Z-ARG-ARG-MCA・HCL
Z-ARG-ARG-MCA・HCL 価格
もっと(5)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01H013123-V |
Z-Arg-Arg-MCA・HCl
Z-Arg-Arg-MCA.HCl |
136132-67-7 |
5mg |
￥10000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
C5429 |
Z-Arg-Arg-7-アミド-4-メチルクマリン 塩酸塩
Z-Arg-Arg-7-amido-4-methylcoumarin hydrochloride |
136132-67-7 |
5mg |
￥17400 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
SRP0289 |
recombinant, expressed in FreeStyle? 293-F cells, ≥90% (SDS-PAGE)
Cathepsin B Active human recombinant, expressed in FreeStyle? 293-F cells, ≥90% (SDS-PAGE) |
136132-67-7 |
10μG |
￥115000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
C5429 |
Z-Arg-Arg-7-アミド-4-メチルクマリン 塩酸塩
Z-Arg-Arg-7-amido-4-methylcoumarin hydrochloride |
136132-67-7 |
25mg |
￥57700 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
SRP0289 |
recombinant, expressed in FreeStyle? 293-F cells, ≥90% (SDS-PAGE)
Cathepsin B Active human recombinant, expressed in FreeStyle? 293-F cells, ≥90% (SDS-PAGE) |
136132-67-7 |
10ug |
￥87000 |
2018-12-25 |
購入 |
Z-ARG-ARG-MCA・HCL 化学特性,用途語,生産方法
使用
Z-Arg-Arg-7-amido-4-methylcoumarin hydrochloride has been used:
- as a cathepsin B substrate in zymography analysis of protease in feces extract.
- in cathepsin B activity assay.
- as a fluorogenic peptide substrate to determine the matrix metalloproteinase enzyme activity.
一般的な説明
Human cathepsin B (GenBank Accession No. NM_001908), CD33 signal peptide(amino acids 1-16) + Cathepsin B (amino acids 18-339), with C-terminal HIS tag, MW = 43 kDa, expressed in FreeStyle 293-F cells. Cathepsin B is a cysteine protease, found in the lysosome of normal cells and tissues. Cathepsin B active human is encoded by the gene CTSB, located on human chromosome 8p23.1.
Biochem/physiol Actions
Cathepsin B Active human primarily is a preproenzyme, glycosylated on rough endoplasmic reticulum. Processing of procathepsin B to a 31 kDa, single chain active form occurs in the lysosome. It is further processed to double chain form with a 25/26 kDa heavy chain and 5 kDa heavy chain in lysosome. Cathepsin B, functions as an exopeptidase at low pH. At higher pH in endosomes or neutral pH, cathepsin B functions as endopeptidase. Cathepsin B expression is upregulated in malignant tumors and facilitates tumor invasion. Cathepsin B might reduce the production of amyloid-β peptide associated with Alzheimerβs disease. It also plays a key role in neuroprotective functions.
Z-ARG-ARG-MCA・HCL 上流と下流の製品情報
原材料
準備製品
Z-ARG-ARG-MCA・HCL 生産企業
Global( 62)Suppliers
136132-67-7(Z-ARG-ARG-MCA・HCL)キーワード:
- 136132-67-7
- N-ALPHA-CBZ-ARG-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE
- Z-ARG-ARG-7-AMIDO-4-METHYL COUMARIN, DIHCL
- Z-ARG-ARG-AMC 2HCL
- Z-ARG-ARG-AMC HYDROCHLORIDE SALT
- Z-ARG-ARG-MCA HYDROCHLORIDE
- Z-ARG-ARG-MCA(HYDROCHLORIDE FORM)
- Z-L-ARGINYL-L-ARGININE-7-AMIDO-4-METHYLCOUMARIN 2HCL
- Z-RR-AMC, 2HCL
- z-arg-arg-7-amido-4-methylcoumarin hydrochloride
- z-rr-amc
- Z-ARG-ARG-MCA.HCL
- ANTI-CATB (CENTER) antibody produced in rabbit
- APP secretase
- CPSB
- CTSB
- Cathepsin B Active human
- BENZYLOXYCARBONYL-L-ARGINYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE
- CATHEPSIN B SUBSTRATE III, FLUOROGENIC
- CATHEPSIN B SUBSTRATE IV, FLUOROGENIC
- na-cbz-arg-arg 7-amido-4-methylcoumarin hydrochlo
- NA-CBZ-ARG-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORI
- N-CBZ-ILE-GLU-THR-ASP-7-AMINO-4- TRIFLUO ROMETHYLCOU
- Z-Arg-Arg-7-amido-4-methylcoumarin hydrochloride,Z-RR-AMC
- Z-Arg-Arg-AMC/Z-RR-AMC
- N-ALPHA-CBZ-ARG-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE USP/EP/BP
- Recombinant Mouse Cathepsin B/Ctsb Protein, His Tag
- Recombinant Human Cathepsin B/CTSB Protein, His Tag
- Z-Arg-Arg-7-amido-4-methylcoumarin
- CBZ-Arg-Arg-7-amido-4-methylcoumarin hydrochloride
- Mouse Anti-Caspase 8 antibody
- Z-ARG-ARG-MCA・HCL