N-ALPHA-CBZ-ARG-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE
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N-ALPHA-CBZ-ARG-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE 속성
- 저장 조건
- -20°C
- 물리적 상태
- 수용액
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
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| 신호 어: | Danger | |||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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N-ALPHA-CBZ-ARG-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE C화학적 특성, 용도, 생산
용도
Z-Arg-Arg-7-amido-4-methylcoumarin hydrochloride has been used:- as a cathepsin B substrate in zymography analysis of protease in feces extract.
- in cathepsin B activity assay.
- as a fluorogenic peptide substrate to determine the matrix metalloproteinase enzyme activity.
일반 설명
Human cathepsin B (GenBank Accession No. NM_001908), CD33 signal peptide(amino acids 1-16) + Cathepsin B (amino acids 18-339), with C-terminal HIS tag, MW = 43 kDa, expressed in FreeStyle 293-F cells. Cathepsin B is a cysteine protease, found in the lysosome of normal cells and tissues. Cathepsin B active human is encoded by the gene CTSB, located on human chromosome 8p23.1.Biochem/physiol Actions
Cathepsin B Active human primarily is a preproenzyme, glycosylated on rough endoplasmic reticulum. Processing of procathepsin B to a 31 kDa, single chain active form occurs in the lysosome. It is further processed to double chain form with a 25/26 kDa heavy chain and 5 kDa heavy chain in lysosome. Cathepsin B, functions as an exopeptidase at low pH. At higher pH in endosomes or neutral pH, cathepsin B functions as endopeptidase. Cathepsin B expression is upregulated in malignant tumors and facilitates tumor invasion. Cathepsin B might reduce the production of amyloid-β peptide associated with Alzheimerβs disease. It also plays a key role in neuroprotective functions.N-ALPHA-CBZ-ARG-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE 준비 용품 및 원자재
원자재
준비 용품
N-ALPHA-CBZ-ARG-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE 공급 업체
글로벌( 62)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 |
1026@dideu.com | China | 9271 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10523 | 58 |
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 |
sales@anbuchem.com | China | 3000 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33349 | 58 |
| DONBOO AMINO ACID COMPANY | +8613063595538 |
donboo@donboo.com | China | 9365 | 58 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 |
sj_scrc@sinopharm.com | China | 9823 | 79 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 |
shenlinxing@macklin.cn | China | 15878 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 |
eric@peptidego.com | China | 6347 | 58 |
N-ALPHA-CBZ-ARG-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE 관련 검색:
L-(+)-아르기닌
Z-Arg-AMC
CATHEPSIN B SUBSTRATE I, COLORIMETRIC
N-ALPHA-CBZ-ARG-ARG-PRO-PHE-HIS-STA-ILE-HIS-N-EPSILON-BOC-LYS METHYL ESTER
NA-CBZ-ARG-ARG 4-METHOXY-B-NAPHTHYLAMIDE
Z-ARG-AMC HCL
Perindopril L-Arginine
N-ALPHA-CBZ-ARG-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE
Z-ARG-ARG-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN
BENZYL N-(2-AMINOETHYL)CARBAMATE HYDROCHLORIDE
N-ALPHA-CBZ-ARG-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE
H-ORN-AMC 2 HCL
L-ARGININE 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE
H-GLY-GLY-AMC HCL
H-ARG-ALA-NH2 2 HCL
L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE
2-(METHYLAMINO)-N-(4-METHYLPHENYL)ACETAMIDE HYDROCHLORIDE
H-ALA-ARG-AMC HCL