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モキシデクチン

モキシデクチン 化学構造式
113507-06-5
CAS番号.
113507-06-5
化学名:
モキシデクチン
别名:
モキシデクチン;モキシデクチン標準品
英語化学名:
Moxidectin
英語别名:
Quest;Equest;proheart;Moxdectin;Moxidectin;ProHeart 6;Moxidectin, >=98%;Cydectin, CL 301,423;Vetdectin Oral Drench;23-MethoxiMe-LL-F 28249α
CBNumber:
CB4874771
化学式:
C37H53NO8
分子量:
639.825
MOL File:
113507-06-5.mol

モキシデクチン 物理性質

貯蔵温度 :
2-8°C
外見 :
neat
InChIKey:
YZBLFMPOMVTDJY-LSGXYNIPSA-N
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
主な危険性  T,N
Rフレーズ  25-50
Sフレーズ  45-61-24/25
RIDADR  2588
WGK Germany  3
RTECS 番号 PY5438800
国連危険物分類  6.1(b)
容器等級  III
HSコード  29322090
絵表示(GHS)
注意喚起語 Danger
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H301 飲み込むと有毒 急性毒性、経口 3 危険 P264, P270, P301+P310, P321, P330,P405, P501
H400 水生生物に強い毒性 水生環境有害性、急性毒性 1 警告 P273, P391, P501
注意書き

モキシデクチン 価格 もっと(18)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01COBQC-3757 モキシデクチン
Moxidectin
113507-06-5 250mg ¥16200 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01COBQC-3757 モキシデクチン
Moxidectin
113507-06-5 1g ¥34200 2018-12-26 購入
東京化成工業 M3136 モキシデクチン >98.0%(N)
Moxidectin >98.0%(N)
113507-06-5 250mg ¥12000 2018-12-04 購入
東京化成工業 M3136 モキシデクチン >98.0%(N)
Moxidectin >98.0%(N)
113507-06-5 1g ¥30500 2018-12-04 購入
関東化学株式会社(KANTO) 49832-75 モキシデクチン標準品
Moxidectin standard
113507-06-5 25mg ¥34000 2018-12-13 購入

モキシデクチン 化学特性,用途語,生産方法

効能

抗寄生虫薬 (獣医薬)

使用

anthelmintic, antiparasitic

使用

Moxidectin is a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is is fou nd in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep.

使用

Moxidectin is a semi-synthetic milbemycin derived from nemadectin by selective oxidation followed by methyloximation. Moxidectin was patented in 1991 as an anthelmintic for internal parasite control. The presence of the methyloxime affords moxidectin a greater hydrophobicity and longer biological half-life compared to nemadectin. Moxidectin binds selectively to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite.

Veterinary Drugs and Treatments

In dogs and cats, moxidectin with lufenuron is indicated as a once a month topical preventative for the prevention of heartworm, flea adulticide, ear mites (cats) and treatment for hookworms, roundworms, and whipworms (dogs). It has also been successfully used as a treatment for generalized demodicosis.
In cattle, moxidectin is indicated for the treatment and control of the following internal [adult and fourth stage larvae (L4)] and external parasites: Gastrointestinal roundworms: Ostertagia ostertagi (adult and L4, including inhibited larvae), Haemonchus placei (adult), Trichostrongylus axei (adult and L4), Trichostrongylus colubriformis (adult), Cooperia oncophora (adult), Cooperia punctata (adult), Bunostomum phlebotomum (adult), Oesophagostomum radiatum (adult), Nematodirus helvetianus (adult); Lungworm: Dictyocaulus viviparus (adult and L4); Cattle Grubs: Hypoderma bovis, Hypoderma lineatum Mites: Chorioptes bovis, Psoroptes ovis (Psoroptes communis var. bovis); Lice: Linognathus vituli, Haematopinus eurysternus, Solenopotes capillatus, Damalinia bovis; Horn flies: Haematobia irritans. To control infections and to protect from reinfection from Ostertagia ostertagi for 28 days after treatment and from Dictyocaulus viviparus for 42 days after treatment.
In sheep, oral moxidectin is indicated for the control of Haemonchus contortus (adult and L4), Teladosrsagia circumcincta & trifurcata (adult and L4), Trichostrongylus colubriformis, axei, & vitrinius (adult & L4), Cooperia curticei & oncophora (adult and L4), Oesophagostomum columbianum & venolosum (adult & L4), and Nematodirus battus, filicollis, & spathiger (adult & L4).
In horses and ponies, moxidectin is indicated for the treatment and control of the following stages of gastrointestinal parasites: Large strongyles: Strongylus vulgaris (adults and L4L5 arterial stages); Strongylus edentatus (adults and tissue stages); Triodontophorus brevicauda (adults); Triodontophorus serratus (adults); Small strongyles (adults and larvae): Cyathostomum spp. (adults); Cylicocyclus spp. (adults); Cylicostephanus spp. (adults); Gyalocephalus capitatus (adults); undifferentiated lumenal larvae; Encysted cyathostomes: late L3 and L4 mucosal cyathostome larvae; Ascarids: Parascaris equorum (adults and L4 larval stages); Pin worms: Oxyuris equi (adults and L4 larval stages); Hair worms: Trichostrongylus axei (adults); Large-mouth stomach worms: Habronema muscae (adults); Horse stomach bots: Gasterophilus intestinalis (2nd and 3rd instars). When combined with praziquantel, additional coverage against Anoplocephala spp. occurs.

モキシデクチン 上流と下流の製品情報

原材料

準備製品


モキシデクチン 生産企業

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113507-06-5(モキシデクチン)キーワード:


  • 113507-06-5
  • Moxidectin HOUSE STANDARD
  • Moxidectin,MilbeMycin B,23-MethoxiMe-LL-F 28249α,Equest,ProHeart 6
  • Cydectin, CL 301,423
  • Moxdectin
  • Milbemycin B, (6R,23E,25S)-5-O-DeMethyl-28-deoxy-25-[(1E)-1,3-diMethyl-1-buten-1-yl]-6,28-epoxy-23-(MethoxyiMino)
  • Moxidectin, >=98%
  • (6R,23E,25S)-5-O-DeMethyl-28-deoxy-25-[(1E)-1,3-diMethyl-1-buten-1-yl]-6,28-epoxy-23-(MethoxyiMino)MilbeMycin B
  • [6R,23E,25S(E)]-5-O-DeMethyl-28-deoxy-25-(1,3-diMethyl-1-butenyl)-6,28-epoxy-23-(MethoxyiMino)MilbeMycin B
  • 23-MethoxiMe-LL-F 28249α
  • Moxidectin
  • Milbemycin B, 5-O-demethyl-28-deoxy-25-(1E)-1,3-dimethyl-1-butenyl-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
  • proheart
  • Milbemycin B,5-O-demethyl-28-deoxy-25-(1,3-dimethyl-1-buten-1-yl)-6,28-epoxy-23-(methoxyimino)-,(6R,23E,25S)-
  • Moxidectin Solution, 100ppm
  • Equest
  • ProHeart 6
  • Quest
  • Vetdectin Oral Drench
  • モキシデクチン
  • モキシデクチン標準品
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