |
25mg |
￥121000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
1441200 |
メトラゾン United States Pharmacopeia (USP) Reference Standard
Metolazone United States Pharmacopeia (USP) Reference Standard |
17560-51-9 |
200mg |
￥55400 |
2024-03-01 |
購入 |
メトラゾン 化学特性,用途語,生産方法
外観
白色～わずかにうすい黄色, 結晶性粉末～粉末
溶解性
アセトンに可溶、メタノールに難溶、クロロホルム,水に不溶。
用途
薬理研究用。
効能
血圧降下薬, 利尿薬, Na+-Cl-再吸収阻害薬
説明
Metolazone (Item No. 26304) is an analytical reference standard categorized as a diuretic. It has been detected as an adverse analytical finding (AAF) during anti-doping testing. This product is intended for use in analytical forensic applications. This product is also available as a general research tool .
化学的特性
Crystalline Solid
使用
Metolazone acts on the distal tubules, thus increasing excretion of water and sodium,
potassium, and chloride ions. It is used for treating edema caused by cardiac insufficiency
and adrenal irregularities, including nephrotic syndrome.
定義
ChEBI: A quinazoline that consists of 1,2,3,4-tetrahydroquinazolin-4-one bearing additional methyl, 2-tolyl, sulfamyl and chloro substituents at positions 2, 3, 6 and 7 respectively. A quinazoline diuretic, with properties similar to thiazide diuretics.
メトラゾン 上流と下流の製品情報
原材料
準備製品
メトラゾン 生産企業
Global( 168)Suppliers
17560-51-9(メトラゾン)キーワード:
- 17560-51-9
- s720-22
- 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide, SR-720-22, Diulo, Metenix, Mykrox, Oldren,
- 6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo- (9CI)
- 6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl- (8CI)
- Normelan
- Xuret
- 6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro- 2-methyl-3-(2-methylphenyl)-4-oxo-
- METAZOLINE
- 7-CHLORO-2-METHYL-4-OXO-3-O-TOLYL-1,2,3,4-TETRAHYDROQUINAZOLINE-6-SULFONAMIDE
- Metolazone【hypotensive drug】
- Metolazone,7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide
- Metolazone (200 mg)
- OLDREN
- SR-720-22
- METOLAZONE
- METENIX
- 1,2,3,4-tetrahydro-7-chloro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamid
- 2-methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone
- 6-quinazolinesulfonamide,7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylpheny
- 7-CHLORO-1,2,3,4-TETRAHYDRO-2-METHYL-3-(2-METHYLPHENYL)-4-OXO-6-QUINAZOLINESULFONAMIDE
- Metolazone(Zaroxolyn)
- Metozalone
- Metolazone, >=99%
- 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesul
- 7-chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamid
- 7-chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-tolyl-6-quinazolinesulfonamide
- fonamide
- l)-4-oxo-
- metalozone
- microx
- メトラゾン【降圧薬】
- メトラゾン【利尿剤】
- ノルメラン
- 7-クロロ-1,2,3,4-テトラヒドロ-2-メチル-3-(2-メチルフェニル)-4-オキソ-6-キナゾリンスルホンアミド
- メトラゾン
- メトラゾン (JAN)
- 7-クロロ-2-メチル-3-(2-メチルフェニル)-4-オキソ-1,2,3,4-テトラヒドロキナゾリン-6-スルホンアミド
- 降圧薬
- 利尿薬