23-HYDROXYBETULINIC ACID

23-HYDROXYBETULINIC ACID 구조식 이미지
카스 번호:
85999-40-2
상품명:
23-HYDROXYBETULINIC ACID
동의어(영문):
ANEMOSAPOGININ;23-HYDROXYBETULINIC ACID;23-Hydroxybetulinic Acid, ≥98%;23-hydroxy butulinic acid (23-HBA);23-HYDROXYBETULINIC ACID USP/EP/BP;23-Hydroxybetulinic acid 85999-40-2;Anemosapogenin,23-Hydroxybetulinic acid;3β,23-Dihydroxylup-20(29)-en-28-oic acid;23-Hydroxybetulinic acid (Anemosapogenin);3beta,23-Dihydroxylup-20(29)-en-28-oic acid
CBNumber:
CB1694435
분자식:
C30H48O4
포뮬러 무게:
472.7
MOL 파일:
85999-40-2.mol
MSDS 파일:
SDS

23-HYDROXYBETULINIC ACID 속성

녹는점
>293°C (dec.)
끓는 점
585.8±25.0 °C(Predicted)
밀도
1.106
저장 조건
-20°C Freezer, Under inert atmosphere
용해도
메탄올(약간, 가열), 피리딘(약간)에 용해됨
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
4.60±0.70(Predicted)
색상
하얀색

안전

23-HYDROXYBETULINIC ACID C화학적 특성, 용도, 생산

개요

23-hydroxy Betulinic acid is a triterpenoid that has been found in P. chinensis and has anticancer activity. It inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 μM, respectively), as well as human umbilical vein endothelial cells (HUVECs; IC50 = 94.8 μM). It halts the cell cycle at the S phase and induces apoptosis in K562 cells in a concentration-dependent manner with a loss of the mitochondrial membrane potential and an increase in Bax and cytochrome C protein levels.

용도

23-Hydroxybetulinic Acid is a potential cytoxic agent in the treatment of cancer. Apoptotic effect. Antiproliferative.

23-HYDROXYBETULINIC ACID 준비 용품 및 원자재

원자재

준비 용품


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