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Hydroxypioglitazone

Hydroxypioglitazone 구조식 이미지

카스 번호:: 146062-44-4

상품명:: Hydroxypioglitazone

동의어(영문):: Leriglitazone;HYDROXYPIOGLITAZONE;Hydroxypioglitazone M4;Pioglitazone Impurity 4;Pioglitazone Impurity 18;Pioglitazone M4 Metabolite;Pioglitazone, hydroxy M-IV;Hydroxy Pioglitazone (M-IV);Hydroxy Pioglitazone Solution, 100ppm;5-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY] PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE

CBNumber:: CB1299313

분자식:: C19H20N2O4S

포뮬러 무게:: 372.44

MOL 파일:: 146062-44-4.mol

속성

안전

용도

공급 업체 72

Hydroxypioglitazone 속성

녹는점: 157-1580C

끓는 점: 627.6±55.0 °C(Predicted)

밀도: 1.325±0.06 g/cm3(Predicted)

저장 조건: -20°C Freezer, Under Inert Atmosphere

용해도: DMSO(약간 용해됨), 메탄올(약간 용해됨, 초음파처리)

산도 계수 (pKa): 6.35±0.50(Predicted)

물리적 상태: 고체

물리적 상태: 단단한 모양

색상: 흰색에서 황백색까지

안정성: 흡습성

CAS 데이터베이스: 146062-44-4

안전

Hydroxypioglitazone C화학적 특성, 용도, 생산

개요

Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor γ (PPARγ) agonist pioglitazone (Item Nos. 71745 | 22263 | 10028). It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4. Hydroxy pioglitazone binds to PPARγ (K_i = 1.2 μM) and activates PPARγ in a time-resolved FRET (TR-FRET) assay (EC₅₀ = 2.1 μM).

화학적 성질

Off-White Solid

용도

A metabolite of Pioglitazone (P471000).

Hydroxypioglitazone 준비 용품 및 원자재

원자재

Benzaldehyde, 4-[2-[5-[1-(methoxymethoxy)ethyl]-2-pyridinyl]ethoxy]- ethyl 3-(2-methyl-5-pyridyl)-3-oxopropionate 5-(1-(MethoxyMethoxy)ethyl)-2-Methylpyridine 2-(5-(1-(MethoxyMethoxy)ethyl)pyridin-2-yl)ethanol 5-(4-(2-(5-(1-(MethoxyMethoxy)ethyl)pyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 5-ACETYL-2-METHYLPYRIDINE Methyl 6-methylnicotinate

준비 용품

Hydroxypioglitazone 공급 업체

글로벌( 72)공급 업체

공급자	전화	이메일	국가	제품 수	이점
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9651	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69

Hydroxypioglitazone 관련 검색:

4'-히드록시아세토페논 Pioglitazone Pioglitazone Troglitazone Gliquidone Pioglitazone hydrochloride a-[(Aminocarbonyl)thio]-4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzenepropanoic Acid Ethyl Ester Pioglitazone Aldehyde Impurity 5-(4-Fluorobenzyl)-2,4-thiazolidinedione Pioglitazone Impurity 4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyaldehyde Hydroxy Pioglitazone (M-II) (Mixture of Diastereomers) Pioglitazone Sulfonic Acid IMpurity 2-[2-(4-BroMophenoxy)ethyl]-5-ethylpyridine 5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-2-imino-4-thiazolidinone Pioglitazone N-Oxide 5-(4-Hydroxybenzyl)-2,4-thiazolidinedione 5-[[4-[2-(5-ACETYL-2-PYRIDINYL)ETHOXY]PHENYL]METHYL]-2,4THIAZOLIDINEDIONE